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Avasboston is a drug whose main ingredient is Atorvastatin indicated in the treatment of high cholesterol, mixed dyslipidemia, and prevention of coronary heart disease. Read the article below to get more useful information about the use of Avasboston.1. What does Avasboston do?
Avasboston drug containing Atorvastatin is indicated for treatment in the following cases:
Reduce total cholesterol, LDL-cholesterol; apolipoprotein B and triglycerides, and to increase HDL-cholesterol in patients with primary hypercholesterolemia Beta lipoprotein dysregulation who has not responded adequately to diet. Reduction of total cholesterol, and LDL-cholesterol in patients with homozygous familial hypercholesterolemia on diet. Contraindications for use of Avasboston:
People with hypersensitivity to HMG-CoA reductase inhibitors People with advanced liver disease, or persistent elevations in serum transaminases of unknown cause. Pregnant and lactating women.
2. Avasboston's Usage
2.1. How to take Avasboston Avasboston is available as a film-coated tablet, which should be taken orally. This medicine can be taken at any time of the day, regardless of meals. Avasboston Tablets should be swallowed whole with a sufficient amount of filtered or boiled water. Patients need to apply a low cholesterol diet before taking Avasboston and maintain it for the entire time taking the drug. Since cholesterol synthesis in the liver occurs mainly at night, taking the drug in the evening will increase its effectiveness. 2.2. Dosage of Avasboston It is recommended that treatment be initiated at a dose based on needs, and individual patient response, increasing or decreasing the dose at intervals of not less than 4 weeks, until cholesterol levels are reached. LDL is desired, or when the maximum dose is reached.
Initial dose: 10mg, once a day. Maintenance dose: 10mg to 40mg per day. If necessary, the patient can increase the dose, but not more than 80mg per day. 2.3. Treatment of missed dose/overdose If a dose is missed, take the dose as soon as you remember it. Usually, the drugs can be taken more slowly, from 1 to 2 hours than the time prescribed by the doctor. Except for those drugs that have strict regulations on the duration of taking them. However, if it is too far from the missed dose and it is close to the next dose, the patient should skip the missed dose of Avasboston, and never double the dose. Because it may cause danger to the health of the user.
There are no special symptoms with an overdose of Avasboston. If an overdose occurs, treat symptomatically and provide support as necessary. Because of its high protein binding in plasma, dialysis and hemodialysis are unlikely to significantly increase clearance of atorvastatin.
3. Notes when using Avasboston
Before treatment with Avasboston, care should be taken to exclude the causes of secondary dyslipidemia and measure lipid indices. During co-administration with HMG-CoA reductase inhibitors, if creatine kinase is elevated, myositis develops, or serum liver enzyme levels rise to 3 times the upper limit of normal, the dose should be reduced. , or discontinue treatment. Use with caution in patients with liver dysfunction, patients with heavy alcohol consumption. Patients should have a reasonable diet before taking treatment with the drug, should maintain this diet throughout the course of treatment with the drug.
4. Avasboston side effects
In general, statins are well tolerated, with a lower discontinuation rate compared with other lipid-lowering agents. However, patients may still experience unwanted side effects such as:
Common: Diarrhea, constipation, bloating, or abdominal pain, and nausea, headache, or dizziness, eyes blurred vision, insomnia, weakness, and muscle and joint pain. Uncommon: Myopathy, skin rash, rhinitis, sinusitis, and pharyngitis, cough. Rare: Myositis, rhabdomyolysis leading to acute renal failure secondary to myoglobinuria. Patients need to inform the specialist doctor if they experience any unwanted effects while using the drug.
5. Avasboston drug interactions
Anticoagulants and indandione in combination with Avasboston will increase bleeding time, or prothrombin time. Prothrombin time should be monitored in patients receiving concomitant anticoagulant cyclosporine; erythromycin; gemfibrozil, and immunosuppressants; Niacin: Concomitant use increases the risk of myopathy. Digoxin: Co-administration with Avasboston causes a slight increase in serum digoxin concentrations
6. How to store Avasboston
The drug is stored Avasboston medicine at room temperature, in a cool and dry place, avoiding direct sunlight. Because the high temperature can damage the ingredients in the medicine. Also, do not leave the medicine near the place where there are devices that when used emit a higher temperature than room temperature such as: TV, or refrigerator, microwave oven, stove... Before using the medicine, you should carefully check the expiry date of the medicine. medicine. Absolutely do not use Avasboston after the expiry date printed on the package.
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