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Asmolex 80 belongs to the group of cardiovascular drugs, in tablet dosage form. The drug contains the main ingredient is Sotalol hydrochloride 80mg, packed in box of 4 blisters x 10 tablets. Complying with the indications, the dose of Asmolex 80 will help patients improve the effectiveness of treatment and avoid unwanted side effects.
1. What are the effects of Asmolex 80?
The active ingredient Sotalol in Asmolex 80 has an antiarrhythmic effect through prolonging the duration of potential action on the myocardium. This results in a longer effective resistance interval. Some studies suggest that the electrophysiological effects of group III are achieved mainly by blocking potassium channels, while the active ingredient Sotalol has electrophysiological, pharmacological and pharmacokinetic properties of both groups. II and III. Sotalol is unique in that the pharmacology of Asmolex 80 is affected by its symmetry. The group III activity of Sotalol is due to the D-isomer (currently only available in Europe), while the beta-blocking activity of Sotalol is due to the l-isomer.Currently, Asmolex 80 is used to treat the following conditions:
Severe ventricular tachycardia. Prophylaxis of recurrent atrial fibrillation after electroconvulsive defibrillation. Prevention of paroxysmal atrial fibrillation. CKD .
2. Contraindications of Asmolex 80
Asmolex 80 should not be used in the following cases:
People with a history of hypersensitivity to the components and excipients of Asmolex 80. People with grade IV decompensated heart failure or acute myocardial infarction. People with shock, sinoatrial block, second-degree atrioventricular block, heart rate <50 beats/min, sinus node failure or prolonged QT interval. People with hypokalemia or low blood pressure. People with late stage peripheral fluid disorders, metabolic acidosis and respiratory obstruction. Caution when using Asmolex 80 for people:
There is a history of drug allergy. Having kidney failure. Are on a strict diet. Have diabetes. The elderly, children and pregnant or lactating women. Drivers and machine operators.
3. Dosage and how to use Asmolex 80
How to use: Asmolex 80 is taken orally. Patients should swallow Asmolex 80 tablets whole with water. Asmolex 80 tablets should not be chewed, crushed or broken as this can increase the side effects when taken.
Reference dosage:
Treatment of severe ventricular tachycardia 1 tablet x 2 times/day. If necessary, the dose can be increased by 1 tablet x 3 times/day or 2 tablets x 2 times/day. Maximum dose of 6 Asmolex 80 tablets / day x 2-3 times. Prophylaxis of recurrent atrial fibrillation after defibrillation with electric shock: 1 tablet x 2-3 times/day. Prophylaxis of paroxysmal atrial fibrillation 1 tablet x 2 times. Maximum dose 2 tablets x 2 times/day. People with kidney failure ClCr 10-30mL/min: Need to reduce 1⁄2 dose of Asmolex 80. If ClCr <10mL/min, reduce by 1⁄4 dose of Asmolex 80. Note: The dose of Asmolex 80 above is for reference only. The specific dose of Asmolex 80 depends on the condition and the progression of the disease. To get the right dose of Asmolex 80, patients should consult their doctor or healthcare professional.
4. Asmolex 80 . drug interactions
Asmolex 80 may have an interaction reaction if used concurrently with:
Veparamil; Drugs Diltiazem ; Drugs Nifedipine; Norepinephrine drug; MAO; Insulin ; Diabetes medication. To avoid interactions, before being prescribed Asmolex 80, patients should inform their doctors about all the drugs they are using, including functional foods. The doctor will base on that to prescribe the appropriate Asmolex 80.
5. Side effects of Asmolex 80
At therapeutic doses, Asmolex 80 was well tolerated. However, during the use of Asmolex 80, patients may still experience side effects such as:
Common:
Headache; Tired; Dizzy; Feeling cold; Numb limbs. Rarely:
Gastrointestinal disturbances; Skin allergies; Lower blood pressure; Slow heart rate. This is not a complete list of Asmolex 80 side effects. Therefore, if the patient notices any unusual signs of the body while taking Asmolex 80, please inform the doctor for advice. .
5. Notes when using Asmolex 80
Asmolex 80 should be used with caution when driving or operating machinery. In the event of a missed dose of Asmolex 80, it is advisable to make up for it as soon as possible. However, if it is almost time for the next dose, skip the missed dose of Asmolex 80 and use a new dose. When using Asmolex 80 drug overdose, the patient should stop the drug immediately and go to the nearest medical facility for timely treatment. Asmolex 80 should be used with caution in people with severe liver and kidney failure. Absolutely do not use when Asmolex 80 has signs of discoloration, mold, watery or expired. Above is all information about Asmolex 80, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Asmolex 80 is a prescription drug, patients need to use the drug as prescribed by the doctor, absolutely do not self-treat at home.
