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Allerba 10 is prepared in the form of film-coated tablets, with the main ingredient being Ebastine. The drug is mainly used to treat symptoms of allergic rhinitis, idiopathic urticaria,...
1. Uses of the drug Allerba 10
Allerba 10 medicine has the main ingredient Ebastine 10mg. Ebastine is a derivative of piperidin - an antihistamine with no sedative effect.
Allerba 10 is indicated for use in the following cases:
Symptomatic treatment of seasonal and year-round allergic rhinitis, with or without allergic conjunctivitis; Improve symptoms of itching, reduce the formation of new bumps in people with idiopathic urticaria. Contraindications to the use of Allerba 10:
Hypersensitivity to Ebastine or other excipients of the drug; Not used to treat urticaria in adolescents under 18 years of age, there is no experience with the drug in children under 12 years of age; Women who are breastfeeding.
2. How to use and dose Allerba 10
2.1. How to use Film-coated tablets are to be swallowed whole with water, do not chew. Allerba can be taken with or without meals. The doctor will determine the appropriate time to take the drug for the patient.
2.2. Dosage Allergic Rhinitis: For adults and children over 12 years old, take 1 tablet (10mg) / time / day. In case of severe symptoms and year-round allergic rhinitis, a dose of 2 tablets/time/day can be used; Urticaria: For people over 18 years old, use 1 tablet/time/day; No dose adjustment is required in patients with renal failure treated for up to 5 days; No dose adjustment is required in patients with mild to moderate hepatic impairment treated for up to 7 days; In patients with severe hepatic impairment, do not exceed 10 mg/day. *Note: There are not many data on the use of Allerba in children under 12 years of age.
2.3. Overdose In studies with doses as high as 100 mg once daily, no clinically significant signs or symptoms of overdose were observed. In case of overdose, the patient should be monitored for vital functions (including an electrocardiogram with QT interval assessment) for at least 24 hours. The patient was treated symptomatically and gastric lavage was performed.
2.4. Missed dose If a dose of Allerba is missed, the patient should take it as soon as possible. If it is close to the next dose, the patient can skip the missed dose and take the next dose at the scheduled time.
3. Allerba 10 . side effects
When using Allerba 10, patients may experience some side effects such as:
Common: Sleepiness, headache, dry mouth; Uncommon: Nosebleeds, rhinitis, pharyngitis, nausea, abdominal pain, dyspepsia, insomnia, asthenia, dizziness; Very rare: Tachycardia, palpitations, tactile disturbances, sinusitis, vomiting, rash, urticaria, rash, eczema, dermatitis, edema, abnormal liver function tests, dysmenorrhea , menstrual disorders, unclear agitation,... When experiencing side effects of Allerba 10, patients should stop taking the drug and immediately notify their doctor or go to the nearest medical facility for advice. timely handling.
4. Be careful when using Allerba
When using Allerba 10, patients should note:
Caution when using Ebastin (the main ingredient of Allerba drug) in patients with prolonged QT interval on electrocardiogram, hypokalemia and other cases concomitant use with drugs that increase the QT interval or inhibit the liver enzyme system CYP450 -2J2, -4F12 or 3A4 (such as azole antifungals and macrolide antibiotics); Allerba should be used with caution in patients with severe hepatic impairment; Allerba should be used in pregnant women only when clearly needed (with doctor's approval); Allerba should not be used in women while breastfeeding;
5. Allerba drug interactions
Some drug interactions of Allerba 10 include:
Interaction between Ebastine and ketoconazole or erythromycin (a drug that prolongs the QT interval) causes a higher plasma concentration of Ebastine, the QT interval prolongs about 10 milliseconds compared to when administered. ketoconazole or erythromycin alone; There is no interaction between Ebastine and warfarin, theophylline, cimetidine, diazepam or alcohol; Plasma concentrations of carebastine (the main active metabolite of Ebastine) are 1.5-2-fold increased and AUC is increased while Tmax remains constant when the drug is administered with food. However, the clinical effect was not affected. When taking Allerba 10, patients should strictly follow the doctor's instructions. Patients should inform their doctor about their medical history, allergies, and medications they are taking for appropriate advice.
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