This is an automatically translated article.
Amlothope is a drug belonging to the cardiovascular group. It is commonly used to control essential hypertension and to treat angina pectoris. To use Amlothope safely and achieve the best treatment effect, patients need to know the detailed information about this drug below.
1. What is Amlothope?
Amlothope is a pharmaceutical product manufactured by JSC "Makiz-Pharma" of Russia and registered by Vinacare Pharmaceutical Joint Stock Company, Vietnam.
Amlothope belongs to the group of cardiovascular drugs with the active ingredient Amlodipine besilate 5mg. It is indicated for the control of essential hypertension, for the treatment of stable angina and vasospastic angina.
Amlothope medicine is prepared in the form of uncoated tablets, packed in a box of 1 blister x 30 tablets, each tablet contains 5mg of amlodipine and other excipients just enough.
2. What are the uses of Amlothope?
2.1. The active ingredient of the drug Amlodipine is a calcium antagonist of the Dehydropyridine group. The drug has the ability to inhibit the influx of calcium through the membrane into the cardiac muscle cells and smooth muscle of the blood vessel wall by blocking the slow calcium channels of the cell membrane. Thanks to this effect, the arterioles decrease, thereby reducing peripheral resistance and leading to hypotension.
In addition, the drug also has antianginal effects mainly by dilating peripheral arterioles and reducing cardiac afterload. The myocardial energy consumption and oxygen demand are reduced because the drug does not induce reflex tachycardia.
2.2. Indications for use of Amlothope Amlothope is indicated in the following cases:
Helps control essential hypertension. Treatment of stable angina and treatment of vasospastic angina 2.3. Contraindications Amlothope is contraindicated in the following cases:
Patients with hypersensitivity to Amlodipine or dihydropyridine derivatives or other excipients included in the drug's formula. People who are pregnant or are breastfeeding.
3. How to use and dosage
Amlothope is only used when prescribed by a qualified doctor. Therefore, the patient should take the medicine according to the instructions and the correct dose prescribed by the doctor.
3.1. How to take Amlothope by mouth directly with 1 amount of purified or boiled water. When taking Amlothope, the patient should swallow the tablet whole, do not crush, break, disperse or chew because it can change the ingredients in the drug. Do not drink Amlothope with alcohol, beer, alcoholic beverages, tea or carbonated drinks, bottled soft drinks will affect the effect of the drug. 3.2. Dosage Adults: The initial dose for treatment of hypertension and angina pectoris is usually 5 mg once daily. Dosage may be increased to a maximum of 10 mg once daily depending on patient response. For patients with hepatic impairment, the recommended dose is lower, no dose adjustment is necessary when co-administered with thiazide diuretics or ACE inhibitors. To have the most specific and appropriate dose of Amlothope, the patient should consult with the treating doctor. Absolutely do not adjust or change the dose of the drug without consulting your doctor.
4. Side effects
Amlodipine is well tolerated with few side effects or side effects are usually mild to moderate and pass quickly.
Some common side effects when taking Amlothope are: Headache, dizziness, fatigue, edema, nausea and palpitations. Very rarely, the patient experiences itching, weakness, or cramps.
Note: When experiencing the above side effects, the patient should immediately call a doctor or medical professional for advice on effective and safe management. In case of danger, prolonged side effects or other abnormalities when taking Amlothope, the patient can be taken to a medical facility for examination and timely treatment.
5. Drug interactions
Amlothope may interact with some medications, affecting the effectiveness of existing medications or increasing side effects.
Therefore, in order to avoid drug interactions that affect the process and effectiveness of Amlothope use, patients should list and inform their doctors about the drugs, herbs, and supplements they are taking. From there, the doctor can advise, adjust the dose or prescribe another alternative medicine that is suitable and safe for the patient.
Some drugs that may interact with amlodipine include:
Non-steroidal anti-inflammatory drugs: Amlodipine is safe to be used with non-steroidal anti-inflammatory drugs, but may reduce Amlodipine's hypotension, especially Indomethacin, by inhibiting its synthesis. Prostaglandin in the kidney and causes Na+ and water retention. Estrogen: Causes water retention, so it tends to increase blood pressure. Sympathomimetic drugs will reduce the antihypertensive effect of the active ingredient Amlodipine.
6. Notes and cautions
In order for Amlothope medicine to be fully effective in treating the disease and ensure safety when used, patients also need to pay attention and be extra cautious about the following issues:
Need to use the drug according to the indications and instructions. by a qualified doctor, do not arbitrarily adjust the dose of the drug, stop the drug, or stop taking the medication course without the doctor's prescription. Use with caution in patients with aortic stenosis, liver failure and congestive heart failure. The active ingredient of Amlothope does not cross the dialysis membrane. The drug is not recommended for pregnant or lactating women because it can affect the fetus and young children.
7. Forgetting and Overdosing
Missed dose: If you forget to take a dose of Amlothope, take it on the same day as you remember as soon as possible. If it is almost time for the next dose, skip the missed dose and take the next scheduled dose. Do not take 2 doses at the same time to avoid increased side effects, overdose. Overdose: When there are signs of suspected Amlothope overdose or abnormality, the patient should stop taking the drug and call the doctor for specific advice, or take the patient to a nearby medical facility for examination and treatment. emergency measures and timely treatment.
8. How to store medicine
Amlothope should be stored in a dry place, away from sunlight, away from moisture and at a temperature not exceeding 30 degrees Celsius. Keep Amlothope out of reach of children and pets. For Amlothope that is no longer in use, the medicine must not be flushed under the household tap and must not be thrown into the toilet. Collect and dispose of medical waste according to the instructions of your doctor, manufacturer or waste disposal company. Above is all information about Amlothope drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Amlothope is a prescription drug, patients absolutely cannot buy and treat at home because they may experience unwanted side effects.
