This is an automatically translated article.
Cadipredni with the main active ingredient is Prednisolone, is a corticosteroid with anti-inflammatory, anti-allergic effects and if used in high doses, has an immunosuppressive effect. Medicines are indicated in many cases to reduce inflammation and reduce allergies. Although the drug has many good uses, if used incorrectly also causes many disadvantages.
1. What are the effects of Cadipredni?
Cadipredni drug has the composition of Prednisolone 5mg, prepared in the form of film-coated tablets.
In which:
Prednisolone is a Glucocorticoid with pronounced anti-inflammatory, anti-allergic and immunosuppressive effects. Prednisolone has only a weak mineralocorticoid effect, so if taken for a long time there is very little risk between sodium and edema. The anti-inflammatory effects of prednisolone are equivalent to 4mg of methylprednisolone and 20mg of hydrocortisone. The mechanism of action of the drug is because Prednisolone inhibits leukocytes from extravasating and infiltrating the inflamed tissue, reducing the number of lymphocytes, eosinophils, and monocytes in the peripheral blood and reducing their migration. of them into the inflamed area. Prednisolone also reduces prostaglandin synthesis by inhibiting phospholipase A2. As a result, the drug helps to reduce the occurrence of inflammatory reactions. At low doses, Glucocorticoids have anti-inflammatory and allergy-reducing effects. In high doses, glucocorticoids have an immunosuppressive effect.
2. Indications and contraindications of the drug Cadipredni
Indications:
Cadipredni drug is widely indicated in the following diseases:
Iritis, iritis - blepharitis, episcleritis, uveitis. Vasculitis: Inflammation of the temporal artery and around the nodal artery, sarcoidosis; Asthma: Prednisolone is also used in asthma because it has been shown to be effective in severe asthma, demonstrating the role of inflammation in the immune pathogenesis of this disease. Ulcerative colitis, hemolytic anemia, agranulocytosis and allergic diseases including anaphylaxis. Cancer such as acute leukemia; lymphoma, breast cancer, prostate cancer in the late stages. Acute and chronic polyarthritis; periarthritis, ankylosing spondylitis, rheumatism, rheumatic heart disease, systemic lupus erythematosus. Addison's disease, acute adrenal insufficiency, adrenal-genital syndrome. Pemphigus, erythema nodosum; eczema, allergic pruritus, exfoliative dermatitis and psoriasis. Contraindications:
Do not use Cadipredni in the following cases:
Untreated acute purulent eye infection, acute superficial herpes simplex infection; Chickenpox, other viral diseases of the cornea and conjunctiva, ocular tuberculosis, and eye fungus. Severe infections unless septic shock and tuberculous meningitis. There has been a history of hypersensitivity to Prednisolone or any other active ingredient. Taking a live vaccine. Duodenal ulcer, osteoporosis and severe neuropsychiatric disease.
3. Dosage and how to use Cadipredni
How to use:
Cadipredni is made in the form of film-coated tablets, should be taken orally. Time to take the drug is 8 to 9 am, after eating if used 1 time. When taking 2 times, you divide one dose in the morning and one dose about 17h-18 hours after eating. In case of high dose or prolonged use for more than 10 days, do not stop taking the drug suddenly. It is necessary to gradually reduce the dose according to the instructions when stopping the drug. If taken long-term, it may be necessary to take it every other day, which can help reduce the risk of side effects. Dosage:
Adults: The starting dose for adults can be from 5 to 60mg/day. Depending on the severity of the disease, treatment is usually divided into 1 to 2 times per day. The dose for children can be from 0.14 to 2mg/kg/day, given once or divided into several times daily.
4. Side effects of drugs Cadipredni
In addition to the main effects of the drug, when taking Cadipredni you may experience the following side effects:
Lower blood pressure, alkalinize the blood, water and salt retention sometimes cause high blood pressure or lead to congestive heart failure. Endocrine and metabolic disorders: Cushing's syndrome often with prolonged use, ACTH secretion cessation, (sometimes permanent), reversible impaired glucose tolerance, latent diabetes, growth arrest when used in children, sometimes when causing irregular menstruation and hirsutism. Musculoskeletal disorders: Muscle atrophy, muscle weakness, osteoporosis (sometimes permanent osteoporosis), pathological fractures, especially vertebral depression, non-infectious osteonecrosis of the femoral neck and ligament rupture. Gastrointestinal disorders: Peptic ulcer, bleeding, gastrointestinal perforation, acute pancreatitis. On the skin: Skin atrophy, slow healing of scars, purpura, ecchymosis, acne. Nervous disorders: Excessive excitement, euphoria, sleep disturbance. Rarely, extreme mania, confusion, delirium, or convulsions have been reported when the drug is discontinued. Eye disorders: Glaucoma, cataract-increased intracranial pressure (due to abrupt discontinuation of the drug). When taking the drug, if there are any abnormal signs, you need to immediately notify your doctor for timely treatment.
5. Things to keep in mind when using Cadipredni
This is a prescription drug, only used according to the doctor's prescription, do not arbitrarily use or stop taking the drug without consulting the doctor. Taking the correct medication helps to reduce the risk of side effects. The side effects of this medicine may be worse in patients with hypothyroidism or cirrhosis of the liver. Therefore, close monitoring or dose modification is required in these patients. It should be used with caution in patients with osteopenia, those with recent vascular access, those with a history of psychiatric disorders, and a history of gastric and duodenal ulcers. Because taking this medicine can increase the severity of the above diseases. When taking this medicine, you may increase your risk of infection, so pay attention to ensure food hygiene, body hygiene and avoid the source of infection. Pregnancy and breast-feeding: For pregnant women, using this drug may affect the fetus such as reducing the weight of the fetus, so the use of the drug should be carefully considered. Breastfeeding women, although there are no contraindications, should be carefully considered before using the drug. Avoid getting vaccinated while on medication, especially live attenuated vaccines, as this can put you at risk for post-vaccination disease and reduce the effectiveness of the vaccine. Drug interactions may occur when used concomitantly with non-steroidal anti-inflammatory drugs, anti-inflammatory drugs with similar composition, sympathomimetic agents, antacids, etc. These drugs may increase the risk of side effects or decrease the main effect. This drug can increase blood sugar when used, so it should be used with caution in people with diabetes and if necessary, the dose of antidiabetic drugs may need to be adjusted. Above is some information about the drug Cadipredni, to better understand the drug you need to consult a pharmacist or doctor. If you need to take medication, you need to take it exactly as directed to avoid the risk of side effects.
