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Bisohexal 5 mg is a medicine used to treat hypertension and angina pectoris. To learn more about the use and dosage of the drug, you can refer to the article below.
1. Main ingredients of bisohexal
The drug bisohexal 5mg is in the form of tablets. Each tablet contains the following ingredients:
Bisoprolol fumarate 5mg; Excipients are sufficient.
2. Uses of Bisohexal
Bisohexal is a selective Beta 1 - adrenergic receptor blocker with no membrane stabilizing properties and no intrinsic sympathomimetic effects. When used at low doses, bisoprolol selectively inhibits the response to adrenergic stimulation by competitively blocking beta 1 - adrenergic receptors of the heart. When Bisoprolol is used in high doses, the selectivity of Bisoprolol on Beta 1 - adrenergic receptors is often reduced and the drug will competitively inhibit both Beta 1 and Beta 2 - adrenergic receptors.
About absorption, Bisohexal drug is completely absorbed from the gastrointestinal tract, less metabolized by the liver for the first time. Peak plasma concentrations are reached 2 to 4 hours after oral administration. The drug is eliminated in the urine and has a plasma half-life of about 10-12 hours.
Bisohexal is indicated for use in the following cases:
Control of hypertension; Control angina pectoris ; Combination therapy in patients with stable chronic heart failure.
3. Dosage and how to use Bisohexal
How to use: Bisoprolol is made in the form of tablets, it is best to take it orally.
About dosage:
In case of controlling hypertension or angina: Take 5 - 10 mg x 1 time / day, the maximum dose is 20 mg / day. In case of congestive heart failure: Take 1.25 mg x 1 time/day. Evaluating good tolerability, the dose may be doubled after 1 week and then gradually increased over 1 to 4 weeks to the maximum tolerated dose. Attention should not exceed 10 mg / time / day. In patients with hepatic and renal impairment: Take 2.5 mg/time/day and gradually increase the dose until response. Maximum dose 10mg/time/day.
4. What to do when overdose or forget dose of Bisohexal?
When an overdose of the drug Bisohexal you may appear the following symptoms:
Bradycardia; Blood pressure drops; Congestive heart failure; Lower blood sugar. When you encounter this problem, you need to calmly handle the following: Stop taking Bisoprolol and start symptomatic treatment. For example: If the heart rate is slow, Atropin should be given intravenously. If blood pressure is low, intravenous fluids and medications to raise blood pressure should be used, etc. However, these are the reference treatment directions, to ensure safety and have the right treatment, you need to go to the hospital right away. nearest health facility.
When you miss a dose of Bisohexal, do the following: Take Bisohexal as soon as possible, preferably as soon as you remember. However, if the missed dose is close to the next dose, skip the missed dose and take your next dose at the scheduled time. Do not take twice the prescribed dose to make up for the missed dose.
5. Undesirable effects when using Bisohexal
In the process of taking Bisohexal you may experience unwanted effects:
Dizziness, dizziness, drowsiness, headache, anxiety, restlessness, memory loss; Dry lips and thirst; Bradycardia, palpitations, palpitations; Hypotension ; Chest pain; Shortness of breath; Mental disorders and depression; Sleep disorders; Stomach ulcers ; Indigestion, constipation, vomiting and nausea; Osteoarthritis and back pain; Itching, allergies and rashes; Visual disturbances; Metabolic disorder. The above may not be all the unwanted effects of bisoprolol. Therefore, if you experience any symptoms of discomfort while taking the drug, immediately notify the medical staff.
6. Contraindications to Bisohexal
Bisohexal 5mg is not indicated for people with:
Acute heart failure, decompensated heart failure and cardiogenic shock; Second or third degree atrioventricular block; Sinus node insufficiency syndrome; Sinus atrial block; bradycardia less than 60 beats/min; Systolic blood pressure less than 100 mmHg and hypotension; Acute bronchial asthma or chronic obstructive pulmonary disease acute COPD; metabolic acidosis; Patients with hypersensitivity to Bisoprolol Stada or any of its ingredients.
7. Be careful when using Bisohexal
Be careful when using Bisohexal in the following cases:
Liver failure; Heart failure ; CKD; Peripheral vascular diseases; COPD disease; Diabetes mellitus; Low blood sugar; Thyroid disease; Pregnant and lactating women.
8. Bisohexal drug interactions with other drugs
Bisohexal may interact with:
Reserpine or Guanethidine drugs, Clonidine. Drugs that inhibit the myocardium or inhibit atrioventricular conduction, such as: Phenylalkylamine (Verapamil) and Benzothiazepine (Diltiazem), Disopyramide. Rifampicin . Above is detailed information about the uses as well as indications when using Bisohexal 5mg medicine. To ensure the safety of using the drug, you should consult your doctor before use.
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