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Amlibon 5mg drug with the main ingredient is Amlodipine used to treat high blood pressure, angina pectoris. Amlodipine is well tolerated in patients with angina pectoris and is usually associated with only mild side effects, very rarely serious symptoms.
1. What is Amlibon 5mg?
Amlibon 5mg drug has the main ingredient Amlodipine in the form of amlodipine besilate which is an active ingredient of the Dihydropyridine group, which inhibits the flow of calcium ions through the smooth muscle membrane of the heart and blood vessels leading to vasodilation and smooth muscle. Therefore, the drug has the effect of lowering blood pressure and reducing angina pectoris, specifically as follows:
Amlodipine reduces blood pressure by the mechanism of reducing peripheral resistance (afterload pressure) on the vessel wall, helping blood circulate easily. than. Specifically, it dilates the peripheral arterioles. In addition, because Amlodipine does not affect the heart rate, it reduces the energy consumption and oxygen demand of the myocardium, thus reducing the burden of blood flow to the heart muscle. The mechanism of angina relief is that Amlodipine dilates the coronary arteries and coronary arterioles in the ischemic area, thereby increasing the oxygen supply to the myocardium, helping to relieve pain and reduce spasm. Amlibon 5mg drug is indicated in the following cases:
Essential hypertension; Chronic stable angina; Chest pain due to vasoconstriction.
2. Dosage of the drug Amlibon
Amlibon 5mg tablets are usually taken orally, do not chew or crush, break tablets, can be taken at any time because the drug is not hindered by food absorption. Do not take the drug with stimulants such as alcohol or beer. Reference dosage of the drug depends on the treatment goal, specifically as follows:
For adults:
Initial dose for patients with hypertension and angina pectoris: 5mg/time/day can be increased to 10mg /times/day depending on individual patient's response; Hypertension can be combined with other antihypertensive drugs such as thiazide diuretics, beta-blockers, ACE inhibitors without the need to adjust the dose of Amlodipine; Angina pectoris can be used alone or in combination with other angina relievers with Amlodipine in appropriate doses. For hypertensive children from 6-17 years old:
Initial antihypertensive dose: 2.5 mg/time/day; After 4 weeks, blood pressure readings have not reached the normal level, adjusted to 5mg / time / day. For special cases:
Elderly people take the same dose as adults if well tolerated, be cautious when increasing the dose; Amlodipine should not be used in patients with renal failure if hemodialysis is not possible; There are no studies on the dosing of Amlibon 5mg in patients with hepatic impairment.
3. Amlibon 5mg . side effects
Some unwanted effects when using Amlibon 5mg include:
Drowsiness, dizziness, headache; Palpitations; Abdominal pain, nausea; Edema, swelling of the ankle; Insomnia, depression; Tremor, arrhythmia, syncope; Visual disturbances, double vision; Tinnitus ; Shortness of breath, rhinitis; Muscle pain, joints, cramps; Nocturnal urination disorders; Rare: Hepatitis, pancreatitis, allergies, hyperglycemia, leukopenia, angioedema, erythema multiforme, Stevens-Johnson syndrome, photosensitivity. To avoid unwanted effects when using Amlibon 5mg, there are some contraindications that need to be followed as follows:
Patients with hypersensitivity to any ingredient in Amlibon 5mg; Patients with low blood pressure; Patients with cardiogenic shock; Hemodynamic instability after acute myocardial infarction; Severe aortic stenosis; Children under 6 years old.
4. Drug interactions with Amlibon 5mg
Some drug interactions affecting the use of Amlibon 5mg include:
CYP3A4 inhibitors such as the antifungal drugs Azole, antibiotics Macrolid and Aminoside all increase Amlodipine blood levels; Malignant hyperthermia drugs that increase serum potassium when used with antihypertensive drugs (Verapamil, Amlodipine) should be avoided; Co-administration of Amlodipine with grapefruit juice is not recommended because the antihypertensive effect may be increased in some patients; Co-administration of Amlibon 5mg with other antihypertensive agents increases the bioavailability of the combination drug; Amlodipine reduces plasma concentrations of the lipid-lowering drug Simvastatin, therefore the dose of Simvastatin should be doubled in patients receiving Amlodipine. Above are the uses, dosage and usage of Amlibon 5mg medicine. The article is for reference only, the use of the drug should be prescribed and guided by a doctor.
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