This is an automatically translated article.
Acetylcysteine is a mucolytic, mucolytic agent that acts on the gel phase of the mucus by severing the disulfur bonds of glycoproteins. This is also the main active ingredient in Phabalysin 200.
1. What is Phabalysin 200?
Phabalysin 200 is a drug that belongs to the group of drugs that act on the respiratory tract. Phabalysin 200 has the ingredient Acetylcysteine 200mg, which is prepared in the form of a powder pack of 2g. Phabalysin drug is manufactured by Central Pharmaceutical Company 1, the drug is circulated in Vietnam with registration number VD-29858-18.
2. What are the uses of Phabalysin 200?
Acetylcysteine is the N - acetyl derivative of L - cysteine, this is a natural amino - acid used as a mucolytic agent and an antidote to Paracetamol overdose. Phabalysin 200 reduces the viscosity of sputum in the lungs (purulent or not) by splitting the disulfide bridge in the mucoprotein structure, thereby creating favorable conditions for expelling sputum out by coughing, postural drainage. or use mechanical methods.
Acetylcysteine in Phabalysin 200 is used to protect against hepatotoxicity caused by paracetamol overdose by maintaining or restoring hepatic glutathione levels. Glutathion is essential for inactivation of the hepatotoxic intermediate metabolite of Paracetamol. In the event of an overdose of Paracetamol, a large amount of Paracetamol's metabolite (hepatotoxic) is metabolized by the major route of metabolism (glucuronide and sulfate conjugation) becoming saturated. Acetylcysteine will be converted to cysteine, which stimulates the liver to synthesize glutathione and therefore, Acetylcysteine may protect the liver if the patient starts treatment within 12 hours of Paracetamol overdose, remember to start detoxification treatment as soon as possible. the better.
Indications of Phabalysin 200 are mucolytic in acute and chronic bronchopulmonary diseases accompanied by increased mucus secretion.
The drug is not allowed to be prescribed to patients with hypersensitivity to Acetylcysteine or one of the other ingredients of the drug.
3. Dosage and how to use Phabalysin 200
Phabalysin 200 is used orally, carefully read the instructions on how to use Phabalysin 200 written on the instruction sheet, do not arbitrarily use other routes not listed on the instruction sheet.
Dosage of Phabalysin 200 for mucolytic:
Adults and children > 14 years old: 1 packet of Phabalysin 200 / time, 2-3 times / day; Children 6-14 years old: 1 pack of Phabalysin 200/time, 2 times/day or half a pack of Phabalysin 200/time, 3 times/day; Children 2 - 5 years old: half a packet of Phabalysin 200/time, 2-3 times/day. Dosage of Phabalysin 200 to increase mucus secretion:
Children > 6 years old: 1 pack of Phabalysin 200/time, 3 times/day. Children 2 - 5 years old: half a packet of Phabalysin 200/time, 4 times/day. The differences in the dose of children's drugs compared to adults such as pharmacokinetics, pharmacodynamics, side effects... especially this is a subject that is not allowed to be tested, so it is necessary to use the drug for children who need it. Be very careful, even with drugs that have not been warned of danger to children.
In case you miss a dose of Phabalysin 200 while taking it, take it as soon as possible (usually you can take Phabalysin 200 1-2 hours apart from the indicated). However, if it is almost time for your next dose, skip the missed dose of Phabalysin 200 and take your next dose at the prescribed time, do not take a double dose of Phabalysin 200.
4. Note when using Phabalysin 200
Pregnant and lactating women, children < 2 years old should not use Phabalysin 200.
Phabalysin 200 used during pregnancy can cause bad effects (miscarriage, teratogenicity, fetal malformation ...), especially in the first 3 months. Therefore, it is best not to use Phabalysin 200 for pregnant women. In case it is necessary to use Phabalysin 200, it is necessary to consult carefully with your doctor, pharmacist. Phabalysin 200 medicine can be passed to the baby through breastfeeding, it is best not to or limit the use of Phabalysin 200 during breastfeeding. Many drugs have not yet identified all the effects during this period, mothers need to carefully read the instructions for use and consult with doctors and pharmacists.
5. Side effects of Phabalysin 200
Digestive disorders ; Stomatitis; Tinnitus . It should be noted that this is not a complete list of the side effects of Phabalysin 200. During use, other side effects may occur that are not specified in the instructions for use, now consult with us. doctor or pharmacist.
6. Drug interactions of Phabalysin 200
When using 2 or more drugs at the same time, it is easy to interact with drugs leading to antagonism or synergism. Drug Phabalysin 200 may interact with:
Nitroglycerin; Tetracyclines; Cough medicine. When using Phabalysin 200 with foods or alcohol, beer, tobacco... can affect the phenomenon of antagonism or synergism with the drug. Carefully read the instructions for use of Phabalysin 200 or consult your doctor or pharmacist about taking Phabalysin 200 with food, alcohol and tobacco.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
