Lifedroxin drug use

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1. What is Lifedroxin?

What is Lifedroxine? Lifedroxin medicine has the main active ingredient is Cefadroxil with the strength of 500mg and other excipients in sufficient quantity. This drug is in the form of capsules, suitable for direct oral administration. This is an antibiotic indicated in the treatment of respiratory tract infections, urinary tract infections,...
Packing is a box of 10 blisters and each blister includes 10 capsules.
1.1. Pharmacodynamics of active ingredient Cefadroxil Active ingredient Cefadroxil is a first-generation Cephalosporin antibiotic.
1.2. Pharmacokinetics of the active substance Cefadroxil Absorption: The active substance Cefadroxil is rapidly and completely absorbed following the direct oral route. Food does not affect the absorption of active ingredients Cefadroxil. Following single oral administration of 500 mg and 1 g, mean peak serum concentrations were approximately 16 and 28 mcg/mL respectively. Blood levels of the drug are still measurable about 12 hours after oral administration. Distribution is very high in tissue because it is soluble in fat. Elimination: More than 90% of the drug is excreted unchanged in the urine after 24 hours. 1.3. Effect of active ingredient Cefadroxil Active ingredient Cefadroxil has a medium spectrum of activity, effective against gram-positive bacteria such as staphylococcus, streptococcus, pneumococcus, except methicillin-resistant streptococcus. This active ingredient is also effective against some gram-negative bacteria such as E.coli, Klebsiella pneumoniae, Proteus mirabilis and Shigella. The mechanism of action of the active ingredient Cefadroxil is to inhibit bacterial cell wall synthesis, the drug has a bactericidal effect that inhibits the final stage of bacterial cell wall synthesis, leading to bacteria without a protective wall. be destroy. Bacterial strains resistant to cefadroxil: Enterococcus, methicillin-resistant Staphylococcus, Proteus with positive indole reaction, Enterobacter, Pseudomonas aeruginosa, Bacteroid.

2. What disease does Lifedroxin treat?

What disease does Lifedroxin treat? Lifedroxin is indicated for the treatment of infections caused by the following susceptible microorganisms:
Urinary tract infections including acute and chronic pyelonephritis, cystitis, urethritis. Respiratory tract infections including tonsillitis, pharyngitis, bronchopneumonia and lobar pneumonia, acute and chronic bronchitis, pleurisy, lung abscess, empyema, laryngitis or otitis Between. Skin and soft tissue infections, such as lymphadenitis, abscess, cellulitis, ulcer. Osteomyelitis, septic arthritis.

3. Usage and dosage of Lifedroxin

3.1. How to use Lifedroxin Lifedroxin is made in the form of capsules, suitable for direct oral use. The active ingredient Cefadroxil is acid-stable and can be taken orally, regardless of meals. Taking with food may help relieve gastrointestinal symptoms that sometimes occur during treatment with oral cephalosporin antibiotics. 3.2. Dosage of Lifedroxin For adults: use 500mg - 1g/time orally 1 or 2 times a day depending on the degree of infection
For children:
Children 1-6 years old take 250mg, 2 times a day Children over 6 years old take 500mg, 2 times daily. Dosage adjustment is required for the elderly and patients with renal impairment. It should be noted: The above drug dosage is for reference only, patients need to take Lifedroxin exactly as directed by their doctor or pharmacist. Absolutely do not change the dose, or use more than prescribed with the desire to treat the disease faster.

4. Undesirable effects of the drug Lifedroxin

The main active ingredient Cefadroxil is very well tolerated at all ages. However, in a very small number of patients, the drug may have specific undesirable effects as follows:
Gastrointestinal disturbances: nausea, vomiting, diarrhea are less common. Hypersensitivity reactions: Rarely, rash, urticaria on the skin surface have been reported. These signs and symptoms will usually go away on their own after you stop using this medicine. Other adverse events that may occur with a rare frequency include genital pruritus, vaginitis, and transient neutropenia. The above is not exhaustive to all side effects and others that may occur. You need to pay attention to proactively notify your treating doctor for medical advice about side effects when using Lifedroxin.

5. Lifedroxin drug interactions

Interactions of Lifedroxin drugs that may occur during use are as follows:
Cholestyramine binds to the active ingredient Cefadroxil in Lifedroxin in the intestine, slows down the absorption of Probenecid, can reduce antibiotic excretion In the Cephalosporin Furocemid family, aminoglycosides can synergistically increase nephrotoxicity. Other drugs may interact with Lifedroxin. Lifedroxin drug interactions may change its ability to work or increase the effects of unwanted effects. It is important to proactively list all the prescription and over-the-counter medicines, herbal products or health foods you are taking to your attending physician or clinical pharmacist. used to minimize the types of interactions that may cause adverse effects on the health of the user. Lifedroxin drug interactions with foods and drinks: When using the drug with foods or alcohol, beer, tobacco... because in those foods and drinks containing other active ingredients, it may affect antagonism or synergistic effects with the drug. You need to actively read the instructions for use of the drug or consult your doctor, pharmacist about using Lifedroxin with food, alcohol and tobacco.

6. Some notes when using the drug Lifedroxin

In the process of using Lifedroxin, patients need to pay attention to some issues here.
6.1. Contraindications of the drug Lifedroxin Do not use the drug Lifedroxin for people who have a sensitive or hypersensitivity to Cephalosporin
6.2 antibiotics. Notes and precautions when taking Lifedroxin Use caution when using the drug in people who are allergic to the antibiotic Penicillin. Use with caution in people with kidney failure, people with gastrointestinal disease. Long-term use of drugs containing Cefadroxil, specifically Lifedroxin, may lead to overgrowth of non-susceptible strains. Attention should be paid to carefully monitor the patient, if superinfection, must stop using this drug. Store Lifedroxin in a dry place, at a temperature of 15 - 30 degrees Celsius in tightly closed containers, away from moisture and away from direct light. In addition, it is necessary to keep Lifedroxin medicine out of the reach of children and family pets. Absolutely do not use Lifedroxin after the expiry date. Consult environmental companies for how to dispose of medications.
In summary, Lifedroxin has the main active ingredient Cefadroxil 500mg and other excipients in sufficient quantities. This is an antibiotic indicated in the treatment of respiratory tract infections, urinary tract infections,... Patients should carefully read the instructions for use and consult a doctor/pharmacist before using it. drug use. Absolutely do not arbitrarily buy Lifedroxin to treat diseases at home, because there may be unwanted side effects on health.
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