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Acezin 5mg medicine has the main ingredient is Alimemazine tartrate, which works to treat allergy symptoms. Acezin dhg 5mg is manufactured and registered by DHG Pharmaceutical Company Limited - VIETNAM.
1. What is Acezin 5mg?
Acezin 5mg is a prescription drug, belonging to the group of anti-allergic drugs and used for cases of hypersensitivity. Acezin dhg 5mg medicine has the main active ingredient is Alimemazine tartrate.
Dosage form: film-coated tablets, pink tablets. Each tablet contains 5mg Alimemazine tartrate and excipients just enough.
Packing form: box of 2 blisters, each blister contains 25 tablets. Pharmacodynamics: Alimemazine is a derivative of phenothiazines, with strong anti-histamine and serotonin effects. Alimemazine competes with histamine at the H1 receptor, thereby antagonizing the pharmacological effects of histamine (such as urticaria, itching, ...). On the other hand, alimemazine inhibits the enzyme histamine N - methyltransferase and blocks central histamine and serotoninergic receptors, so alimemazine has a sedative effect. In addition, alimemazine exerts an antiemetic effect through direct action on chemosensitive areas of the spinal cord, possibly by blocking dopaminergic receptors in this region.
Pharmacokinetics: After taking the drug 15-20 minutes, Alimemazine is rapidly absorbed from the gastrointestinal tract and has a lasting effect of 6-8 hours. The drug is in the form of binding to plasma proteins (20-30%). The mean half-life is 3.5 - 4 hours. Alimemazine is eliminated by the kidneys as sulfoxide metabolites.
2. Effects of the drug Acezin dhg 5mg
Acezin dhg 5 drug is indicated in the following cases:
Respiratory allergies (with manifestations of rhinitis, sneezing, runny nose) and skin allergies (rash, urticaria, itchy papules). Dry cough (due to allergies or irritation, especially in the afternoon and at night) Insomnia Frequent vomiting in children. Contraindications: absolutely do not use Acezin dhg 5mg in the following cases:
Hypersensitivity to drug components or phenothiazine derivatives. People with liver and kidney dysfunction, epilepsy, Parkinson's disease, myasthenia gravis, pheochromocytoma, thyroid dysfunction, angle-closure glaucoma, prostatic hypertrophy. Cases of overdose due to opiates, barbiturics, alcohol. History of agranulocytosis Special subjects: children under 6 years old, pregnant women, lactating women.
3. Dosage and how to use Acezin dhg 5
Acezin dhg 5 is a prescription drug, so you must absolutely follow your doctor's instructions, do not arbitrarily increase or decrease, change the route of medication, or give this medicine to others when they have it. the same symptoms as you.
Treatment of insomnia:
Adults: take 5 - 20mg before going to bed. Children over 2 years old: 0.25 - 0.5mg/kg/day, taken at night before going to bed Treatment of urticaria and itchy papules:
Adults: 2 tablets/time x 2-3 times/day. May be up to 100mg/day if persistent, difficult to cure. Children over 2 years old: 0.5 - 1 tablet divided 3-4 times/day Elderly: 2 tablets/time x 1-2 times/day Anti-histamine, anti-cough treatment:
Adults: 1-2 tablets /time x 3 - 4 times/day Children over 2 years old: 0.5 - 1 tablet, divided 3 - 4 times/day Treatment of alcoholic agitation: 50-200mg/day.
What to do in case of missed dose or overdose?
In case of missed dose: it is important to always take the correct dose as directed by your doctor. However, if you miss a dose, take the next dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next dose. In case of overdose: some symptoms may be encountered when overdosing such as: somnolence, loss of consciousness, hypotension, increased heart rate, arrhythmia, hypothermia, extrapyramidal reactions. An emergency center should be contacted immediately for treatment. Currently, there is no specific antidote for Acezin dhg 5mg, it is possible to rinse the stomach, use activated charcoal. If in case of cardiovascular collapse, arrhythmia, central nervous system depression should be treated supportively.
4. Undesirable effects of Acezin 5mg
During the treatment with Acezin dhg 5mg, you may experience unwanted effects such as:
Fatigue, headache, dizziness, drowsiness, dry mouth, constipation, urinary retention, ...
Rare: leukopenia, agranulocytosis, decreased blood pressure, increased heart rate, Parkinson's tremor, restlessness, dystonia....
Tell your doctor about any symptoms you experience must be consulted.
Besides, note, do not drink alcohol while taking Acezin dhg 5 because alcohol increases the sedative effect of the drug. When co-administered with barbituric hypnotics and other sedatives, the central nervous system and respiratory depression of acezin dhg 5mg is increased. Other anticholinergics potentiate the anticholinergic effects of acezin.
5. Some notes when using Acezin 5mg
Do not use when driving and operating machinery because of the risk of drowsiness of the drug.
Caution when used for the elderly and cardiovascular patients.
Hopefully, with the sharing of Acezin 5mg medicine, it will help you better understand how to use it as well as what to do in case of missed dose or side effects for the best effect.
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