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Drug Axcel Cephalexin-250 is a broad-spectrum antibiotic with anti-bacterial effect in many cases such as respiratory tract infections, urinary tract infections, obstetric and gynecological infections... Before using Axcel Cephalexin- 250 patients need to read the instructions carefully before use.
1. What are the uses of Axcel Cephalexin-250?
1.1. What is Axcel Cephalexin-250? Axcel Cephalexin-250 is an antibiotic of the Cephalexin group. Axcel Cephalexin-250 medicine includes the following ingredients:
Main active ingredients: Cephalexin monohydrate equivalent to Cephalexin 500mg Excipients include: Lactose, Sodium lauryl sulphal, Magnesium stearate, talc powder. The drug is prepared in the form of hard capsules size 2 pink or dark red. Axcel Cephalexin-250 capsules are indicated for use in both children and adults.
1.2. What is Axcel Cephalexin 250 used for? Cephalexin is a 1st generation cephalosporin antibiotic with moderate bactericidal effect, active against gram-positive bacteria such as streptococcus, staphylococcus, pneumococcus (except methicillin-resistant streptococcus). Cephalexin is also active against some gram-negative bacteria such as E.coli, Klebsiella pneumoniae, Proteus mirabilis and Shigella. There are resistant strains: Enterococcus, methicillin-resistant Staphylococcus, Proteus with positive indole reaction, Enterobacter, Pseudomonas aeruginosa, Bacteroides.
Axcel Cephalexin 250 is completely absorbed orally.
Axcel Cephalexin 250 is prescribed by doctors to treat infections caused by susceptible bacteria:
Respiratory tract infections: Acute and chronic bronchitis, otitis media, mastoiditis, inflammation sinusitis, tonsillitis and pharyngitis. Urinary tract infections, acute and chronic pyelonephritis and cystitis, prevention of recurrent urinary tract infections. Gynecological and obstetric infections. Skin, soft tissue and bone infections. Gonorrhea and syphilis (when penicillin is not suitable). In dentistry: Bacterial gingival infections, temporary replacement of preventive therapy with penicillin for patients with heart disease requiring treatment for dental disease.
2. How to use Axcel Cephalexin-250
2.1. How to take Axcel Cephalexin-250 Axcel Cephalexin 250mg is made in the form of hard capsules, so it should be taken orally Take the medicine with a sufficient amount of filtered water. Do not break, chew or crush, but swallow the whole tablet. Do not mix the drug with any other mixture. Take medications as directed by your doctor 2.2. Dosage of the drug Axcel Cephalexin-250 Adults:
Many infections in adults respond to doses of 1g - 2g / day in divided doses. However, in most cases of infections, the following dosages are effective:
Adults and children over 12 years of age 500mg x 3 times/day. In some cases to make it more convenient for patients, especially those who often have to travel, the daily dose can be divided into 2 times, for example, people with urinary tract infections can take 1g dose. x 2 times/day. In case of severe infections or infections less sensitive to the drug. Dosage should be increased to 1g x 3 times/day or 1.5g x 4 times/day. Children:
The usual recommended dose is 25-60mg/kg/day. In severe infections, the dose should be increased to 100 mg/kg/day (maximum 4 g/day). Children from 3 to 6 years old 125 - 250mg x 4 times / day or 250 - 500 mg x 2 times / day. Children from 7 to 12 years old 250 - 500mg x 4 times/day or 500mg - 1g x 2 times/day. Duration of treatment:
In most cases of acute infection, treatment should continue for at least 2 days after the symptoms of infection have resolved. In cases of chronic infections, recurrent or complicated urinary tract infections, the duration of treatment is 2 weeks (the dose is 500mg x 4 times/day).
Patients with renal impairment:
Dosage should be halved for patients with severe renal impairment (creatinine clearance < 10 mL/min). The maximum recommended dose (6g/day for adults, 4g/day for children) should be reduced by 50% for patients with mild renal impairment, by 75% for patients with moderate renal impairment and by 87.5% for patients with moderate renal impairment. in patients with severe renal impairment.
In cases of intermittent dialysis, 500 mg should be added after each dialysis in adults and 8 mg in children.
Dealing with missed doses:
This is a medical treatment, so you should limit missed doses by setting a notice of the time to take the medicine. If you miss a dose, take Axcel Cephalexin 250mg as soon as you remember. However, if it is too short to take the next dose, skip the missed dose and continue taking it as scheduled. Do not take a double dose to replace the missed dose. Treatment in case of overdose:
If there are any abnormal signs during the time of taking the drug, immediately notify the treating doctor for timely treatment. Serum concentrations of cephalexine can be reduced to a large extent by hemodialysis or peritoneal dialysis.
3. Contraindications of Axcel Cephalexin-250
Patients who are allergic to the main active ingredient cephalexine or any of the excipients listed above of Axcel Cephalexin 250mg
4. Notes when using Axcel Cephalexin-250
Caution should be exercised when Axcel Cephalexin 250mg is used in patients with known hypersensitivity to penicillin. Do not use in people with a history of anaphylaxis due to penicillin or other serious reactions. Cephalexine is generally well tolerated in penicillin-allergic patients, although a very small number of cross-reactions have occurred. As with antibiotics that are eliminated primarily by the kidneys, when renal function is impaired, the dose of cefalexine should be reduced appropriately. During treatment with cephalexin may give a false positive reaction in urine sugar test and Combs test. Use with caution in patients with renal impairment. Pseudomembranous colitis has been reported to occur from mild to life-threatening with most antibiotics, including cephalexin. Therefore, caution should be exercised when symptoms of diarrhea are observed in patients following administration of cephalexin. Prolonged use of cephalexin may cause overgrowth of non-susceptible microorganisms, therefore caution should be exercised. If superinfection occurs during treatment, appropriate therapeutic measures should be instituted. Cephalexine may interfere with the alkaline picrate creatinine test, giving a falsely high result, however elevated levels are most likely to occur. as clinically unimportant. Cephalexin reduces the effectiveness of oral contraceptives containing oestrogen. Concomitant use with probenecid reduces the elimination of cephalexin. Concomitant use with nephrotoxic drugs such as aminoglycoside antibiotics may increase the risk of nephrotoxicity of cephalexin. Concomitant use with the diuretic furosemide may increase nephrotoxicity.
5. Side effects of the drug Axcel Cephalexin-250
During the use of Axcel Cephalexin-250, patients may experience some of the following side effects: Diarrhea, nausea.
More rarely can be mentioned as:
Blood: Eosinophilia. Skin: Rash, urticaria, itching. Liver: Reversible increase in liver transaminases. It is best when experiencing side effects on the patient should notify the doctor, pharmacist for advice on the most appropriate plan.
In summary, Axcel Cephalexin-250 is a broad-spectrum antibiotic that is effective in fighting respiratory tract infections, urinary tract infections, obstetric and gynecological infections... more positive and safer treatment results for the patient's own health.
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