This is an automatically translated article.
Amlibon medicine contains Amlodipine 10mg in the form of besylate salt. The drug is indicated in the treatment of hypertension, angina... The drug may cause some unwanted side effects, so patients should carefully read the instructions for use and follow the doctor's instructions. doctor.
1. Mechanism of action of the drug Amlibon
The amlodipine component in Amlibon is a DIhydropyridine derivative with calcium antagonist activity in smooth muscle cells. This derivative binds to the N site on the L-type calcium ion transport channel, which reduces the amount of calcium ions entering the cell. Thereby reducing the contractility of smooth muscle and vascular resistance, so the drug can effectively prevent vasoconstriction and lower blood pressure.When entering the body, Amlibon has a direct mechanism of action that helps to relax the smooth muscle around the peripheral arteries but does not affect the atrioventricular conduction in the heart or the force of muscle contraction. In addition, Amlibon drug also reduces renal vascular resistance, thereby increasing blood flow and improving kidney function better.
2. Indications and contraindications to the use of Amlibon
What disease does Amlibon 10 treat? This drug belongs to the group of calcium channel blockers. Therefore, it is often used to treat hypertension, chronic stable angina as well as coronary spasm. If you have high blood pressure, Amlibon can dilate blood vessels so blood can flow more easily. If you have angina, Amlibon can increase the blood supply to the muscles, resulting in more oxygen and preventing angina. However, Amlibon does not immediately relieve angina.
However, Amlibon drug may also be contraindicated in some cases such as:
People with a history of allergy to the drug's components or allergy to calcium channel blockers; People with severely low blood pressure; Shock including cardiogenic shock; Left ventricular outflow tract obstruction such as severe aortic stenosis; Hemodynamically unstable heart failure following myocardial infarction within the previous 4 weeks.
3. Dosage and how to use Amlibon
The drug is used for both adults and children:
For adults, Amlibon is usually used with a starting dose of 5mg / day, equivalent to 1⁄2 Amlibon 10mg tablets. In case of necessity, the doctor can apply to increase the maximum dose to 10mg per day equivalent to 1 tablet of Amlibon 10mg but must depend on the response of the patient. In patients with hypertension, Amlibon is used concomitantly with thiazide diuretics, alpha-blockers, beta-blockers or angiotensin-converting enzyme inhibitors. In patients with angina, Amlibon may be used as monotherapy or in combination with other antianginal agents in patients with nitrate-resistant angina. No dose adjustment is required for concomitant use of Amlibon and thiazide diuretics, alpha blockers, beta blockers or angiotensin-converting enzyme inhibitors. For children under 18 years: Children 6 to 17 years old who have high blood pressure can use Amlibon with the starting dose, 2.5mg once a day. The dose can then be increased to 5mg per day. However, if your blood pressure does not reach the desired results after 4 weeks, you should see your doctor for advice. For children under 6 years of age, there are no data to recommend the use of Amlibon in children. In the elderly, the tolerability of the patient is similar to that of the younger population, so the drug can be used at the same dose as in adults. However, when increasing the dose for this subject should be carefully monitored. For people with kidney disease, the usual adult dose can be used. However, it is not possible to remove the drug component during dialysis. Special attention should be paid to those who need dialysis. For patients with hepatic impairment, there is currently no established setting for patients with mild to moderate disease. Therefore, when using the drug, the patient should follow the doctor's instructions and use a low starting dose. It should be noted: The above recommended therapeutic doses for Amlibon are for reference only. Therefore, before using Amlibon, patients need to be prescribed by a doctor.
In case the patient accidentally takes Amlibon drug in excess of the prescribed dose and has some signs of unwanted side effects, it is necessary to take the patient to the nearest emergency room.
4. Side effects and some notes when using Amlibon drug
Amlibon like any other medicine can cause unwanted side effects. However, not everyone who takes the drug experiences this condition. Possible side effects during treatment with Amlibon:
Blood and lymph can cause cases of leukopenia and thrombocytopenia. In rare cases, unexplained fever or sore throat and flu-like symptoms, decreased red blood cell count can cause bruising or nosebleeds. Metabolic disorder with hyperglycemia. Ankle swelling, flushing, hot flushes, changes in skin pigmentation. In case the patient has any unwanted side effects, they should stop using Amlibon and immediately contact the doctor for timely medical assistance.
Some Amlibon drug interactions:
When Amlibon is combined with anesthetics, it will increase the effect of the drug and lower blood pressure more strongly. Co-administration with non-steroid anti-inflammatory drugs, especially Indomethacin, can reduce the antihypertensive effect of Amlibon by inhibiting prostaglandin synthesis, keeping sodium and fluid in the body. Amlibon drug interacts with drugs that are highly protein bound, so a competitive reaction with the drug results in the concentration of the drug in the free form and may increase the drug concentration in the serum. Note the use of drugs for pregnant and lactating women:
Because calcium channel blockers can inhibit early uterine contractions but have no effect on the fertility process. Therefore, Amlibon should be used with special attention in the first 3 months of pregnancy. Above are the uses, doses and notes when using Amlibon medicine. To use Amlibon safely and effectively, patients need to use it exactly as prescribed by their doctor.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
