Treatment of autoimmune diabetes LADA

This is an automatically translated article.


Latent autoimmune diabetes in adults (LADA) is also known as type 1.5 diabetes. Like type 1 diabetes, LADA forms when the immune system creates antibodies to attack the insulin-producing cells of the pancreas. Is autoimmune diabetes curable?

1. What is LADA Autoimmune Diabetes?


Latent Autoimmune Diabetes in Adults (LADA) slow progression, sometimes also called type 1.5 diabetes. Like type 1 diabetes, LADA occurs when the pancreas stops producing enough insulin. The cause may be due to certain toxic substances that damage the insulin-producing cells in the pancreas. However, the difference from type 1 diabetes is that people with LADA do not need insulin treatment for a long time after being diagnosed with the disease.
Many researchers believe that LADA autoimmune diabetes is a subtype of type 1 diabetes, while others do not recognize it as a separate form. It is hypothesized that diabetes occurs on a continuum, and that LADA is somewhere between type 1 and type 2 diabetes.
First, LADA can be treated by controlling blood sugar through diet. , keep a healthy weight, exercise, and possibly take certain medications. But as the body gradually loses its ability to produce insulin, the patient will eventually need insulin injections.

Có thể điều trị LADA bằng thuốc trong khoảng thời gian đầu
Có thể điều trị LADA bằng thuốc trong khoảng thời gian đầu

More research is needed to establish the best treatment for LADA autoimmune diabetes. Overall, like other types of diabetes, patients will need close monitoring to minimize diabetes progression and potential complications.

2. Diagnosis of LADA . Autoimmune Diabetes


People with LADA autoimmune diabetes are often over the age of 30 - older than the age when type 1 diabetes symptoms start to develop. Because the patient's pancreas still produces some insulin initially, LADA autoimmune diabetes often misdiagnosed with type 2 diabetes.
The only way to definitively diagnose LADA autoimmune diabetes is through a blood test. Your doctor will check for antibodies against the insulin-producing cells of the pancreas, as well as the level of the protein C-peptide the body makes.
If you have been diagnosed with type 2 diabetes, but your symptoms do not seem to be improving despite taking medication, or you have recently experienced unexplained weight loss, talk to your doctor about your risk. with LADA autoimmune diabetes as well as tailoring treatment to the most appropriate.
Some experts suggest that insulin treatment at diagnosis can help maintain beta cell function. Therefore, early and accurate diagnosis plays a very important role.

Cách duy nhất để chẩn đoán đái tháo đường là xét nghiệm máu
Cách duy nhất để chẩn đoán đái tháo đường là xét nghiệm máu

3. Treatment of autoimmune diabetes LADA


Is autoimmune diabetes curable? Like other types of diabetes, the goals of treatment for LADA autoimmune diabetes are good blood glucose control and prevention of complications. Due to the gradual destruction of beta cells over time, patients need to choose an option to maintain cellular function.
Type 1.5 diabetes occurs when the body does not produce enough insulin, but because it progresses slowly at first, oral medications for type 2 diabetes are effective. If the patient is also overweight or obese, a weight loss regimen with diet and increased exercise is required.
When beta cell function declines, oral hypoglycemic drugs lose the ability to maintain blood glucose after eating and fasting, patients will be at high risk of oxidative stress - an important mechanism of complications. diabetes. People with type 1.5 diabetes may also test positive for at least one of the type 1 diabetes antibodies.
When the body stops producing enough insulin, the patient will need insulin supplements. for the treatment of LADA autoimmune diabetes. Typically, patients will need insulin treatment about 5 years after diagnosis, but insulin should be started early to limit chronic complications. Studies show that insulin treatment as early as 1 year after diagnosis slows beta cell destruction. Furthermore, patients will also have better control of their metabolism, insulin secretion, and autoimmune responses against beta cells.

Overall, insulin is the first-line treatment for autoimmune type 1.5 diabetes. There are many different types of insulin and treatment regimens, and the dose of insulin needed will also vary from day to day. Therefore, people with LADA autoimmune diabetes need to monitor their glucose levels through regular blood glucose testing.

Theo dõi nồng độ glucose trong máu thường xuyên để có phương án điều trị bệnh phù hợp
Theo dõi nồng độ glucose trong máu thường xuyên để có phương án điều trị bệnh phù hợp

4. Complications and prognosis of autoimmune diabetes LADA


Life expectancy for people with LADA autoimmune diabetes is similar to that of other diabetic patients. In the past, people with type 1 diabetes often had a short life expectancy. However, treatments for diabetes have improved significantly. With tight disease control, patients can completely achieve a normal life expectancy.
High blood sugar for a long time leads to complications, such as kidney disease, heart problems, eye and nerve problems. Thyroid disease is also more common in people with LADA autoimmune diabetes than type 2 diabetes. Their wound healing is also slower and they are more likely to get infections. With good blood glucose control, many of these complications can be prevented.
Currently, there is no way to prevent LADA autoimmune diabetes. Like type 1 diabetes, genetic factors may play a role. Early and accurate diagnosis, combined with close management of symptoms, is the best way to avoid dangerous complications.
In summary, the symptoms of LADA autoimmune diabetes will progress slowly, patients will not need treatment for autoimmune diabetes for months or years after diagnosis. Initially, people with LADA can take type 2 diabetes medications, combined with dietary and lifestyle changes. Then, as the body gradually damages the insulin-producing cells of the pancreas, the person will need insulin to control blood sugar.
To register for examination and treatment at Vinmec International General Hospital, you can contact Vinmec Health System nationwide, or register online HERE.
Reference source: webmd.com; mayoclinic.org
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