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Cerebellar degeneration is one of the major neurological diseases caused by genetic factors. People with degenerative cerebellar disease often find it difficult to balance and their quality of life is severely affected. The disease has no cure yet.
1. What is cerebellar degeneration?
Cerebellar degeneration is a process in which nerve cells in the cerebellum deteriorate and die. Diseases that cause cerebellar degeneration can also involve other areas of the central nervous system, including the spinal cord, cerebral cortex, and brain stem. Cerebellar degeneration can be the result of inherited genetic mutations that alter the normal production of specific proteins required for neuronal survival.
2. Symptoms of cerebellar degeneration The most characteristic symptom of cerebellar degeneration is unsteadiness in walking, often accompanied by tremors in the body. Other symptoms may include slow, unsteady movements, shaky arms or legs, slurred speech, slurred speech, nystagmus, and rapid, small eye movements.
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3. Related diseases
Diseases specific to the brain as well as diseases occurring in other parts of the body can cause nerve cells in the cerebellum to die. Characteristic neurological diseases include:
Ischemic or hemorrhagic stroke when blood or oxygen is lacking to the cerebellum; Cerebellar cortical atrophy, multisystem atrophy, small platelet degeneration, progressive degenerative disorder in which cerebellar degeneration is the main feature; Friedreich's ataxia and other platelet ataxias caused by inherited genetic mutations lead to ongoing neuronal loss in the cerebellum, brain stem, and spinal cord; Infectious spongiform encephalopathy in which abnormal proteins cause inflammation in the brain, including the cerebellum; Multiple sclerosis, in which damage to the insulating membrane (myelin) that surrounds and protects nerve cells may involve the cerebellum. Acquired diseases that can cause cerebellar degeneration include:
Cerebellar degeneration is thought to be caused by alcoholism. Alcoholic cerebellar degeneration is one of the common neurological complications in alcoholics. The findings suggest that in alcoholic cerebellar degeneration, severe lesions develop sequentially in the anterior superior cerebral hemisphere, anterior inferior cerebral hemisphere, and anterior nodules. In addition, cerebellar symptoms can often occur if the upper and lower anterior hemispheres are involved. Paraneoplastic disorder, in which a malignant tumor in other parts of the body produces substances that cause cells of the immune system to attack nerve cells in the cerebellum
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4. Is cerebellar degeneration dangerous?
Currently, there is no cure for inherited forms of cerebellar degeneration. Therefore, this is a dangerous disease that needs to be detected early and treated promptly. Treatment is usually supportive and based on its symptoms. For example, medication may be prescribed to alleviate gait abnormalities. Physical therapy treatment can strengthen muscles. Other disorders that may contribute to cerebellar degeneration may have treatment options to ease symptoms.
In short, patients need to go to a reputable hospital to conduct examination and treatment as soon as there are signs of cerebellar degeneration. Currently, Vinmec International General Hospital is one of the leading prestigious hospitals in the country, trusted by a large number of patients for medical examination and treatment. Not only the physical system, modern equipment: 6 ultrasound rooms, 4 DR X-ray rooms (1 full-axis machine, 1 light machine, 1 general machine and 1 mammography machine) , 2 DR portable X-ray machines, 2 multi-row CT scanner rooms (1 128 rows and 1 16 arrays), 2 Magnetic resonance imaging rooms (1 3 Tesla and 1 1.5 Tesla), 1 room for 2 levels of interventional angiography and 1 room to measure bone mineral density.... Vinmec is also the place to gather a team of experienced doctors and nurses who will greatly assist in diagnosis and detection. early signs of abnormality in the patient's body. In particular, with a space designed according to 5-star hotel standards, Vinmec ensures to bring the patient the most comfort, friendliness and peace of mind.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
References: ninds.nih.gov, sciencedirect.com
