This is an automatically translated article.
Posted by Pharmacist Nguyen Le Trang - Faculty of Pharmacy, Vinmec Times City International General Hospital
Telmisartan inhibits the AT1 receptor of angiotensin II, reduces the effect of angiotensin II, thus has a vasodilator effect, and at the same time reduces aldosterone causing increased sodium excretion, thereby reducing blood pressure.
1. Indications and contraindications for drug use
Indications:
Treatment of essential hypertension, prevention of cardiovascular morbidity and mortality in patients 55 years of age and older at high risk of cardiovascular disease (coronary artery disease, peripheral arterial disease). , diabetes mellitus, history of stroke, transient ischemic attack).
Contraindications :
Hypersensitivity to the drug; biliary obstruction, severe liver failure
2. Caution
P women who are planning to become pregnant; renal artery stenosis , kidney failure , kidney transplant ; hypovolaemia, severe congestive heart failure, aortic stenosis; concomitant use of drugs that affect the renin-angiotensin-aldosterone system, primary hyperaldosteronism; hyperkalemia.
Cần thận trọng khi phối hợp với một số loại thuốc khác
3. Dosage form and content
Single ingredient form: Micardis tablets 40mg, 80mg.
Combination form: Twynsta (amlodipine/telmisartan) tablets 5 mg/40 mg, 5 mg/80 mg; Micardis Plus (telmisartan/hydrochloro thiazide) 40/12.5mg.
4. Dosage – how to use
Take orally.
Adults:
- Essential hypertension: Initial 40 mg/day, maintenance: 20 - 80 mg/day. Doses above 80 mg did not add to the clinical effect.
- Prevention of cardiovascular disease in people over 55 years old: 80 mg/day.
Children : Not enough information is available on safety and effectiveness when used in children under 18 years old
Phụ huynh cần cho trẻ uống thuốc theo đúng sự chỉ dẫn của bác sĩ
5. Unwanted effects and attention when using
Common : Dizziness, headache, hyperkalemia.
Uncommon: Hypotension after the first dose, erythema, diarrhea, gastrointestinal disturbances, liver dysfunction, myalgia, cramps, back pain, insomnia, decreased Hb, renal failure, pharyngitis, stuffy nose.
Rare: Cough, urticaria, angioedema, hepatitis, taste disturbance, migraine.
Should lie down or sit up slowly after taking the medicine to avoid dizziness. Check kidney function and electrolytes regularly during use
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