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Aceclofenac is a non-steroidal anti-inflammatory agent, present in the product Acepental. So what does Acepental do and how is it indicated?
1. What is Acepental?
Acepental has the main active ingredient Aceclofenac 100mg. Acepental is manufactured by Phil Inter Pharma Co., Ltd (Vietnam) and is registered for circulation with the registration number VD-32439-19.Acepental is prepared in the form of soft capsules for oral use, packed in 1 blister or 10 blisters in each box, respectively, each blister contains 10 tablets.
2. What are the effects of Acepental?
The active ingredient Aceclofenac in Acepental is a non-steroidal anti-inflammatory drug (NSAID), so it has an effective analgesic and anti-inflammatory effect in cases of chronic osteoarthritis, rheumatoid arthritis or ankylosing spondylitis. match .Acepental is well absorbed from the gastrointestinal tract, however, taking with food can make Aceclofenac more slowly absorbed. After absorption, Acepental is strongly bound to plasma proteins and due to its first-pass metabolism, oral bioavailability is only about 50%. Acepental is eliminated mainly in the urine.
3. Indications and contraindications of Acepental
Acepental is indicated for the purpose of pain relief, anti-inflammatory in the following cases:
Chronic osteoarthritis; Rheumatoid arthritis; Ankylosing spondylitis. However, because it belongs to the NSAID class, Acepental is contraindicated in patients with the following problems:
Patients with active peptic ulcer disease or a history of suspected gastric ulcer or gastrointestinal bleeding chemical ; Patients with moderate to severe renal impairment; Relative contraindications for patients with severe hepatic impairment, requiring close monitoring of the patient during treatment with Acepental; Acepental should only be administered to pregnant women in cases of absolute need and should be used at the lowest effective dose; Acepental is contraindicated in patients with a history of allergy or hypersensitivity to Aceclofenac or a history of bronchial asthma, rhinitis, or acute rash following use of aspirin or other NSAIDs. Patients need to follow the instructions for using Acepental as recommended by the manufacturer or as directed by the treating doctor.
4. Dosage of the drug Acepental
The recommended dosage of Acepental is as follows:
Adults: 1 Acepental tablet (equivalent to 100mg Aceclofenac) x 2 times a day; Children: Acepental should not be used because there are no clinical data on the use of Aceclofenac; Elderly: The pharmacokinetics of Aceclofenac are unchanged in elderly patients, so no dose or frequency adjustment of Acepental is necessary for this population. Patients need to use the exact recommended dose of Acepental in the drug leaflet or prescribed by the doctor. Absolutely do not arbitrarily change the dose or frequency of use during the day than prescribed.
5. Acepental side effects
The majority of Acepental side effects are reversible and are mostly mild, including gastrointestinal disturbances (such as dyspepsia, epigastric pain, nausea and diarrhea) and some The patient may experience dizziness.
Some other side effects of Acepental include:
Rash, itchy skin and urticaria; Increased liver enzyme levels; Increased serum creatinine.
6. Be careful when using Acepental
Attention to possible adverse interactions when using Acepental concurrently with the following drugs:
Lithium; Digoxin; Oral medications for diabetes; Anticoagulants ; Diuretic; Other pain relievers. Acepental should be used with caution in the following subjects:
Patients with gastrointestinal dysfunction or a history of peptic ulcer; Patients with severe hepatic impairment, heart failure or renal insufficiency; Persons being treated with diuretics; Patients in the recovery period after surgery; Elderly; Alcoholics. Avoid the use of Acepental in pregnant or lactating patients. This subject only uses the drug when prescribed by the doctor and should use the lowest effective dose. Acepental medicine has the main active ingredient Aceclofenac, which is an anti-inflammatory pain reliever that should be used to treat osteoarthritis diseases effectively. To ensure effective treatment and avoid unwanted side effects, patients need to take the drug exactly as directed by the doctor or pharmacist.
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