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Azforin belongs to the group of drugs for the treatment of upper respiratory tract symptoms, effective in the treatment of diseases such as allergic rhinitis, colds,... Here are detailed information about what Azforin drugs do and Note when using.
1. What is Azforin?
Azforin belongs to the group of drugs for the treatment of upper respiratory tract symptoms, the drug consists of 2 main ingredients: Triprolidine hydrochloride 2.5mg and Pseudoephedrine hydrochloride 60mg. The drug is prepared in the form of tablets, 1 box has 10 blisters x 10 tablets.Pseudoephedrine hydrochloride is a vasoconstrictor, it acts on the sympathetic system with a gradual and prolonged anti-congestive effect, helping to contract the congested mucosa of the upper respiratory tract.
Triprolidine hydrochloride is a substance belonging to the group of antihistamines, it acts on histamine H1 receptors and relieves allergic symptoms such as sneezing, runny nose,... In addition, it also acts on the central nervous system. mild drowsiness.
After taking Azforin, the maximum drug concentration in the blood is reached after about 2 hours. Triprolidine has an anti-allergic effect that reaches a maximum 3 hours after taking the drug, this effect lasts up to 8 hours. The nasal decongestant effect of Pseudoephedrine is maximal 30 minutes after oral administration and is maintained for at least 4 hours.
Elimination: Azforin is eliminated in the urine, the half-lives of Triprolidine and Pseudoephedrine are 3.2 and 5.5 hours, respectively.
2. What does Azforin do?
Azforin drug is effective in the treatment of symptoms of the upper respiratory tract such as runny nose, sneezing, stuffy nose, ... due to simultaneous action by 2 mechanisms: H1 antihistamine reduces hypersensitivity and contraction vessels to reduce congestion and clear nasal passages. Azforin drug is often used in the treatment of cases such as:
Allergic rhinitis: Continuous sneezing, itchy nose, runny nose, ... Vasomotor rhinitis caused by an overreaction of the sympathetic nervous system to other substances. external factors. Symptoms of a cold or flu.
3. Dosage, how to use Azforin
How to use: Azforin is taken orally with a full glass of water, you can take it before or after eating, because food does not affect the effect and absorption of the drug. Do not eat a lot of acidic foods such as oranges, lemons, grapefruits, tomatoes... because the drug is eliminated faster in the acidic environment.
Dosage: Azforin is used as prescribed by a doctor, but you can refer to the manufacturer's recommended dose below:
For children over 12 years old and adults: Take 1 tablet / time Drink 3 times a day. For patients with hepatic and renal impairment: The drug is metabolized by the liver and eliminated, so for severe liver failure, moderate to severe renal impairment should be used with caution, the dose may be reduced at the start of treatment. . Please inform your doctor about your medical condition to be considered when using the drug. For the elderly: There are currently no specific studies on the dose of Azforin in the elderly, so cases of 60 years and older should take the drug according to the dose prescribed by the doctor.
4. Contraindications of Azforin
Azforin should not be used in the following cases:
People with a history of allergy or hypersensitivity to any of the ingredients in Azforin. Azforin should not be used in children under 6 years of age. People with a history of angle-closure glaucoma, severe hypertension or severe coronary artery disease, people with acute asthma attacks should not use this medicine. Therefore, please inform your doctor about the diseases you have been suffering from so that you can prescribe the right medicine. Azforin is contraindicated in those who are using or have used within the last 2 weeks of the MAO tricyclic antidepressant group and absolutely must not combine Azforin with Furazolidone. Therefore, you need to inform your doctor about the medicines you are using for advice on choosing the right medicine.
5. Undesirable effects when using Azforin
When using Azforin you may experience unwanted effects with frequency such as:
Common: Drowsiness, dizziness and dizziness. Therefore, you should not take the drug while you have to work or have to concentrate very hard, because the drug can affect work performance. In rare cases, hallucinations or sleep disturbances may subside or disappear when you stop using the drug. Less frequent: An itchy, burning rash, dry mouth/nasopharynx. In men, urinary retention may occur in patients with a history of prostate enlargement. If you are in the above case, you should inform your doctor about your medical condition to be closely monitored when taking the drug. If you experience any unwanted symptoms while using Azforin, tell your doctor for advice on how to deal with the symptoms you experience.
6. Notes when using Azforin
When using Azforin you should note the following points:
Tell your pharmacist or doctor if you are taking the following drugs: Diet pills, tricyclic antidepressants, Amphetamines, Methyldopa, drugs alpha adrenergic blocker, beta-adrenergic blocker,... Azforin has a side effect of causing drowsiness, so it should not be used by people who drive or operate machinery. Azforin is excreted in small amounts in breast milk, but no studies have clearly shown the effect of the drug on the nursing infant. If you are breast-feeding, tell your doctor to be considered before using the drug. There are no clear studies on the effects of the drug on the fetus, so if you are pregnant, tell your pharmacist or doctor to weigh the benefits and risks of using Azforin before making a decision. treatment determination. You need to inform your doctor about medical history, especially diseases such as hypertension, prostate enlargement, liver failure, kidney failure, cardiovascular diseases, glaucoma .... You should Monitor blood pressure regularly while taking Azforin because Pseudoephedrine in the drug acts on the sympathomimetic system can cause an increase in blood pressure. Above is information about uses, dosage and precautions when using Azforin. If you have any questions about Azforin, you can contact your pharmacist or doctor for advice.
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