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B vitamins are a group of vitamins essential for good health. Your body can't store B vitamins for long, so you have to get them every day through what you eat and drink.1. What are B vitamins?
B vitamins are a water-soluble vitamin that plays an important role in cell metabolism and red blood cell synthesis. Although these vitamins share the same name (vitamin B1, B2, B3,...), they are chemically distinct compounds that often coexist in the same foods.Vitamin B complex supplements include all the essential B vitamins in one pill. Some contain 100% of the recommended daily amount of B vitamins (RDA). Many people get all of the B vitamins they need from a varied, healthy diet, but others get their B vitamins from supplements.
2. The role of vitamin B in health
B vitamins help the body convert food into energy (metabolism), create new blood cells, and maintain skin cells and connective tissues in the body.There are eight types of B vitamins, each with its own function: Thiamin (vitamin B1), Riboflavin (vitamin B2), Niacin (vitamin B3), pantothenic acid (vitamin B5), Vitamin B6, Biotin (vitamin B7), Folate ( vitamin B9), vitamin B12.
All of these are called vitamin B complexes. B vitamins often coexist in the same food. Many people can get enough of the B vitamins they need by eating a variety of nutrient-dense foods. However, people who have difficulty consuming such foods can use supplements.
People can develop a vitamin B deficiency if they don't get enough vitamins from their diet or supplements. They can also become deficient if their bodies cannot properly absorb nutrients or if their bodies get rid of too many of them due to certain health conditions or certain medications. Here, we will learn about some common drug interactions when using B-complex vitamins.
3. Some drug interactions of B-complex vitamins
3.1. Dimercaprol Drug Interactions How it interacts: Some B-complex vitamins contain iron. Meanwhile, dimercaprol can bind to iron. The complex of dimercaprol and iron is toxic and can harm your kidneys.What you should do about this interaction: Tell your healthcare professionals (eg doctor or pharmacist) right away that you are taking these medicines at the same time. Your doctor may ask you to stop taking iron-containing B multivitamins while you are taking dimercaprol. They will likely check your kidney function.
3.2. Bortezomib drug interactions Bortezomib is an anti-cancer drug. This drug can interact and cause very harmful effects if taken with B complex vitamins because vitamin C can be contained in vitamin B complex.
How the interaction occurs: Vitamin B supplements can contain vitamin C. may contain ascorbic acid, or vitamin C, which may decrease the effectiveness of bortezomib in treating cancer.
What you should do about this interaction: Make sure your healthcare professionals (eg doctor or pharmacist) know that you are taking these medicines at the same time. Don't take vitamin B supplements that contain vitamin C without first talking to your doctor if you have cancer. Your doctor may direct you to take your supplement at a specific time of day. Please follow these instructions closely.
3.3. Interaction with Levodopa Levodopa is a drug used in the treatment of Parkinson's disease and often needs to be combined with Carbidopa to improve the effectiveness of treatment. Supplementing with vitamin B6 over 5 to 10 mg per day will decrease the effectiveness of Levodopa.
How the interaction occurs: When vitamin B6 and Levodopa are taken together, absorption of Levodopa may be reduced if the dose of vitamin B6 is too high. At that time, the therapeutic effect of Levodopa may decrease and increase the symptoms of Parkinson's disease.
What you should do about this interaction: Contact your healthcare professionals (doctor or pharmacist) about taking these two medicines together. If your doctor prescribes these medicines together, you may need to separate the time you take each. If you notice an increase in your symptoms of Parkinson's disease, tell your doctor right away. Your Levodopa dose may need an adjustment.
3.4. Interaction with Tetracyclines Tetracyclines is an antibiotic used to treat certain infections such as acne, cholera, Brucella, syphilis,...
How the interaction occurs: Some B vitamins such as vitamins B5 may interfere with the absorption and effectiveness of tetracycline antibiotics. When these two drugs are taken together, your body may not be able to process the antibiotic properly. The level of the antibiotic in your blood can drop and decrease its ability to treat an infection.
What you should do about this interaction: Contact your healthcare professionals (doctor or pharmacist) as soon as possible about taking these two medicines at the same time. All vitamin B complex supplements work by the above mechanism, so they should be taken at different times with tetracycline. If your doctor prescribes these medicines together, take them at least 2 hours apart.
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