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Atridox drug has the main ingredient Doxycycline, a synthetic broad-spectrum antibiotic derived from oxytetracycline. Atridox is used in dentistry for the treatment of chronic periodontitis in adults. So to find out specifically what drug Atridox is? how does it use? Join us to find out the necessary information about the effects of Atridox through the article below.
1. The effect of the drug Atridox
1.1. What is Atridox? Atridox is a prescription drug - ETC manufactured by Den-Mat Holdings, LLC. The drug ATRIDOX contains ingredients and is packaged as a KIT.
Atridox is a product of Atridox® which is a controlled release product that includes a two syringe mixing system. Syringe A contains 450 mg of ATRIGEL ®, syringe B contains 50 mg of doxycycline hyclate, equivalent to 42.5 mg of doxycycline. The product formed is a pale yellow to yellow viscous liquid with a concentration of 10% doxycycline hyclate. Upon contact with perineal fluid, the liquid product solidifies and then allows a controlled release of the drug for a period of 7 days.
1.2. What does Atridox do? Atridox is used in the treatment of chronic periodontitis in adults to increase clinical attachment, reduce exploration depth, and reduce bleeding during exploration.
2. How to use Atridox?
Atridox is a product whose dosage varies depending on the size, shape and number of bags handled.
Preparation for use:
If refrigerated, remove product from refrigerator at least 15 minutes before mixing. Pair Syringe A (liquid delivery system) and Syringe B (powder medicine). Inject the liquid component of Syringe A (indicated by the red stripe) into Syringe B (doxycycline powder) and then push the liquid back into Syringe A. This entire operation is a mixing cycle. Complete 100 mixing cycles at a rate of one cycle per second using quick strokes. If immediate use is desired, proceed to step 7. If necessary, paired syringes can be stored at room temperature for up to three days. Some Atridox systems are packaged in resealable bags that can be used for this purpose. If the Atridox system is packaged in a tray, use an airtight container. After storage, perform an additional ten mixing cycles immediately before use. Continue with instructions for use immediately. The contents will be in Syringe A (indicated by the red stripe). Hold the paired syringe vertically with Syringe A at the bottom. Pull the plunger of Syringe A back and let the container flow down the barrel for a few seconds. Unchain the two syringes and attach one of the catheters provided to Syringe One.
3. Contraindications of the drug Atridox
Atridox must not be used in patients who are hypersensitive to doxycycline or any other drug in the tetracycline group.
4. Notes when using Atridox
Atridox has also not been clinically tested in pregnant women.
Atridox has not yet been clinically evaluated in patients with extremely severe periodontal defect-related conditions with very little residual periodontitis.
Atridox has not been clinically tested for use in alveolar bone reconstruction, in preparation for or in conjunction with the placement of dental implants, or in the treatment of implant failure.
Atridox has not been clinically tested in immunocompromised patients (such as patients immunocompromised due to diabetes, chemotherapy, radiation therapy, or HIV infection).
As with other antibiotic preparations, Atridox therapy may lead to overgrowth of non-susceptible organisms, including fungi.
Atridox should be used with caution in patients with a history of or predisposition to oral candidiasis. The safety and efficacy of Atridox have not been established for the treatment of periodontitis in patients with coexisting oral candidiasis.
Mechanical oral hygiene procedures (eg, brushing, flossing) should be avoided on any treatment area for 7 days.
Avoid excessive sunlight or artificial UV light while receiving doxycycline.
Doxycycline may decrease the effectiveness of birth control pills.
For nursing mothers
Tetracycline appears in breast milk after oral administration. It is not known whether doxycycline is excreted in human milk following administration of Atridox. Because of the potential for serious adverse reactions in nursing infants from doxycycline, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
For children
The safety and effectiveness of Atridox in pediatric patients have not been established. Oral doses of doxycycline in children up to 8 years of age have caused permanent discoloration of teeth.
5. Atridox side effects
Atridox can cause serious side effects including: Difficulty breathing, swelling of the face, lips, tongue or throat, loosening of teeth, jaw pain, severe dizziness. Get medical help right away, if you have any of the symptoms listed above.
The most common side effects of Atridox include:
Gum discomfort Pain, soreness or toothache Tell your doctor if you have any side effects that bother you or that don't go away.
6. How to store Atridox?
Store at 2° – 30°C (36° – 86°F).
Check the drug expiration date. When not in use, the drug should be collected and disposed of according to the instructions of the manufacturer or the person in charge of medicine. Conventional drugs are stored at room temperature, avoiding direct sunlight or high temperature, which can cause metabolism of the ingredients in the drug.
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