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Ketosan is a medication commonly used in the prevention of bronchial asthma and in the treatment of certain allergic conditions. What are the uses of Ketosan?1. What are the uses of Ketosan?
Ketosan medicine has the main ingredient Ketotifen 1mg. Ketotifen is a relatively selective, non-competitive histamine H1 inhibitor and a mast cell protectant. Ketotifen acts mainly on the respiratory system, it is a non-bronchodilator asthma medication and has anti-allergic effects.
Ketotifen inhibits the release of allergenic chemical mediators from mast cells and cells involved in allergic reactions such as histamine, leukotrienes C4 and 04 (SRS - A) and PAF.
The drug inhibits H1 receptors and inhibits the enzyme phosphodiesterase, resulting in increased levels of cAMP in mast cells.
Ketotifen prevents the development of respiratory allergies, inhibits platelet activation of PAF (platelet activating factor) or nerve excitability after administration of sympathomimetic drugs; inhibits eosinophil and platelet aggregation by respiratory PAF, and inhibits eosinophil proliferation, thereby inhibiting eosinophil influx into the inflammatory site.
Ketosan 1mg drug is indicated for use in the following cases:
Prevention of bronchial asthma such as asthma, asthma attacks, asthma in case of seasonal fever and allergic bronchitis. When starting treatment with Ketosan, the patient should continue to take the basic asthma medication: bronchodilators, theophylline or corticosteroids. Symptomatic treatment of allergic rhinitis, systemic allergy, atopic dermatitis, urticaria, rash, allergic conjunctivitis. Note: Ketosan is not indicated for the treatment of acute asthma attacks.
Ketosan 1mg drug is contraindicated in the following cases:
People with hypersensitivity to ketotifen and other components of the drug. Women who are pregnant in the first 3 months or are breastfeeding.
Thuốc Ketosan được sử dụng trong phòng ngừa hen phế quản
2. Dosage and how to use Ketosan
Ketosan is taken orally. Duration of treatment depends on the severity of each patient, there is no special limit, usually no less than 2-3 months.
Treatment with Ketosan should last at least a few weeks to have a clear therapeutic effect. The full clinical effect is usually achieved after 10 weeks of treatment with Ketosan.
Therefore, for patients who do not respond to treatment in the first few weeks should continue to maintain treatment for at least 2-3 months. If it is necessary to stop using Ketosan, the dose should be reduced gradually over 2 to 4 weeks before stopping completely and asthma symptoms may reappear.
Adults, adolescents and children > 3 years: Use 1 tablet (1mg) x 1 time / day in the evening with food for the first 3-4 days of treatment. The following days, will take 1 tablet (1mg) x 2 times / day in the morning and evening with food.
For adults and children > 10 years old: If the therapeutic effect is not achieved after 4 weeks of treatment, the maximum dose can be increased to 2mg (2 tablets)/time x 2 times/day.
Children 6 months - 3 years old (if necessary): Using a dose of 0.5mg x 2 times/day should use syrup form to drink.
In case of sensitivity to the sedative activity of the preparation, it is recommended to start with 1/2 dose (0.5 - 1 mg in the evening) for the first few days of treatment, then increase the dose gradually.
Overdose at a dose of 20 - 120mg Ketotifen will have symptoms of acute poisoning including drowsiness, somnolence, drowsiness, dizziness, disorientation, confusion, vomiting, difficulty breathing; tachycardia and hypotension , convulsions, especially in children; hyperactivity in children; fainting, coma.
When using Ketosan drug overdose will be handled by the following:
Can conduct gastric lavage or use activated charcoal. If symptomatic or specific treatment is required and the cardiovascular system is checked, use anticholinergic physostigmine, diuretics; If irritation or convulsions occur, use short-acting barbiturates or benzodiazepines. If you forget a dose of Ketosan, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled and do not take a double dose.
Người bệnh nên dùng thuốc Ketosan theo liều lượng bác sĩ chỉ định
3. Possible side effects when using Ketosan 1mg
When using Ketosan, you may experience the following side effects:
Gastrointestinal side effects include nausea, vomiting, epigastric pain, diarrhea. Common side effects include: Central nervous system depression with manifestations ranging from drowsiness to deep sleep, fatigue, dizziness, dizziness. These symptoms may subside after a few days of treatment with Ketosan. Uncommon side effects include: Central nervous system stimulation especially when used in high doses, children and the elderly such as irritability, insomnia, irritability, temper. Rare side effects include: Blood disorders: Leukopenia, agranulocytosis, hemolytic anemia, thrombocytopenia. In addition, the frequency is unspecified as follows:
Cardiovascular: Arrhythmia, palpitations. Skin: Skin rash, urticaria, severe skin reactions such as erythema multiforme, Stevens Johnson syndrome. Cystitis ; Hepatitis; Other: Headache, increased appetite and weight gain, psychomotor impairment, antimuscarinic manifestations such as dry mouth, increased bronchial secretions, blurred vision, dysuria or urinary retention, constipation, increased reflux stomach; sweating, convulsions, myalgia, extrapyramidal effects, tremor, sleep disturbance, depression, alopecia, tinnitus, decreased blood pressure. When experiencing side effects of Ketosan, you need to stop using it and notify your doctor or immediately go to the nearest medical facility for timely treatment. Ketosan is a medication commonly used in the prevention of bronchial asthma and in the treatment of certain allergic conditions. To ensure effective treatment, patients need to take medicine according to prescription or consult a doctor, pharmacist for advice.
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