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The main ingredient Acethepharm has is Acetylcysteine, an active ingredient that has the effect of breaking down mucus and is used to treat mucoviscidosis and other respiratory diseases. Here is some information to help you understand what Acethepharm does? How to use?1. What are the effects of Acethepharm?
Acethepharm drug has the main ingredient Acetylcysteine (N_acetyl derivative of L-cysteine, a natural amino acid). The drug is effective in reducing mucus in mucoviscidosis (viscous mucus disease or cystic fibrosis of the pancreas), treating respiratory diseases with thick mucus in acute and chronic bronchitis, routine cleaning during tracheostomy.
After oral administration, the drug is rapidly absorbed from the gastrointestinal tract and is deacetylated by the liver to cysteine, peak plasma concentration in about 0.5-1 hour after oral dose of 200-600mg.
2. Dosage and how to use Acethepharm
Acethepharm needs to be mixed with water before drinking. Dosage is divided as follows:
Dosage for adults and children over 6 years old is 2 packs/time, 3 times/day; Dosage for children from 2-6 years old is 2 sachets/time, 2 times/day.
3. Contraindications to using Acethepharm
Acethepharm is contraindicated in the following cases:
Having a history of asthma increases the risk of bronchospasm reactions to all forms of Acetylcysteine; Hypersensitivity to Acetylcysteine and other components of the drug; Contraindicated in children under 2 years of age.
4. Be careful when using Acethepharm
During the use of Acethepharm, the following should be noted:
Closely monitor people with a history of asthma and allergies, in case of bronchospasm, stop the drug, change to bronchodilator nebulizer Salbutamol or Ipratropium. For people with a reduced ability to cough, it is necessary to use a sputum suction procedure. In pregnant women, treatment of paracetamol overdose with Acethepharm is safe and effective. has the ability to prevent toxicity to the liver of the fetus and mother. Acethepharm is safe for breastfeeding women.
5. Acethepharm side effects
Acethepharm has a wide safety margin, although clinically apparent bronchospasm is rare, it can still occur with all forms of Acetylcysteine. Side effects include:
Common: Nausea, vomiting. Uncommon: Drowsiness, headache, tinnitus; stomatitis, runny nose; rash, urticaria. Rare: Poor bronchospasm with systemic anaphylaxis; fever, chills.
6. Instructions on how to handle side effects
Reduce the risk of vomiting by using diluted Acetylcysteine solution. In case of anaphylaxis, immediate subcutaneous injection of adrenaline 0.3-0.5ml of 1/1000 solution, 100% oxygen ventilation, endotracheal intubation if necessary, intravenous fluids to increase plasma volume, inhaled agonist beta - adrenergic if bronchospasm, intravenous 500 mg hydrocortisone or 125 mg methylprednisolone . Hypersensitivity reactions to Acetylcysteine, including generalized erythema, pruritus, nausea, vomiting, and dizziness, may be suppressed by pre-administration of antihistamines. Up to 3% of people who received acetylcysteine intravenously to treat an overdose of Paracetamol experience hypersensitivity reactions, combined with many suggesting that hypersensitivity is due to a pseudoallergic mechanism based on histamine release rather than an immunological cause. epidemic, so doctors should pay attention to use antihistamines to prevent.
7. Drug interactions
Some drug interactions that may occur when taking Acethepharm include:
Acetylcysteine of the drug is a reducing agent, so it is not suitable for oxidizing agents. Do not use concurrently with other cough medicines or drugs that reduce bronchial secretion. The article has provided information on what Acethepharm is used for, dosage and precautions for use. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Acethepharm exactly as directed by your doctor. Store Besfluran in a cool dry place and out of the reach of children.
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