Pifeltro: Uses, indications and precautions when using

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Pifeltro is also used under the name Doravirine. It is used in combination with other products to help treat HIV, thereby reducing the amount of virus in your body. In addition, this drug can help control the source of HIV infection.

1. What effect does Pifeltro have?

Pifeltro is often prescribed by doctors to be used with other HIV medicines. The drug is effective in controlling the source of HIV infection. In addition, the drug also helps to reduce the amount of HIV in the patient's body, thereby helping to improve the body's immune system. This reduces your risk of HIV complications (such as new infections, cancer) and improves your quality of life. Doravirine is classified as a non-nucleoside reverse transcriptase inhibitor (NNRTI). However, Doravirine is not considered a cure for HIV infection.
HIV is a concern of the whole society. Therefore, to reduce the risk of HIV transmission in the community you need to do the following:
Take the medicines you have prescribed for you regularly Use safe methods of contraception during sex (latex or polyurethane condoms, dental dams) Do not share personal items with an HIV-infected person, as these items may be contaminated with the patient's blood or mucus (toothbrushes, face towels, etc.) razor...) 2. How to use Pifeltro Pifeltro drug is used orally, the drug can be combined with food or not with a dose of once per day. The dose of each person's medicine is calculated based on your health condition, the body's ability to respond to the treatment and other drugs you are taking.
You need to follow the instructions that your doctor has ordered and use the medicine regularly every day. You should never stop taking your medicine on your own and try not to miss any dose. To help you remember, set a notification to take your pill at the same time every day on your phone.

3. Side effects when using Pifeltro

During the use of the drug you may experience unwanted side effects such as:
Nausea Headache Fatigue Abdominal pain Diarrhea Dizziness or unusual dreams Other serious symptoms such as: change in mind mental or emotional state (such as depression, rarely suicidal thoughts, strange thoughts, anxiety). Use of drugs that can change the amount of body fat (such as increased fat in the upper back and stomach area, decreased fat in the arms and legs). Severe allergic reaction, signs of which include: rash, itching or redness (especially of the face, tongue or throat), severe dizziness, trouble breathing). If the above symptoms do not show signs of improvement or become increasingly severe, you need to take the patient to a medical facility immediately to receive timely help. When you are asked to use this medicine, your doctor knows that the benefits of the medicine outweigh the side effects. There are many use cases where only minor side effects appear.
As your immune system improves, your body begins to be able to fight off infection-causing agents, which can cause some disease symptoms to appear. This phenomenon can also occur when the immune system is overactive and occurs at any time, even in people who are new to treatment or those who have been on long-term treatment.
Take the patient to the nearest hospital for medical help if the patient has symptoms, including:
Unexplained weight loss Body becomes severely fatigued Muscle pain or weakness go away, severe headache that doesn't go away Joint pain Numbness or tingling in hands, feet, arms and legs Vision changes Signs of infection (such as fever, chills, swollen lymph nodes , shortness of breath, cough, skin sores that won't heal) Signs of an overactive thyroid (such as irritability, nervousness, heat intolerance, fast or pounding or irregular heartbeat) Signs of a certain nerve problems called Guillain-Barre syndrome (such as trouble breathing or swallowing or moving your eyes, drooping eyelids, paralysis, trouble speaking), signs of liver disease (such as vomiting that doesn't stop, loss of appetite, abdominal pain, jaundice and mucous membranes, dark urine). The above is only a reference list, for detailed information you should contact your treating doctor.

4. Precautions

Before using Pofeltro, you need to pay attention to a few things to help you avoid the side effects that the drug causes:
Tell your doctor about any allergies you may experience (the ingredients). of drugs, food, pollen, etc.). In the composition of the drug contains some inactive substances, these substances can affect the health of the user. Tell your doctor or pharmacist your and your family's medical history, especially of: liver problems (such as hepatitis B or C, cirrhosis). Users of the drug may experience dizziness. Subjects using alcohol or marijuana, this symptom may appear more severe. Do not drive, do anything that requires high concentration immediately after taking the drug. While taking the drug, the patient should limit the use of alcoholic beverages. Before surgery, give your doctor a list of all medications you are taking (prescription, over-the-counter, supplement). Pregnant women are advised by doctors to use the drug only when absolutely necessary. Early treatment can reduce a child's risk of HIV transmission. Breast milk is one of the routes of HIV transmission, so breast-feeding is not recommended if the mother is HIV-infected.

5. Drug interactions

Once a drug interaction occurs, the mechanism of action of the product will be changed, thereby increasing the risk of serious side effects. To reduce this risk you should not start taking it yourself or stop or change the dose of any medicine without your doctor's approval.
Some drugs that affect the removal of doravirine from your body include: apalutamide, enzalutamide, mitotane, rifampin, St. John's wort, medicine to treat seizures (such as carbamazepine, phenobarbital, phenytoin, primidone).

6. Storage and preservation

The drug should be stored at room temperature, in a dry place. Avoid keeping the medicine in the bathroom and places with high temperatures, this can cause the medicine to become damp and moldy, thereby reducing the quality of the medicine. Do not leave the medicine in direct sunlight, keep it out of reach of children and pets.

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Reference source: webmd.com