Noxafil drug: Uses, indications and notes when using

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Noxafil belongs to the group of azole antifungal drugs, which work by preventing the growth of fungi. Patients should strictly follow the doctor's instructions when using the drug to achieve effective treatment.

1. What does Noxafil do?

Noxafil belongs to the group of azole antifungal drugs, which prevent the growth of fungi. It is used to prevent certain fungal infections in severely immunocompromised patients (who have received chemotherapy). It is also used to treat fungal infections of the mouth and throat.

2. How to use Noxafil

Patients should carefully read the instructions for use or strictly follow the instructions of the doctor before starting to take Noxafil. How to use Noxafil is as follows:
Take it by mouth with a full meal as directed by your doctor. If it is not possible to take it with a full meal, the patient should take it with a liquid nutritional supplement or a carbonated beverage. The bottle should be shaken well before drinking. Carefully measure the medicine with a special measuring spoon. The dosage and duration of use of Noxafil are prescribed by the doctor based on the patient's health condition and ability to respond to treatment. For the best therapeutic effect, the patient should take the medicine at the same time every day. Continue taking the medicine until the prescribed amount is used up, even if the symptoms have disappeared. Stopping medication too soon may not cure the disease completely. Noxafil tablets and suspensions are available in different dosages. Therefore, patients should not switch between forms of this medication without their doctor's approval. Tell your doctor if you have severe diarrhea or vomiting. In addition, if the condition does not improve or becomes worse, the patient should also inform the doctor. In case it is not possible to take the drug with a full meal, liquid nutritional supplement or carbonated beverage, the patient should also inform the doctor.

3. Side effects when using Noxafil

Nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, trouble sleeping or stomach pain are common side effects of Noxafil. If these side effects persist or get worse, the person should tell their doctor right away. Tell your doctor right away if you experience serious side effects after using Noxafil such as: Swelling of the hands and feet, signs of infection, weakness, unusual tiredness, muscle cramps, mood changes, easy bruising or bleeding, trouble breathing, increased thirst, frequent urination. Get the patient to the emergency room right away if you experience very serious side effects such as a fast or irregular heartbeat, fainting, severe dizziness; Noxafil can rarely cause serious liver disease. However, patients should notify their doctor immediately if they develop symptoms of liver disease such as nausea and vomiting that do not stop, loss of appetite, severe abdominal pain, yellow eyes, yellow skin, dark urine. Very rarely, a serious allergic reaction to Noxafil has occurred. However, if you have severe allergic symptoms such as itching or swelling in your face, tongue, or throat; rash; shortness of breath; severe dizziness, ... need to take the patient to the emergency room immediately. The above may not include all of the side effects of Noxafil. Therefore, when experiencing other side effects, patients should contact their doctor immediately.

4. Notes when using Noxafil

Before taking Noxafil, you should inform your doctor if you have any allergies or have a history of liver, heart, or kidney disease. Noxafil may affect your heart rate (long QT syndrome) and other symptoms such as dizziness and fainting. This risk is increased if you use diuretics or have excessive sweating, diarrhea, or vomiting. Therefore, if you experience the above conditions, you need to inform your doctor. Noxafil may cause dizziness. Therefore, the patient should not drive, use machinery or perform other tasks until it is safe to do so. Older adults are often more sensitive to the side effects of Noxafil. In pregnant women, use the drug only when absolutely necessary. Therefore, talk to your doctor about the benefits and risks of using this medicine. There is no evidence that Noxafil passes into breast milk. Therefore, breast-feeding women should consult their doctor before taking the drug.

5. Drug interactions

You should talk to your doctor about any medications you are taking before taking Noxafil. Also, do not start, stop, or change the dose of any medicine without your doctor's approval.
Some drugs that interact with Noxafil are:
Cimetidine; efavirenz; proton pump inhibitors (esomeprazole, pantoprazole); rifamycins (rifabutin); certain medicines to treat seizures (phenytoin). Noxafil may slow the elimination of other medicines from the body. Such drugs include: Alpha blockers (alfuzosin, silodosin, tamsulosin); benzodiazepines (midazolam); dronedarone; ergot alkaloids (ergotamine, dihydroergotamine); pimozide; quinidine; rivaroxaban; sirolimus; lovastatin; simvastatin,...

6. Some other notes

If you overdose on Noxafil and experience serious symptoms such as shortness of breath or fainting, the patient should be taken to the emergency room immediately. Do not share Noxafil with other people. Do not use Noxafil to treat or prevent other infections unless directed by your doctor. Tests such as liver function, calcium, magnesium, and potassium in the blood should be done before and during the use of Noxafil. If you forget a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take it at your usual time, do not take a double dose. Store Noxafil at room temperature, away from light and moisture, do not freeze, do not store in the bathroom, out of reach of children. At the end of the shelf life or when the medication is not needed, you need to dispose of Noxafil according to the instructions. In summary, when using Noxafil, patients need to take the right dose and recommended time to ensure the best treatment effect, avoiding the risk of unpredictable side effects.

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Reference source: Webmd.com