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Pregnant women at risk of preterm birth or threatened with premature birth are often prescribed lung maturation injections by doctors. So what is the effect of lung maturation medicine on the fetus and when should pregnant women inject it to maximize the effect of the drug?
1. What is a lung maturation drug?
Two drugs that promote early lung development in the fetus are Betamethasone and Dexamethasone. These drugs belong to the group of corticosteroids, a group of drugs that promote lung maturation in the fetus.
Lung maturation medicine works by the following specific mechanism:
After injecting lung maturation into pregnant women, the drug will be transmitted through the bloodstream into the fetus and affect the lungs. Increases the ability of the lung to convert from pneumocytes I to pneumocytes II Synthesize and release more surfactant into the alveoli, helping to reduce the surface tension of the alveolar fluid layer, resisting the elastic force of the lungs. Helps to increase lung volume and reduce the amount of fluid inside the lungs After the injection of lung maturation, pregnant women often have signs of mild hyperglycemia for about 5 days, so before injection should be screened for diabetes to avoid complications. symptoms of gestational diabetes. If the pregnant woman is having gestational diabetes, she should stay in the hospital for treatment and monitoring after the injection.
Trắc nghiệm: Bạn có hiểu đúng về dấu hiệu mang thai sớm?
Các dấu hiệu mang thai sớm không phải chỉ mỗi trễ kinh mà còn có rất nhiều dấu hiệu khác như xuất huyết âm đạo, ngực căng tức,… Điểm xem bạn biết được bao nhiêu dấu hiệu mang thai sớm thông qua bài trắc nghiệm này nhé!
2. Effect of drugs on lung maturation
For babies born prematurely from 28-34 weeks, some internal organs in the baby's body are not fully developed, especially the lungs. Premature babies often have many health problems such as weak immune system, digestive disorders, low blood pressure, blood disorders such as anemia, jaundice, blood infections,... and especially problems. serious respiratory problems.
Trẻ sinh non thường có hệ miễn dịch yếu, dễ mắc bệnh
To minimize dangerous complications on the respiratory system, doctors often appoint pregnant women to inject lung maturation shots if there is a phenomenon of premature birth or threat of premature birth.
In general, lung maturation injection is effective in promoting fetal lung development to prevent respiratory complications in premature infants.
3. When should lung maturation drugs be injected?
Any pregnant woman wants her baby to develop fully and comprehensively before birth. However, this does not mean that pregnant women abuse this drug to stimulate lung development for the fetus. Lung maturation injections should only be used when prescribed by a doctor for pregnant women who are threatened with premature birth and are at risk of preterm birth. So when should adult lung injections for the best effect?
For pregnant women diagnosed at risk of preterm birth, this drug should be injected at 24-34 weeks of pregnancy if there is a risk of preterm birth within 7 days, note after 34 weeks of adult injection the lungs will no longer have much of an effect so injections are not necessary to avoid waste and unwanted side effects.
Dosage for lung maturation injection is as follows:
Betamethasone 12mg (Diprospan (5+2)mg): Inject 2 times intramuscularly, 24 hours apart. Dexamethasone 6mg: 4 doses intramuscularly, 12 hours apart.
4. Undesirable side effects of lung maturation drugs
Lung maturation injections for fetuses with signs of preterm birth are essential to avoid respiratory complications. However, using this drug also has a few side effects as follows:
The drug belongs to group C ie the group with side effects according to the conventions of the US Food and Drug Administration. Therefore, pregnant women should use the correct dosage as prescribed by the doctor, avoid using too much or less than the prescribed dose; When injected, lung maturation drugs often increase the risk of infection in pregnant women after giving birth; Causes high blood sugar within 5 days, pregnant women need to be monitored extremely carefully to avoid having gestational diabetes, causing dangerous complications for both mother and child; After the injection of lung maturation, the fetus tends to be less active, at risk of having a child with hyperactivity disorder after birth; After the injection, the child has a slow weight gain, the head circumference decreases due to early ossification of the cartilages or early fusion of the skull.
Trẻ sinh ra có nguy cơ mắc rối loạn tăng động khi tiêm trưởng thành phổi
The pregnancy process is monitored by a team of highly qualified doctors Regular check-ups, early detection of abnormalities The package pregnancy helps to facilitate convenient for the birthing process Newborns get comprehensive care
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