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Alclav 1000mg is a broad-spectrum antibiotic, used to treat severe respiratory infections, severe urinary tract infections, skin and soft tissue infections or dental infections... To ensure effectiveness when using Aldezil , users need to follow the instructions of their doctor and refer to the following article for more information about the use of Aldezil.
1. What are the effects of Alclav 1000mg?
1.1. What is Alclav 1000mg? Alclav 1000mg drug has the main ingredient Amoxicillin trihydrate, equivalent to Amoxicillin 875mg. Clavulanate potassium equivalent to Clavulanic acid 25mg and excipients: Croscarmellose sodium; colloidal silicon dioxide; talc; magnesium stearate; hydroxypropyl methyl cellulose E-5; ethyl cellulose; diethyl phthalate; titanium dioxide; hydroxypropyl methyl cellulose E-15; polyethylene glycol 6000.
Alclav 1000mg is a product manufactured by Alkem Laboratories Ltd. Has registration number VN-17632-14. Aldezil is prepared in the form of tablets, packaged in a box of 1 blister, each blister of 10 tablets. Amoxicillin is a semi-synthetic beta-lactam antibiotic with a broad bactericidal spectrum against many Gram-positive and Gram-negative bacteria by inhibiting bacterial cell wall synthesis. But amoxicillin is very easily degraded by lactamase enzymes due to hydrolysis of the B-lactam ring, so it is not effective against these yeast-producing strains.
1.2. What diseases does alclav 1000mg treat? Amoxicillin and clavulanic acid preparations are used for the short-term treatment of infections caused by susceptible organisms. Alclav 1000mg is indicated for use in the following cases:
Severe upper respiratory tract infections: Tonsillitis, sinusitis and otitis media have been treated with common antibiotics but have not improved. Infections of the lower respiratory tract by beta-lactamase-producing strains of H.influenzae and Branhamella catarrbaiis: Such as acute and chronic bronchitis, bronchopneumonia. Severe infections of the urogenital tract by beta-lactamase-producing strains of E.coli, Klebsiella and Enierobacter: Cystitis, urethritis and pyelonephritis (female genital tract infection). Skin and soft tissue infections: Boils, abscesses and wound infections. Bone and joint infections: Osteomyelitis. Dental infection: Alveolar abscess. Other infections: Infections caused by abortion, obstetric bacteremia, intra-abdominal infections (intra-abdominal infections in bacteremia, peritonitis, postoperative infections, prevention of infections during gastro-intestinal surgery). , uterus, head and neck, heart, kidney, joint replacement, and biliary tract). Contraindications:
Alclav 1000mg is not recommended for:
People who are sensitive to any of the ingredients of Alclav 1000mg. The patient has a history of an allergic reaction to any penicillin. Patients with a history of liver dysfunction, jaundice caused by Amoxicillin or Clavulanate Potassium.
2. Usage of Alclav 1000mg
2.1. How to take Alclav medicine Alclav 1000mg tablet is taken orally. Patients should take the drug with meals to reduce side effects on the stomach and intestines.
2.2. Dosage of the drug Alclav 1000mg Alclav 1000mg tablets are only used under the prescription of a doctor. The drug has different recommended doses for each indication:
Adults: Take 1 tablet of Alclav 1000mg/day. For severe infections and respiratory tract infections: Take 1 tablet of Alclav 1000mg every 12 hours. Children: Children from 40kg or more, take Alclav 1000mg according to the adult dose. Patients with renal impairment: No dose reduction is required unless renal impairment is severe. Patients with severe renal failure with glomerular filtration rate less than 30ml per minute and children weighing less than 40kg: Alclav 1000mg film-coated tablets should not be used. Note: Treatment should not exceed 14 days without re-examination.
Handling missed dose:
You should take the forgotten dose of Alclav 1000mg as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue taking it at the prescribed time. Do not take 2 doses at the same time. Do not change the dose or stop the drug. Treatment of overdose:
The majority of patients are asymptomatic after overdose or have mainly gastrointestinal symptoms including abdominal pain, stomach pain, vomiting, diarrhea, rash, increased active or sleepy. In case of overdose, amoxicillin + clavulanic acid should be discontinued, symptomatic treatment and supportive measures instituted if necessary. If an overdose is recent and there are no contraindications, attempts should be made to induce vomiting or possibly other means to remove the drug from the stomach. Interstitial nephritis leading to renal failure and oliguria have been reported in a small number of patients following amoxicillin overdose. Renal failure is reversible upon discontinuation of the drug. High blood levels may be more likely in patients with impaired renal function due to decreased renal clearance of amoxicillin and clavulanate potassium. Both amoxicillin and clavulanic acid are removed from the circulation by dialysis.
3. Note when using Alclav 1000mg
Serious and sometimes fatal hypersensitivity reactions (anaphylaxis) have been reported in patients receiving beta-lactam antibiotics. If an allergic reaction occurs, the patient should discontinue Amoxicillin and institute appropriate alternative therapy. Amoxicillin should be avoided if infectious mononucleosis is suspected. Prothrombin time prolongation, although rare, has been reported in patients receiving amoxicillin. Close monitoring is recommended when co-administered with anticoagulants. When taking high doses of Alclav 1000mg, it is necessary to maintain adequate water intake and excretion through urine. Dose adjustment is recommended for patients with renal impairment (see full prescribing information). Amoxicillin may decrease the effectiveness of oral contraceptives. Pregnant and nursing women should consult their doctor before taking Alclav 1000mg.
4. Side effects of Alclav 1000mg
When using Alclav 1000mg, patients may experience unwanted effects (ADRs).
Gastrointestinal side effects, such as nausea, vomiting and diarrhea, appear to be more common with amoxicillin/clavulanic acid than with amoxicillin alone. Adverse events reported in patients receiving amoxicillin/clavulanic acid were approximately 13%, requiring discontinuation in less than 3% of patients. Initial side effects are mild gastrointestinal upset or irritation including diarrhea, nausea, vomiting, and indigestion. There have been isolated reports of urticaria, anaphylaxis, behavioral changes, and laboratory abnormalities. Gastrointestinal side effects can be reduced if the drug is taken with meals. If you experience these symptoms, the patient should stop using Alclav 1000mg and notify the doctor for appropriate treatment.
5. Drug interactions Alclav 1000mg
Probenecid reduces the renal tubular secretion of amoxycillin. Concomitant use of this drug with amoxycillin may increase and prolong blood levels of amoxycillin. Absorption of amoxicillin is not affected by food in the stomach, so it can be taken before or after meals. Nifedipine increases the absorption of amoxicillin. When allopurinol is taken with amoxicillin, there is an increased chance of amoxicillin rash. There may be antagonism between the biocide amoxicillin and bacteriostatic agents such as chloramphenicol and tetracycline. In addition, when using Alclav 1000mg with foods or alcohol, beer, tobacco... because those foods and drinks contain other active ingredients, it may affect the phenomenon of antagonism or antagonism. synergistic with drugs. Patients should carefully read the instructions for use of the drug or consult a doctor or pharmacist about taking Alclav 1000mg tablets with food, alcohol and tobacco.
6. How to store Alclav 1000mg
The shelf life of Alclav 1000mg drug is 36 months from the date of manufacture. Store Alclav 1000mg in a cool, dry place, at a temperature not exceeding 30°C, in the original packaging and protected from light. Keep Alclav 1000mg out of reach of children and pets. Above is all information about Alclav 1000mg drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Alclav 1000mg treatment at home because there may be unwanted side effects.
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