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Antirizin drugs have the main active ingredient is Cetirizine and other excipients in a sufficient amount. This is a drug with anti-allergic effect and used in cases of hypersensitivity.
1. What is Antirizine?
What is Antirizine? Antirizin medicine has the main active ingredient Cetirizine and other excipients in a sufficient amount. This is a drug with anti-allergic effect and used in cases of hypersensitivity.
Antirizin is made in the form of tablets, suitable for direct oral use. Packing is box of 10 blisters, each blister contains 10 tablets.
1.1. Pharmacokinetics of Antirizin Active ingredient Cetirizine is a potent antihistamine with antiallergic activity, but does not cause drowsiness at pharmacologically therapeutic doses. Active ingredient Cetirizine has a selective antagonistic effect at H1 receptors, but has almost no effect on other receptors, so it almost does not cause Acetylcholine antagonistic effects and has no Serotonin antagonistic effects. Cetirizine inhibits the early stages of histamine-mediated allergic reactions and also reduces the migration of inflammatory cell types and the release of mediators in the late stages of allergic reactions.
1.2. Pharmacokinetics of Antirizin Peak blood concentrations are at 0.3 micrograms/ml 30 to 60 minutes after a single oral dose of 10 mg. The plasma half-life is approximately 11 hours. Absorption of Antirizin was not altered between individuals. The mean renal clearance is 30 ml/min and the elimination half-life is approximately 9 hours. The active substance Cetirizine is strongly bound to plasma proteins (about 93%).
2. What are the effects of Antirizine?
Antirizin is used in the treatment of the following diseases:
Treatment of seasonal allergic rhinitis, year-round allergic rhinitis with accompanying symptoms such as sneezing, runny nose, postnasal discharge, Red eyes with watery eyes. Treatment of chronic idiopathic urticaria with symptoms such as pruritus accompanied by a rash.
3. Usage and dosage of Antirizin
Antirizin is made in the form of tablets, suitable for direct oral use.
Treatment dose for adults and children over 12 years old: The initial treatment dose is 5 - 10 mg/day, depending on the level and can be used for a long time. Treatment dose for adults over 65 years old: the dose is 5 mg/day Note: Patients need to apply the exact therapeutic dose of Antirizin indicated on the package, drug instruction sheet or doctor's instructions. treating doctor. Patients absolutely do not arbitrarily calculate, apply or change the prescribed dose.
4. In case of overdose, missed dose and treatment
In case of overdose: Prescription drugs require a prescription from the treating physician or clinical pharmacist. Over-the-counter medicines require a package insert from the drug manufacturer. You need to actively read carefully and follow the exact dose indicated on the prescription or drug leaflet. When using an overdose of Antirizin, it is necessary to stop taking it, immediately notify the doctor or pharmacist when there are unusual manifestations.
In case of missed dose: Usually, drugs including Antirizin can be taken within 1-2 hours compared to prescribed in the prescription. However, if the time of taking the drug is too far from the time it should be taken, it should not be taken to make up for it, because it can be dangerous to the body. You need to pay attention to correct compliance or consult your treating doctor before deciding to use the drug.
5. Undesirable effects of the drug Antirizin
Common undesirable effects of Antirizin, including: The most common side effect is somnolence. The incidence is dose dependent in the clinical setting. In addition, the drug Antirizin also causes fatigue, dry mouth, sore throat, dizziness, headache, nausea.
Uncommon side effects of Antirizin, including: anorexia or increased appetite, urinary retention, flushing, increased salivation.
Rare adverse effects of Antirizin, including: hemolytic anemia, decreased platelet count, severe hypotension, anaphylaxis, hepatitis, cholestasis, glomerulonephritis.
Usually, the side effects or unwanted effects of Antirizin will go away when the drug is stopped. If you experience rare side effects that are not listed in the instructions for use, you need to actively inform your doctor.
6. Antirizin drug interactions
To date, there have been no significant interactions of Antirizin with other drugs. The clearance of active substance Cetirizine may be slightly reduced when co-administered with 400 mg of Theophylline.
7. Some notes when using Antirizin
Notes and cautions before using Antirizin in the treatment of diseases are as follows:
It is necessary to adjust the treatment dose for people with moderate or severe renal impairment and people on hemodialysis. It is necessary to adjust the therapeutic dose of the drug in patients with hepatic impairment. Pregnancy: Although Antirizin is not teratogenic in laboratory animals, there have been no adequate studies in pregnant women, so it should not be used while you are pregnant. Lactation: Cetirizine active ingredient has a risk of being excreted in milk, so women who are breast-feeding should not use Antirizin. Effects on drivers, operating machines: In some people using Antirizin, there is a phenomenon of drowsiness. Therefore, caution should be exercised when driving, or operating machinery, because of the risk of danger. Antirizin medicine has the main active ingredient Cetirizine and other excipients in a sufficient amount. This is a drug with anti-allergic effect and used in cases of hypersensitivity. Patients need to strictly follow the instructions of the doctor, pharmacist to ensure the highest treatment effectiveness, and at the same time avoid side effects, dangerous drug interactions.
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