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Amphadase is a protein, given as an injection to enhance the absorption of other drugs when used together. Let's find out the uses and notes when using Amphadase through the article below.
1. Uses of Amphadase
Amphadase has the active ingredient hyaluronidase, which is formulated as an injection. The dosage forms are lyophilized powder for injection of 150 IU or 1500 IU (international units) or solution for injection of 150 IU/ml.
Amphadase (Hyaluronidase) is a proteolytic enzyme, Hyaluronidase has the effect of hydrolyzing hyaluronic acid (this is one of the main components that help bind connective tissue cells together, preventing fluid from diffusing through the tissue). decreased tissue permeability). When using Amphadase to break down hyaluronic acid, it helps to increase tissue permeability to fluids or drugs. Therefore, the drug is used to treat subcutaneous drainage, promoting the elimination of excess fluid or blood due to extravasation. Hyaluronidase also helps tissue increase tissue permeability to drugs that support rapid absorption, reduce discomfort when using drugs by subcutaneous or intramuscular injection with large amounts of drugs, which cannot be administered intravenously. circuit. In addition, Amphadase is also used to help contrast dyes in the body show up more clearly on certain types of X-rays.
2. How to use Amphadase
How to use: Amphadase is injected under the skin, into a muscle or into other body tissues. You will be given an injection by a medical staff. Note that amphadase should not be injected intravenously.
Dosage: Used depending on the purpose of treatment, age. Your doctor will prescribe the right dose for you.
Note the symptoms of overdose: Edema or urticaria at the injection site, erythema, chills, nausea and vomiting, dizziness, tachycardia and hypotension. There is no specific drug to treat overdose, you need to be treated for symptoms accordingly.
3. Side effects when taking Amphadase
Possible side effects of taking Amphadase include:
Get emergency medical help if you have signs of a serious allergic reaction to Amphadase such as: hives; shortness of breath ; swelling of the face, lips, tongue, or throat. Stop taking the medicine and call your doctor at once if you have any of these side effects of Amphadase such as: Swelling in the hands, feet, or swelling in other body areas; severe pain, swelling, itching, or redness at the injection site. The above is not a complete list of side effects and other side effects that may occur when taking this medicine. If you experience the above side effects or other effects that may be caused by taking the drug, you should inform your doctor for appropriate indications.
4. Notes when using Alphadaze
Do not use when the patient has a history of hypersensitivity to hyaluronidase. Do not administer hyaluronidase intravenously. Do not inject around or inject into areas of infection, acute inflammation or malignancy. Do not use directly on the cornea. Do not use to reduce swelling caused by animal or insect bites.
Before using the drug you are often tested on the skin to know if you are allergic to the drug or not. Tell your doctor if you have other medical conditions or are taking other medications.
The level of safety for pregnant and lactating women has not been tested for safety and effectiveness. Should only be used when absolutely necessary.
Serious drug interactions can occur when certain drugs are used together with Amphadase. Before taking Amphadase, tell your doctor if you are taking any of the following medicines: diuretic furosemide (Lasix); phenytoin (Dilantin); sedative or anxiety medication (such as Valium, Xanax, Tranxene).... When these drugs are taken together, they can cause more severe side effects.
Above is some information about Amphadase drug, hope you already know what Amphadase is, how it works and how to use it.
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Source: drugs.com