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Bendamustine is used to treat problems with chronic lymphocytic leukemia. Side effects from medications can be mild or serious. Therefore, you need to make sure that you take the medicine exactly as directed by your doctor to be effective. Here is some information to share about Bendamustine
1. How is Bendamustine?
Bendamustin e is usually indicated for chronic lymphocytic leukemia. This drug is also used for B-cell non-Hodgkin's lymphoma. After the trial of its use with lymphoma, there were no positive signs. You should consult your doctor and rely on actual results to determine the effectiveness of the drug in treatment.
2. Dosage and instructions for use of Bendamustine
Bendamustine is used intravenously. After about 21 - 28 days you may be prescribed injections for 2 consecutive days. The duration of drug use for treatment depends on the severity of the disease under consideration. If after the injection you feel burning, painful swelling and discomfort, please notify your doctor for examination. Some patients can combine it with other drugs to prevent the side effects caused by Bendamustine.
Chronic lymphocytic leukemia Use 100mg/m2 for each treatment and the course lasts for 6 weeks. Each use will be infused over 30 minutes under the supervision of a physician. How to use the doctor will guide you specifically when doing it.
Non-Hodgkin Lymphoma Use 100mg/m2 for each treatment and the course lasts for 8 weeks. Each dose will take about 60 minutes to infuse. This method should be used when the patient's condition has improved or has undergone treatment within 6 months with rituximab.
3. Notes before taking Bendamustine
When using Bendamustine, if you develop a rash or an allergic reaction, tell your doctor. In case of severe effects, consider adjusting the dose or temporarily stopping use to reduce allergies. Before taking the drug, the patient should inform the doctor if he has ever been in one or more of the following cases:
Weakened immune system; Infection leading to high fever; People with tuberculosis ; Having shingles ; The body has problems with metabolism or electrolyte imbalance; Diseases of the liver and kidneys; Subjects have a habit of smoking. Bendamustine may lead to an increased risk of unwanted cancer syndromes. If you are suffering from cancer, you need to pay attention to this problem because after using it can make cancer cells grow faster and stronger. Women during pregnancy are contraindicated to use the drug Bendamustine.
Men and women planning to have children should consider if they have used Bendamustine. In men, it takes 3 months after stopping the drug and 6 months in women to limit the risk of birth defects. You should use birth control while taking the drug to avoid unwanted pregnancy affecting the fetus.
If the birth control method is not effective, you need to report it to your doctor as soon as possible so that it can be considered. Men may experience infertility or reduced fertility after taking Bendamustine. Therefore, it is necessary to pay attention to regular health monitoring to ensure the lowest level of impact.
When using Bendamustine the body's immune system may be affected. You should take care to avoid infections that are dangerous to your health. Always check your health regularly and pay attention. If you have symptoms or have ever had hepatitis B, you need your doctor to stop taking your medication.
4. Bendamustine side effects
If after taking the drug, your body shows signs of an allergic reaction, you need to immediately report it to your doctor for consideration. An allergy to Bendamustine may be a rash. swelling, difficulty breathing. But if there are signs of fever, pain, burning... you should not be subjective and must report to the doctor for examination and emergency preparation if the situation worsens.
Common side effects to watch out for:
High fever; Infection at the injection site; Allergy; Red swelling; Vomit; Diarrhea; Anorexia; Jaundice; Visual impairment; Anemia; Skin sores; Dizzy; Shortness of breath; Confusion; Asthenia; Cramp; Heart rhythm disturbances; Numbness and tingling in the limbs; Weight loss. These side effects are common in most patients. However, in addition, you should also monitor if there is anything abnormal in your body, quickly go to the hospital for examination and treatment.
5. Some interactions with the drug Bendamustine
Avoid using Bendamustine with other drugs when the risk of drug interactions is unknown. Especially some drugs that can affect blood levels of Bendamustine will reduce effectiveness and increase the risk of side effects such as allopurinol.
You need to inform your doctor about any medications you are taking for treatment or health improvement. Whether it is vitamins, over-the-counter or prescription drugs, there is a potential for interaction with Bendamustine.
Above is some information to share for you to understand what Bendamustine is used for. Always remember to use the medicine only with specific instructions from your doctor. After taking the drug, if the body shows abnormal signs, quickly go to the hospital for examination or emergency.
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References: drugs.com
