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Chlorpheniramine 4mg is the preferred drug group indicated for the treatment of symptoms of allergic diseases such as urticaria, angioedema, rhinitis .... So what is Chlorpheniramine 4mg drug and the drug should be used in doses How much is the right amount?
1. What is the use of Chlorpheniramine 4mg?
1.1. What is Chlorpheniramine 4mg? Chlorpheniramine medicine has the main ingredient chlorpheniramine 4 mg, and excipients just enough 1 tablet. Chlorpheniramine 4 mg medicine is prepared in the form of long tablets, packaged in a box of 10 blisters, each blister has 20 tablets, or a box has 1 bottle, each bottle contains 200 Chlorpheniramine tablets.
Chlorpheniramine 4 mg, an alkylamine derivative, is a mild sedative antihistamine. Antihistamine effects of the drug component Chlorpheniramine 4mg through competitive blocking of H1 receptors of effector cells. Chlorpheniramine is a drug used to treat symptoms and allergic diseases such as: urticaria, angioedema, allergic rhinitis, allergic conjunctivitis, itching, in combination with other drugs used to treat treat cough or cold symptoms.
1.2. What is Chlorpheniramine 4mg used for? Chlorpheniramine is used to treat seasonal and year-round allergic rhinitis. Other allergic symptoms such as: Urticaria, histamine vasomotor rhinitis, allergic conjunctivitis, contact dermatitis, angioedema, Quincke's edema, food allergy, blood reaction bar. Treat insect stings, or relieve itching, in patients with measles or chickenpox.
2. Usage of Chlorpheniramine 4mg
For adults and children older than 12 years: 1 tablet every 4 to 6 hours. The maximum daily dose is: 6 tablets (equivalent to 24mg) in 24 hours of the day.
In the elderly there may be an increased susceptibility to anticholinergic effects on the nervous system. Consideration should be given to a lower daily dose in the elderly (eg, a maximum of 12 mg in 24 hours).
Children from 6 years to 12 years: take 1/2 tablet every 4 to 6 hours. The maximum daily dose is: 3 tablets (equivalent to 12mg) in 24 hours of the day.
Chlorpheniramine 4mg drug content is not suitable for use in children under the age of 12.
Note: The dosage of Chlorpheniramine 4mg above is for reference only. This specific dose depends on the condition and the progression of the disease. To be able to use the right dose, patients need to consult a specialist or medical professional.
Handling when missed dose: If you miss a dose of Chlorpheniramine 4mg, the patient should take the medicine as soon as possible. But if it is almost time for your next dose, just take the next dose. Do not take a double dose or add an extra dose to make up for a missed dose.
Treatment in overdose: Manifestations of chlorpheniramine overdose are: sedation, psychosis, seizures, respiratory arrest or convulsions, antisecretory effects of acetylcholine and dystonic reactions, cardiac arrest pulse and arrhythmia.
Treatment: Need to wash the stomach, induce vomiting with syrup Ipecacuanha. Then, give the patient activated charcoal or bleach to limit absorption. If hypotension or arrhythmias occur, the patient needs to be treated aggressively. Convulsions can be treated with intravenous Diazepam or Phenytoin. Blood transfusions may be required in severe cases.
3. Contraindications of Chlorpheniramine 4mg
Chlorpheniramine 4mg drug is contraindicated in the following cases:
Patients with hypersensitivity to Chlorpheniramine 4mg drug, the main ingredient chlorpheniramine or any ingredient in the excipients of the drug. The patient is having an acute asthma attack. Symptoms of an enlarged prostate. Narrow angle glaucoma. Bladder neck obstruction. Gastric ulcer, pyloric - duodenal obstruction. Breastfeeding people or infants and premature babies. The patient is taking a monoamine oxidase (MAO) inhibitor within 14 days of the time it is time to start treatment with chlorpheniramine. 3.1 Drug Interactions Monoamine oxidase inhibitors prolong and potentiate the antimuscarinic effect of antihistamines.
Ethanol or hypnotic sedatives may enhance the CNS depressant effects of chlorpheniramine 4mg.
Chlorpheniramine 4mg inhibits the metabolism of phenytoin and can lead to phenytoin toxicity.
CYP3A4 inhibitors such as: dasatinib, pramlintide increase the concentration or effect of chlorpheniramine.
Drugs that reduce the effects of cholinesterase and betahistine inhibitors. Patients receiving monoamine oxidase (MAO) inhibitors within 14 days of treatment with chlorpheniramine because the antimuscarinic properties of Chlorpheniramine are enhanced by MAO inhibitors.
3.2 Pregnancy Use only when clearly needed. Taking Chlorpheniramine 4mg during the third trimester of pregnancy can lead to serious reactions (such as seizures) in the newborn.
3.3 Lactation: Chlorpheniramine 4mg can be excreted in breast milk and inhibits lactation. Therefore, consider not using the drug during this time.
4. Note when using Chlorpheniramine 4mg
The drug increases the risk of urinary tract infections in people with an enlarged prostate, urinary tract obstruction, pyloric obstruction or myasthenia gravis.
The sedative effect of Chlorpheniramine 4mg is increased when alcohol is taken or taken concomitantly with other sedatives.
There is a risk of respiratory complications, respiratory depression and apnea in people with pulmonary obstruction or young children. Use caution in the presence of chronic lung disease, shortness of breath or difficulty breathing.
There is a risk of tooth decay in patients with long-term treatment.
Avoid use in patients with glaucoma such as glaucoma.
May cause drowsiness, dizziness, dizziness, blurred vision and psychomotor impairment in some patients.
Elderly.
Should not be used in patients with galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption. Patients should be monitored when using the drug because the drug contains the yellow excipient tartrazine, which can cause allergic reactions.
5. Possible side effects of Chlorpheniramine 4mg
Common: Somnolence, sedation, dry mouth. Rare: Dizziness, nausea. In the process of using Chlorpheniramine 4mg, patients may also experience some unwanted side effects such as:
Blood and lymphatic system disorders: Hemolytic anemia, hematopoietic disorders. Immune system disorders: Allergic reactions, angioedema, anaphylactic reactions. Metabolic and nutritional disorders: Anorexia Psychiatric disorders: Confusion, irritability, irritability, nightmares, colds. Nervous system disorders: Sedation, drowsiness, Attention disorder, abnormal coordination, headache dizziness. Eye disorders: Blurred vision Ear and inner ear disorders: Tinnitus Cardiovascular disorders: Palpitations, tachycardia, arrhythmia. Vascular disorders: Hypotension. Respiratory, thoracic and mediastinal disorders: increased bronchial secretions. Digestive disorders: Nausea, dry mouth, Vomiting, abdominal pain, diarrhea, dyspepsia. Hepatobiliary disorders: Hepatitis, jaundice. Skin and Subcutaneous Disorders: Exfoliative dermatitis, rash, urticaria, photosensitivity. Musculoskeletal and connective tissue disorders: Muscle twitching, muscle weakness. Renal and urinary disorders: Urinary retention. General disorders: Fatigue, Chest tightness. Inform your doctor about any unwanted effects you may experience while using the drug.
The above is important information about Chlorpheniramine 4mg, before using, patients should actively learn and use the drug according to the instructions of a specialist doctor to get the best results. .
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