This is an automatically translated article.
Bactronil medicine with mupirocin 2% is made in the form of an ointment for topical application. The drug is indicated in the treatment of primary or secondary bacterial infections caused by Staphylococcus aureus or other sensitive bacteria such as impetigo, folliculitis, boils... However, Bactronil can cause cause some unwanted side effects. Therefore, before using the drug, the patient should learn carefully and get advice from the treating doctor.
1. Mechanism of action of the drug Bactronil
Bactronil medicine contains mupirocin which belongs to the group of antibiotics extracted from pseudomonas fluorescen. The drug has a bactericidal effect against all types of streptococcus and staphylococcus that are greasy with methionine compounds. Bactronil inhibits bacterial protein synthesis by reversibly binding to isoleucyl RNAt Synthetase - which catalyzes the formation of isoleucyl-RNAt and RNAt. At the same time, the effect of Bactronil drug also helps to inhibit bacteria at low concentrations as well as kill bacteria at high concentrations. After using the drug can reach bactericidal concentration in the skin.
For the human body, Bactronil drug with mupirocin component penetrates the skin intact but the rate of systemic absorption is quite low. When entering the body, Bactronil is rapidly metabolised to an inactive metabolite, monic acid, which is also rapidly excreted by the kidneys. Thus, Bactronil with mupirocin compound has local antibacterial properties and is active against most bacteria causing skin infections such as staphylococcus aureus or strains resistant to methicillin or other staphylococcus.
2. Indications and contraindications to the use of Bactronil
Bactronil is indicated for use in the treatment of purulent dermatitis, impetigo, infected open wounds, boils, infectious dermatitis, burns, cellulitis, or exudative venous ulcers. or prevention of infection after skin surgery. However, Bactronil may be contraindicated in cases of hypersensitivity to mupirocin or ointments containing polyethylene glycol or other ingredients of the drug.3. Dosage and how to use Bactronil
The drug is used for both adults and children. When using the drug, it should be applied to the affected skin area up to 3 times per day, and can be used for a maximum of 10 days. During the use of the drug, the affected area can be covered with a bandage if desired to prevent dirt from entering.
Currently, there are no studies to determine the possible effects of long-term use of Bactronil and its safety in children under 3 months of age.
In case the patient accidentally takes the Bactronil drug in excess of the prescribed dose and shows some signs of unwanted side effects, it is necessary to take the patient to the nearest medical facility for assistance. timely medical help to overcome the dangerous situation.
If the patient has missed a dose of Bactronil, the missed dose can be used as soon as he remembers. However, if there is a gap between the missed dose of Bactronil and the next dose, the patient can skip the missed dose and take the next dose. Patients should also be careful not to double the dose of Bactronil because it can cause drug overdose and unwanted side effects that affect the patient's current health.
4. Unwanted side effects and some notes when using Bactronil drug
Bactronil medicine can cause some unwanted side effects during treatment including itching, rash, erythema, dry skin, sensitive skin, swelling, sometimes the patient has a burning sensation, needles or feel pain.
Clinical trials of Bactronil showed some mild side effects localized to the site of application. Skin sensitization reactions to Bactronil have been reported quite rarely. Systemic hypersensitivity reactions may occur when Bactronil topical ointment includes the active ingredient mupirocine.
A few notes when using Bactronil
Bactronil should be used with caution in patients with kidney failure. Bactronil is used to apply to the wound, but the patient should pay attention not to apply Bactronil to the nose, eyes ... In case the patient has a special burn or burns with an area of burn In general, Bactronil should not be used during treatment. Bactronil should not be used concurrently with other medications or should not be mixed with other ointments or creams containing mupirocin. As a result, the concentration of mupirocine may be reduced, and the permeability to the mucosa may also change, resulting in a loss or reduction of the drug's effect. To be safe when using Bactronil, patients can contact their doctor to better understand how to comply with drug use as well as maintain appropriate habits and diets for effective treatment. There are no specific data on the effects of Bactronil on pregnant and lactating women. However, before using Bactronil, patients should carefully weigh the risks and benefits. Although this is important information about Bactronil, it is not a substitute for your doctor's advice. Therefore, before using the patient should discuss with the doctor to have the appropriate indications.
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