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The drug Cadilanso with the main ingredient is Lansoprazole, an active ingredient that has an anti-secretory effect on gastric acid. The drug is indicated for use in the case of diseases that increase acid secretion, peptic ulcer ... To better understand the use of the drug, please read through the article below.
1. What is Cadilanso?
Cadilanso drug has the main ingredient is Lansoprazole 30mg, prepared under hard capsules. Lansoprazole is an active ingredient in the group of anti-secretory agents, a benzimidazole derivative, which has no anticholinergic or antihistamine effects at the H2 receptor, but this active ingredient prevents gastric acid secretion by inhibiting the gastrointestinal tract. (H+, K+)-ATPase (proton pump) at the secretory surface of gastritis cells.
Because this enzyme system is considered to be the acid pump inside the parietal cell, lansoprazole inhibits the gastric acid pump by blocking the final step in acid production. This effect is dose-related and usually results in inhibition of gastric acid secretion at normal and when stimulated by any stimulant. The drug does not change the total amount of gastric juice, but reduces the acid in the gastric juice.
2. Indications and contraindications of the drug Cadilanso
Indications:
The drug Cadilanso is indicated for use in the following cases:
Treatment of advanced gastric and duodenal ulcers; Treatment of esophagitis caused by gastroesophageal reflux disease; Treatment of Zollinger-Ellison syndrome. Contraindications:
Cadilanso is contraindicated in the following cases:
Patients with hypersensitivity to Lansoprazole or to any of its ingredients; Pregnant and lactating women should not use; Children.
3. Dosage and usage of the drug Cadilanso
How to use:
The drug is taken orally. When taking, should be swallowed whole 30 to 60 minutes before eating, do not break or chew the capsule.
Dosage:
Stomach ulcer progress: Take 1 tablet and 1 time a day, for 4 consecutive weeks, if necessary, can continue for another 2-4 weeks. Esophagitis due to gastroesophageal reflux - oesophagitis: Take one tablet and take it once a day for 4 weeks, if necessary can continue for another 4 weeks. Zollinger-Ellison syndrome: Often requires higher doses. Take 1-2 tablets x 1 time/day. The duration of treatment depends on the pathological response. Treatment should not be stopped abruptly. In patients with hepatic impairment: Dosage reduction is required in patients with severe liver disease. Elderly: Lansoprazole should be used with caution because gastric acid secretion and other physiological functions have been impaired. Missed dose: If you miss a dose, take it before the next meal. If you remember it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Note: Do not take double the prescribed dose.
4. Side effects of the drug Cadilanso
When using Cadilanso, you may encounter unwanted effects:
Common: Headache, dizziness; Diarrhea, abdominal pain, nausea, vomiting, constipation, indigestion; Rash. Uncommon: Fatigue; Increased serum gastrin level; increased liver enzymes, hematocrit, hemoglobin, uric acid and proteinuria appeared. When experiencing side effects of the drug, you need to notify your doctor or go to the nearest medical facility for timely treatment.
5. Note when using Cadilanso
Before using the drug, tell your doctor about any allergies, medical conditions and if you are pregnant, suspect pregnant or breast-feeding. Use of proton pump inhibitors, including Cadilanso, especially when used in high doses and for long periods of time (> 1 year), may slightly increase the risk of hip, wrist, and spine fractures. Weakness occurs in the elderly or those with other risk factors. Observational studies have shown that proton pump inhibitors increase the risk of fracture by 10 to 40%, in some cases possibly due to other factors. Patients at risk of osteoporosis must be cared for according to existing guidelines and should be adequately supplemented with vitamin D and calcium. Severe hypomagnesaemia has been reported in patients treated with proton pump inhibitors for at least 3 months and in most cases for about 1 year. Symptoms of severe hypomagnesaemia may include fatigue, muscle spasms, delirium, convulsions, dizziness, and ventricular arrhythmias, but these symptoms can be insidious and often go unnoticed. arrive. In the majority of patients with hypomagnesaemia, the condition improves after magnesium supplementation and discontinuation of proton pump inhibitors. Therefore, when using the drug, it is necessary to measure magnesium levels before starting treatment and periodically during treatment for patients who need long-term treatment or must take proton pump inhibitors concurrently with some drugs such as digoxin or drugs that cause hypomagnesaemia (diuretics). The use of antacids may increase the risk of gastrointestinal infections. Ensure a food-safe diet to help reduce the risk of gastrointestinal infections. For children: Because efficacy and tolerability have not been studied. Therefore, it is best not to give the drug to children. Ability to drive and use machines: Undesirable effects caused by Cadilanso such as dizziness, lightheadedness, decreased vision and somnolence may occur and affect the ability to drive. Care should be taken when driving or operating machinery. Pregnancy and breast-feeding: Due to the lack of adequate research on the use of the drug during pregnancy and lactation, the drug should only be used when clearly needed.
6. Cadilanso drug interactions
Lansoprazole may alter the metabolism of drugs metabolised by the cytochrome P450 system such as warfarin, antipyrin, indomethacin, ibuprofen, phenytoin, propranolol, prednisone, diazepam, clarithromycin. When lansoprazole was co-administered with theophylline, theophylline clearance was slightly increased (10%). Affects the effect of the drug. Lansoprazole may cause a prolongation of the elimination half-life of diazepam, warfarin, and phenytoin. Lansoprazole reduces the absorption of drugs whose absorption is pH dependent, such as ketoconazole and itraconazole. With voriconazole, plasma concentrations of both drugs are increased and a reduction in the dose of lansoprazole is recommended. Antacids and Sucralfate: Concomitant administration and within 1 hour of lansoprazole should be avoided because these drugs reduce the bioavailability of lansoprazole. Store Cadilanso in a tightly closed container, in a dry place, away from light. Storage temperature should not exceed 30°C. Keep medicine out of reach of children. Do not use the drug whenHopefully, with the information about the drug Cadilanso you already know what the drug is for, how to use it and what to pay attention to when using. Take this medicine exactly as directed and if you do not understand it, consult your doctor or pharmacist to make sure it is safe.
