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Insulin Mixtard is an injectable suspension used to treat diabetes. Insulin Mixtard has a fairly quick effect, within 30 minutes after injection, it can lower blood sugar even more, patients using Insulin Mixtard may have to inject it regularly at home. Therefore, it is important to keep in mind the notes when using the drug to avoid unwanted effects during the use of insulin mixtard.
1. What is Mixtard Insulin?
Insulin Mixtard is a suspension for injection containing the active ingredient human insulin. It is available as a vial, box (Penfill) or pre-filled pen (InnoLet or FlexPen). Mixtard insulin contains both rapid acting (soluble insulin) and long acting insulin (insulin isophane) including:
Insulin Mixtard 30 contains 30% soluble insulin and 70% insulin isophane Insulin Mixtard 40 contains 40% soluble insulin soluble and 60% insulin isophane Insulin Mixtard 50 contains 50% soluble insulin and 50% insulin isophane
2. How does Insulin Mixtard work?
Diabetes is a disease in which the body does not produce enough insulin to control blood sugar or when the body cannot use insulin effectively. Insulin Mixtard is an insulin replacement that is very similar to the insulin made by the pancreas.
The active ingredient in Mixtard is human insulin, produced by a method known as “recombinant technology”: the insulin produced by yeast cells has been inserted into fragments of genes (DNA) that make them possible insulin production. Mixtard Insulin contains insulin in two forms: a soluble form, which acts quickly (within 30 minutes of injection) and "isophane", a form that is absorbed much more slowly and lasts all day. This gives Mixtard Insulin a longer action time. Replacement insulin works similarly to naturally produced insulin and helps glucose get into cells from the bloodstream. By controlling blood glucose, the symptoms and complications of diabetes will be reduced.
3. In what cases is Insulin Mixtard used?
You can use Insulin Mixtard in the following cases:
Type 1 diabetes (insulin dependent) Type 2 diabetes After making lifestyle adjustments, diet and taking a combination of drugs oral hypoglycaemia maximum dose without reaching the goal of treatment (bringing HbA1C from 6.5-7.0% in 3 months.) Emergency treatment of patients in pre-coma, diabetic coma. overweight, malnourished, accompanied by infections. Preparing for surgery, during surgery. There are serious complications such as liver failure, severe kidney failure, myocardial infarction, retinopathy, severe cardiovascular disease. Gestational diabetes.
4. In what cases should you not use Insulin Mixtard?
You should not use Insulin Mixtard if:
You have a history of allergy or hypersensitivity to any ingredient of Insulin Mixtard You have low blood sugar Have kidney problems or kidney failure Low or low blood potassium Other health problems may affect the operation of Mixtard. Therefore, you should inform your doctor about your history of allergies and health conditions to be considered about the use of the drug.
4. How to take Insulin Mixtard?
Mixtard is injected under the skin, into the thighs, abdominal wall (in front of the waist), buttocks or deltoid area of the shoulder. The injection site should be changed each time to reduce the risk of lipodystrophy. Your blood sugar should be checked regularly to find the lowest effective dosage level.
The usual daily dose is between 0.3 and 1.0 international units (IU) per kilogram of body weight.
Insulin Mixtard is taken 30 minutes before a meal. The drug can be used once or twice daily. However the medication is usually given once or twice a day. In addition, your doctor may recommend other ways to use your medication depending on your age, health condition, and specific symptoms to get the most out of it and avoid potential risks. born.
5. What should be noted when using Insulin Mixtard?
Remember Insulin Mixtard is a medicine to be used only by prescription. Read the instructions carefully before using the medicine, if you have any questions, consult your doctor. Regularly check your blood sugar while using Insulin Mixtard to avoid hypoglycemia. symptoms of hypoglycemia such as: feeling of hunger, fatigue, sweating, hand tremors, palpitations, coma, ... Use the drug according to the prescribed dose, not voluntary discontinuation of the drug, especially with type 1 diabetes, as this may cause hyperglycaemia. Symptoms of hyperglycemia such as thirst, nausea, vomiting, dry skin, dry mouth, and acetone breath may appear gradually, last from a few hours to several days, and can lead to death. There are no restrictions on the use of Insulin Mixtard to treat pregnant women, but you should still consult a specialist before using the drug. Some special notes when using Insulin Mixtard in pregnant and lactating women are as follows: The process of insulin injection for pregnant women requires careful instruction and monitoring, pregnant women will use the kit. home blood glucose monitor to monitor and record blood sugar 4 times per day. Record the specific number of insulin units used in each injection and the total daily dose. The insulin dose requirement for pregnant women increases with gestational age. Around the 32nd week of pregnancy a non-stress test is done to check for signs that the fetus is getting enough blood from the placenta. Get regular ultrasounds to check your baby's growth rate. Use of Insulin Mixtard in lactating women does not pose any risk to the mother or the baby; however, a dose adjustment is required for both.
If you are doing things such as driving, operating machinery, your concentration may be affected by hypoglycemia, so be careful to avoid this situation while working, stop working immediately. doing and where you can call for help when needed.
Consult your doctor before traveling to a time zone difference, as you will have to inject insulin and take meals at a different time.
Excessive and irregular exercise without changing your carbohydrate intake can cause low blood sugar hours after exercise, instead exercise regularly and as directed by your doctor.
Be cautious when drinking alcoholic beverages as they can lower your blood sugar and affect how your medications work
Inform family and friends about the symptoms of hypoglycemia so they can help you if you start experiencing it.
Do not use when Insulin Mixtard has signs of deterioration, discoloration or expiration
6. What are the risks of Mixtard Insulin?
The most common side effect of Mixtard insulin is to cause hypoglycemia and some other side effects during the time of taking the drug such as:
Itching Rash Red skin Hardening of the skin Urticaria Atrophy/hypertrophy of fat tissues Reactions Anaphylaxis The above information does not include all the side effects of Insulin Mixtard, you may experience other effects, if there is any abnormality during the use of the drug that makes you worried, please contact us. with your doctor.
7. Some drugs to be aware of when using with insulin mixtard
Certain medications can reduce your insulin needs:
Oral antidiabetic drugs Monoamine oxidase inhibitors (MAOIs) Nonselective beta blockers Angiotensin-converting enzyme (ACE) inhibitors Salicylate Anabolic steroids Certain substances can increase your insulin needs:
Oral contraceptives Thiazide Glucocorticoid Thyroid hormone Growth hormone Insulin Mixtard in the refrigerator (2°C - 8°C) According to experts. Keep the medicine away from the refrigeration unit and do not freeze. Keep Insulin Mixtard away from excessive heat or light. While in use, the shelf life is 5 weeks when stored below 30°C or 6 weeks when stored below 25°C. Do not keep in the refrigerator after opening the medicine for the first time or bring a spare.
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