Uses of Acetyl Max

This is an automatically translated article.

Acetyl Max is prepared as a powder for oral suspension with the main ingredient being 200mg Acetylcysteine. So what is Acetyl Max used for and how is it used? Please read the following article.

1. What are the uses of Acetyl Max?


Acetylcysteine ​​(N - acetylcysteine) in the drug Acetyl max is the N - acetyl derivative of L - cysteine, this is a natural amino - acid. Acetylcysteine ​​has a mucolytic effect and is also an antidote to Paracetamol overdose.
Acetylcysteine ​​reduces the viscosity of lung mucus with or without pus, by cleaving the disulfide bridge in the mucoprotein molecule. Thereby facilitating the expulsion of mucus through the cough reflex, postural drainage or by other mechanical means.
After oral administration, Acetylcysteine ​​will be rapidly absorbed in the gastrointestinal tract and deacetylated by the liver to cysteine, then metabolized. Peak plasma concentrations are reached approximately 0.5 to 1 hour after a dose of 200 to 600 mg. The oral bioavailability of the drug is low and may be due to metabolism in the intestinal wall and first-pass metabolism in the liver. Renal clearance may account for 30% of systemic clearance.
Acetyl Max is indicated in the following cases:
Mucus removal in mucoviscidosis (cystic fibrosis of the pancreas). Respiratory pathology with viscous sputum as in acute and chronic bronchitis. Routine cleaning in tracheostomy. Acetyl Max is contraindicated in the following cases:
Children under 2 years old. People with a history of asthma are at increased risk of a bronchospasm reaction to all forms of acetylcysteine. Hypersensitivity to Acetylcysteine. Caution when using Acetyl Max:
Must closely monitor patients at risk of asthma, if using Acetylcysteine ​​for people with a history of allergies. If the patient has bronchospasm, a bronchodilator nebulizer such as Salbutamol (a short-acting, selective beta-2 adrenergic agent) or Ipratropium (an anti-muscarin) must be used and Acetyl Max should be discontinued immediately. . During treatment with Acetyl max, there may be a lot of thin sputum in the bronchi, which needs to be aspirated to remove sputum if the patient's ability to cough is reduced. Treatment of paracetamol overdose with Acetyl Max in pregnant women is effective and safe, and has the ability to prevent liver toxicity of the fetus as well as of the mother. Acetyl Max is safe for use by women who are breastfeeding.

2. Dosage and how to use Acetyl Max


Acetyl Max is used orally. Mix the pack with cooled boiled water. Dosage of the drug should be according to the doctor's prescription, the reference dose is as follows:
Adults and children over 6 years old: Use a dose of 1 pack/time x 3 times/day. Children from 2 to 6 years old: Use 1 sachet/time x 2 times/day. An overdose of Acetyl Max will have symptoms similar to those of anaphylaxis, but much more severe, especially a drop in blood pressure. Other symptoms of Acetyl Max overdose include respiratory depression, hemolysis, disseminated intravascular coagulation, and renal failure.
Death has occurred in a patient with an overdose of Acetylcysteine ​​while being treated for Paracetamol poisoning. Acetylcysteine ​​overdose occurs when the drug is administered too quickly and at too high a dose. Treatment of overdose with Acetyl max is symptomatic.

3. Acetyl Max drug side effects


Acetyl Max has a wide safety margin. Although clinically apparent bronchospasm due to Acetylstein is rare, it can occur with all forms of Acetylcysteine.
Common side effects of Acetyl Max include:
Nausea, vomiting. Less common side effects of Acetyl Max include:
Drowsiness; Headache; Tinnitus ; Stomatitis; A lot of runny nose; Rash; You are jute. Rare side effects of Acetyl Max include:
Bronchospasm accompanied by a systemic anaphylactic reaction. Fever . So cold. If you experience any side effects of Acetyl max, you should immediately notify your doctor or go to a medical facility for timely support from medical staff.
How to handle side effects of Acetyl Max:
Using diluted Acetylcysteine ​​solution can help reduce the possibility of causing vomiting due to the drug. Need to treat anaphylaxis immediately with subcutaneous injection of Adrenalin (0.3 - 0.5 ml of 1/1000 solution), 100% oxygen ventilation, if necessary, intubation, intravenous fluids to increase plasma volume, inhale beta-adrenergic agonist if bronchospasm is present, intravenous hydrocortisone 500mg or methylprednisolone 125mg. Acetylcysteine ​​hypersensitivity reactions including generalized rash, pruritus, dizziness, nausea, vomiting can be inhibited by pre-administration of an antihistamine.

4. Acetyl Max interactions with other drugs


Acetylcysteine ​​is a reducing agent, so it is not suitable for use with oxidizing agents. Acetyl Max should not be used concurrently with other cough medicines or any drugs that reduce bronchial secretions during treatment with Acetyl Max. The article has provided information about the uses, dosage and precautions when using Acetyl Max. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Acetyl max exactly as directed by your doctor.

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.

Share
Patients Stories