Uses of Bloza

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1. What disease does Bloza treat?

What is Bloza? The drug contains the active ingredient Losartan 50mg. Losartan belongs to the group of angiotensin II receptor antagonists, has the effect of reducing blood pressure, slowing down the decline of kidney function in hypertensive patients with type 2 diabetes.
Regarding the mechanism of action, Losartan does Angiotensin II's vasoconstriction and aldosterone secretion is due to its ability to inhibit ACE and is a catalyst for Bradykinin degradation. As a result, this ingredient has an anti-hypertensive effect.
Indications for using Bloza:
Treatment of hypertension; Renal protection in patients with hypertension and type 2 diabetes with laboratory signs of renal failure and proteinuria greater than 0.5g/day (abnormal protein in the urine); Treatment of chronic heart failure when the use of other angiotensin-converting enzyme inhibitors (ACE inhibitors, antihypertensives) is not appropriate. If heart failure remains stable with an ACE inhibitor, there is no need to switch to losartan; Reduced risk of stroke in hypertensive patients with left ventricular hypertrophy. Contraindications to the use of Bloza:
People with a history of allergy to Losartan or other excipients of the drug; Patients with severe liver failure; Pregnant and lactating women; Children under 18.

2. How to use and dose Bloza

Usage: Orally. The patient should swallow the tablet whole with 1 glass of water, with or without food. Besides, you should try to take the medicine at the same time every day. People with high blood pressure should combine the use of drugs with a scientific diet and healthy lifestyle. At the same time, it is necessary to have knowledge to handle in case of sudden increase in blood pressure.
Dosage: As prescribed by the doctor in accordance with the general health condition of the patient. Specifically:
Hypertension in adults (with or without type 2 diabetes): The starting dose is 50mg/time/day. Depending on the response of the patient, the dose may be increased to 100 mg/day in some patients. The maximum antihypertensive effect of the drug is usually achieved after 3-6 weeks of dosing. In addition, Bloza can be combined well with insulin and other common hypoglycemic agents such as glitazone, sulfonylurea and glucosidase inhibitors; Heart failure in adults: The starting dose is 12.5 mg/day. The dose can then be increased gradually week by week until a maintenance dose of 50 mg/day is reached. For example, the first week of taking a dose of 12.5mg/day; Week 2 is 25mg/day and week 3 is 50mg/day. Usually, Bloza is combined with a diuretic, digitalis (to help keep the heart healthy and work more efficiently) or a beta-blocker; Patients with a history of liver failure, people over 75 years old, people with intravascular volume depletion: The starting dose should be 25mg/time/day; Children: The safety and effectiveness of losartan have not been established in children under 6 years of age. Overdose: When using an overdose of Bloza, the patient is at risk of a rapid drop in blood pressure and an irregular heartbeat (fast or slow). To ensure safety, patients should immediately call 911 or go to the nearest hospital for timely treatment.
Missed dose: If you forget to take a dose of Bloza, you should take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.

3. Side effects of the drug Bloza

When using Bloza, patients may experience some side effects such as:
Common: Dizziness, fatigue, weakness, hypotension, hypoglycemia, hyperkalemia; Uncommon: Somnolence, headache, sleep disturbance, tachycardia, angina pectoris, skin itching, edema, rash, dyspnoea, laryngitis, abdominal pain, persistent constipation, diarrhea, sadness vomiting, vomiting; Rare: Vasculitis (including Henoch-Schonlein purpura), numbness or tingling (paresthesia), hepatitis, irregular heartbeat, fainting, stroke, elevated ALT levels bleeding (usually goes away on its own after stopping the drug); Frequency not known: Thrombocytopenia, red blood cell count, migraine, flu-like symptoms, abnormal liver function, muscle and joint pain, back pain, urinary tract infection, increased sensitivity to light morning, pancreatitis, impotence, impotence, hyponatremia, depression, tinnitus, depression, uremia, serum potassium and serum creatinine in patients with heart failure. Patients should notify their doctor if they experience any abnormality after using Bloza for advice on appropriate management.

4. Precautions when using Bloza

Some notes for patients to remember before and during Bloza use:
Closely monitor and consider dose reduction when using Bloza in patients with risk factors for hypotension, for example: are being treated with diuretics, have a salt-restricted diet, are dehydrated, have persistent diarrhea or vomiting; Adverse events such as increased blood urea and serum creatinine have occurred in patients with isolated renal artery stenosis, bilateral renal artery stenosis, or single kidney remaining. Should be cautious when using Bloza in this group of subjects; It is necessary to regularly check the amount of potassium in the blood in patients with poor kidney function and the elderly (over 75 years old) to prevent the risk of electrolyte imbalance; Patients with mild and moderate hepatic impairment need to reduce the dose of Bloza because the concentration of the drug and its metabolites in the blood may be increased if liver function is impaired; Do not use Bloza in pregnant women to avoid the risk of fetal diseases, even death; It is not known whether Losartan is excreted in human milk, so nursing mothers should consider discontinuing nursing or discontinuing the drug (depending on the importance of the drug to the mother); The side effects of Bloza may affect the ability to drive and use machines. Therefore, caution should be exercised when using the drug in this case.

5. Bloza drug interactions

Drugs that may interact with Bloza include: Thiazide diuretics, potassium-sparing diuretics (amiloride, triamterene, spironolactone), Aliskiren, ACE inhibitors, antipsychotics, tricyclic antidepressants, Amifostine, Baclofene, Heparin, Lithium, alcohol,...
When using Bloza, patients should maintain a suitable lifestyle and exercise regimen. At the same time, patients need to strictly follow the doctor's instructions on how to use, the dose of the drug to ensure the effectiveness of treatment, to avoid the risk of encountering dangerous incidents and side effects.

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