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Ausdroxil contains the main ingredient Cefadroxil, which is an antibiotic belonging to the 1st generation cephalosporin group. Let's learn about the effects of Ausdroxil and how to use this drug in the article below.
1. What is Ausdroxil?
Ausdroxil has the main ingredient Cefadroxil, which is an antibiotic belonging to the 1st generation Cephalosporin group. Ausdroxil is manufactured in the form of a vial of powder for oral suspension.
2. What does Ausdroxil do?
Ausdroxil is indicated in the treatment of mild and moderate infections caused by susceptible bacteria:
Upper and lower urinary tract infections: acute pyelonephritis, chronic pyelonephritis, cystitis, inflammation urethritis, vaginitis, gynecological infections. Upper and lower respiratory tract infections: sinusitis, tonsillitis, pharyngitis, laryngitis, acute bronchitis, chronic bronchitis, bronchopneumonia, lobar pneumonia, lung abscess. Skin and soft tissue infections such as: lymphadenitis, abscess, ulceration due to prolonged lying, mastitis, erysipelas, boil disease.
3. Usage and dosage of the drug Ausdroxil
Ausdroxil is prepared as a powder for oral suspension. Before use, shake the powder in the vial, add cooled boiled water to the mark on the bottle and close the cap. Shake the vial well for 2 minutes to make a suspension containing the drug. Box of 1 vial of powder medicine after mixing into 60ml of oral suspension. The reconstituted suspension should be used within 4 days of reconstitution and should be stored in the refrigerator. If you have any questions about how to take the medicine, contact your doctor or pharmacist for more information about Ausdroxil.
Dosage of Ausdroxil:
The drug, after being mixed into a suspension, each 5ml (one teaspoon) contains 125mg Cefadroxil. Dosage of Ausdroxil drug is adjusted according to age, weight, disease condition. Therefore, patients should follow the instructions of the treating doctor, do not arbitrarily increase or decrease the dose of the drug. The following is a reference dose of Ausdroxil:
Adults and children (over 40 kg): Take 4-8 teaspoons each time x 2 times/day.
Children (under 40kg):
Children < 1 year old: Take 25-50mg/kg of child's weight/day, divided into 2-3 times. Children from 1-6 years old: Drink 2 teaspoons each time x 2 times/day. Children from > 6 years: Drink 4 teaspoons each time x 2 times/day. Elderly: Adjust dose according to creatinine clearance such as renal failure.
People with renal failure: Can be treated with a starting dose of 500mg-1000mg Ausdroxil. But the next dose can be adjusted according to the following table:
4. Ausdroxil overdose and how to handle it
Symptoms of acute Ausdroxil overdose: Nausea, vomiting, diarrhea. Patients may experience neuromuscular hypersensitivity, convulsions, especially in patients with renal failure.
Management of overdose should consider the possibility of overdose of many drugs, drug interactions and the condition of the patient. If the patient has any symptoms of overdose, they should immediately contact a doctor or go to a medical facility for timely treatment. Mainly symptomatic supportive treatment, respiratory protection, intravenous fluids are the first priority, gastric lavage can be given if the patient arrives at a health facility before 6am.
5. Contraindications of the drug Ausdroxil
Ausdroxil should not be used in patients with a history of allergy to cephalosporin antibiotics and other ingredients of Ausdroxil.
6. Ausdroxil side effects
When using Ausdroxil, you may experience unwanted effects as follows:
Common side effects: Abdominal pain, diarrhea, nausea, vomiting. On the Liver: increased liver enzymes, reversible upon discontinuation of the drug.
Uncommon side effects:
Blood: Eosinophilia. On Skin: Skin rash, rash, urticaria, pruritus Urinary-genital system: Testicular pain, candidiasis, vaginitis, genital itching. Rare side effects:
Systemic: Fever, anaphylactic reactions. Blood: neutropenia, thrombocytopenia, hemolytic anemia. Digestive system: Pseudomembranous colitis, digestive disorders. On the Liver: Cholestatic jaundice, hepatitis. Skin: Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome). When the patient appears to have any unwanted effects when using Ausdroxil, it is necessary to immediately contact a doctor or go to a medical facility for timely treatment.
7. Precautions when using Ausdroxil
When using Ausdroxil, caution should be exercised in the following cases:
Ausdroxil is excreted by the kidneys, so it should be used with caution in patients with renal failure. Before and during treatment with Ausdroxil, patients with renal impairment or suspected renal failure should be clinically monitored and appropriate laboratory tests performed. Because of cross-reactivity between penicillins and cephalosporins, patients should inform their doctor about their allergy history to penicillins, penicillins or other drugs, if any, to which they are currently taking, before starting treatment . Long-term use of Ausdroxil may cause overgrowth of non-susceptible strains of bacteria, causing drug resistance. Therefore, it is necessary to monitor the patient carefully, stop using the drug if there is an opportunistic infection, bacterial superinfection. Patients were diagnosed with pseudomembranous colitis when using broad-spectrum antibiotics, which can cause gastrointestinal disturbances and severe diarrhea. Therefore, clinical monitoring and appropriate testing should be performed in this patient. Caution should be exercised when administering the drug to neonates and premature infants, due to limited experience with Ausdroxil in this population. Pregnancy: There have been no reports of harmful effects on the fetus, the safe use of Ausdroxil during pregnancy has not been established. Therefore, Ausdroxil should only be used during pregnancy under the direction of a specialist when absolutely necessary. Lactation: Ausdroxil is excreted in breast milk in low concentrations with no effect on the nursing infant. However, breastfeeding women taking the drug must follow the doctor's prescription to avoid an overdose. For drivers and operators: The drug can cause headache, agitation (rare). Therefore, when taking the drug, care should be taken when driving and operating machinery. Ausdroxil is indicated in the treatment of mild and moderate infections caused by susceptible bacteria. However, antibiotic resistance is very common in patients. To ensure effective treatment and avoid unwanted effects, users need to strictly follow the instructions of a doctor, professional pharmacist.
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