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Bambuterol 10 A.T has the main active ingredient is Bambuterol hydrochloride with a strength of 10mg. This is a popular drug known for its expectorant effect, except for the treatment of people with bronchitis.
1. Uses of Bambuterol 10
What is Bambuterol 10? Bambuterol 10 A.T contains the active ingredient Bambuterol hydrochloride. This is a drug that belongs to a group of drugs that are effective in the respiratory tract. Bambuterol is a precursor of Terbutaline, a beta-receptor agonist, selectively stimulating on Beta-2. The drug has the effect of relaxing bronchial smooth muscle, blocking the production of endogenous spasmolytic substances, neutralizing the edema reaction caused by endogenous chemical mediators and increasing the clearance of the system. mucilage system.
Bambuterol 10 A.T is indicated in the treatment of diseases:
Treatment of asthma; Treatment of bronchospasm and/or reversible airway obstruction.
2. Usage and dosage of Bambuterol 10
Bambuterol 10 A.T is used orally, you should take it before sleeping.
Treatment dose for adults
Initial treatment dose: use 10 mg - 20 mg. You may increase the therapeutic dose to 20 mg if necessary after 1–2 weeks, depending on clinical efficacy. In patients who are well tolerated by a prior β2 agonist, the recommended starting and maintenance dose is 20 mg. Treatment dose for children
In children from 2 to under 6 years old: dose 10 mg x 1 time / day; Due to differences in pharmacokinetics, an initial dose of 5 mg once daily is recommended for Asian children. Children from 6 to 12 years old: dose 10 to 20 mg x 1 time / day; Due to differences in pharmacokinetics, an initial dose of 5 mg once daily is recommended in Asian children and doses > 10 mg are not recommended. For the elderly” No dose adjustment is required.
For people with liver failure
People with significant liver dysfunction: Bambuterol 10 A.T should not be used because the rate at which the drug is converted to terbutaline cannot be predicted. In patients with cirrhosis or with severe (any cause) impaired hepatic function, the daily dose must be individualized, taking into account the individual's potential for impaired metabolism. convert bambuterol to terbutaline. Therefore, direct administration of the active metabolite (terbutaline) is preferred for these patients. For patients with renal impairment: Moderate to severe impairment of renal function (GFR <50 ml/min): It is recommended that the starting dose be halved.
In case of overdose, you may experience some of the following signs and symptoms when using Bambuterol 10 A.T. Specific overdose: headache, anxiety, tremor, nausea, muscle cramps, drumming chest, tachycardia and arrhythmia, hypotension. Significant inhibition of plasma cholinesterase may persist for several days. In the case of a particularly severe overdose, the treating physician will consider gastric lavage and activated charcoal on a case-by-case basis.
If you forget to take a dose, you should try to take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. You should never take more than double the prescribed dose.
3. Undesirable effects of the drug Bambuterol 10 A.T
In the case of an overdose of Bambuterol 10 A.T, you may experience unwanted effects, specifically as follows:
Behavioral disturbances such as restlessness, tremor or headache. Sleep disturbance, palpitations, muscle spasticity. Behavioral disturbances such as agitation, tachycardia, arrhythmias, specifically atrial fibrillation, supraventricular tachycardia and extrasystoles. Hypersensitivity reactions include angioedema, urticaria, erythema, bronchospasm, hypotension and collapse, hypokalemia, hyperglycemia, dizziness, hyperactivity, muscle ischemia heart, nausea.
4. Interactions of Bambuterol 10 A.T
Interaction of Bambuterol 10 A.T with other drugs
Co-administration of Bambuterol 10 A.T with halothane anesthetics: Increased risk of cardiac arrhythmias, avoid halothane anesthesia during β2 agonist therapy. Other halogenated anesthetics should be used with caution in conjunction with β2 agonists. Concomitant use with Suxamethonium: Prolong the muscle relaxant effect of Suxamethonium. Beta-receptor blockers include eye drops, especially non-selective blockers, which may cause partial or complete inhibition of the effects of beta-agonists. Bambuterol 10 A.T should not be used concurrently. Drugs that reduce potassium and hypokalemia such as diuretics, methyl xanthine and corticosteroids, other sympathomimetic agents: Risk of causing hypokalemia. Caution should be exercised when using the drug, especially noting that it may lead to an increased risk of arrhythmias caused by hypokalemia. Hypokalemia can also lead to Digoxin toxicity. Bambuterol 10 A.T. drug interactions may change how the medicine works or increase the effects of unwanted effects on your health. The information provided above does not cover all possible drug interactions. You need to provide your treating doctor with a list of all the medications you are taking, including prescription and nonprescription drugs, and dietary supplements, so that they can be adjusted accordingly.
5. Some notes when using Bambuterol 10 A.T
Use with caution in people with liver dysfunction, people with thyrotoxicosis and severe cardiovascular disease such as ischemic heart disease, tachycardia or severe heart failure. It is necessary to monitor the concentration of potassium in the blood during the use of the drug. Do not use the drug for a long time that may aggravate or recur in the symptoms of the disease, in case it is absolutely necessary to consult your doctor or other medical professional Before driving and When operating machinery, it is necessary to pay attention to assess the state of the body, to avoid unwanted effects of Bambuterol 10 A.T that may affect work. You should not arbitrarily stop using Bambuterol 10 A.T. Although, to date, there are no data on the effects of Bambuterol 10 A.T on pregnant women, caution should be exercised when using the drug in the first 3 months of pregnancy. You should consult your doctor before using the drug for pregnant and breastfeeding women.
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