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Carvedilol 6.25mg drug containing the active ingredient Carvedilol is indicated in the treatment of hypertension, heart failure and angina... Let's learn about the indications and effects of the drug Carvedilol 6.25 through the article below.
1. Uses of the drug Carvedilol 6.25mg
"What does Carvedilol 6.25mg do?". Carvedilol 6.25 drug containing the active ingredient Carvedilol in the form of film-coated tablets is indicated in the following cases:
Treatment of hypertension through a regimen alone or in combination with other drugs, especially diuretics. thiazides; Treatment of heart failure: In combination with diuretics, digoxin and angiotensin enzyme inhibitors in the treatment of moderate to severe congestive heart failure occurring due to cardiomyopathy or ischemic heart disease. Therapy aimed at reducing disease progression (as demonstrated by length of hospital stay, mortality, or other heart failure medication adjustments); Treatment of angina pectoris.
2. Dosage of Carvedilol 6.25mg
Carvedilol 6.25mg belongs to the group of prescription drugs, the dose used depends on the age, medical condition and should be prescribed by the treating doctor. Some recommendations on the dosage of Carvedilol 6.25 are as follows:
Adults:
Treatment of hypertension: The initial dose is 12.5mg/time/day, then increase the dose to 25mg/time/day after 2 days. Or the dose can be applied is 6.25mg / time x 2 times / day, after 7 days increase to 12.5mg / time x 2 times / day. If necessary, the dose may be increased at least 2 weeks apart to a maximum dose of 50 mg once daily or divided into several times a day. The recommended dose in the elderly is 12.5mg/time/day to effectively lower high blood pressure; Treatment of angina: The starting dose of Carvedilol is 12.5mg/time x 2 times/day, then increase the dose to 25mg/time x 2 times/day after 2 days; Treatment of heart failure: Before being treated with Carvedilol, patients should be stabilized with a standard regimen consisting of diuretics, cardiac glycosides, angiotensin converting enzyme inhibitors. The recommended dose of Carvedilol is 3.125 mg/time x 2 times/day for 2 weeks. The dose may then be increased to no more than 25 mg/time x 2 times/day for patients weighing less than 85 kg or with mild, moderate heart failure or not more than 50 mg/time x 2 times/day for severe patients. over 85kg or severe heart failure; Treatment of idiopathic cardiomyopathy: The recommended dose of Carvedilol is 6.25-25mg/time x 2 times/day. Children: The dose in the treatment of heart failure in children from 2 to 18 years old is 3.125 mg/time x 1-2 times/day for a maximum of 2 weeks. The dose if tolerated by the patient can be increased to a maximum of 25mg/time x 1 time/day.
Note that the dose of Carvedilol 6.25mg presented above is for reference only, the specific dose of Carvedilol prescribed by the treating doctor depends on the disease condition. Therefore, the patient absolutely should not self-medicate, but should use the drug exactly as prescribed by the doctor.
3. Carvedilol side effects
Carvedilol 6.25mg drug can cause some side effects as follows:
Common: Myalgia, headache, fatigue, dizziness, dyspnea, orthostatic hypotension, nausea; Uncommon: Diarrhea, bradycardia, abdominal pain; Rare: Leukopenia, thrombocytopenia, peripheral hypothermia, depression, syncope, sleep disturbance, vomiting, paresthesia, constipation, pruritus, urticaria, elevated liver transaminases, psoriasis, irritation, reduced tear secretion, stuffy nose.
4. Notes when using the drug Carvedilol
4.1. Contraindications Contraindicated to use Carvedilol in the following cases:
Patients with acute heart failure; Patients with decompensated congestive heart failure (NYHA class III - IV) have not been treated with standard regimen; Patients with bronchospasm, bronchial asthma; Patients with cardiogenic shock, atrioventricular block - second or third degree, severe bradycardia; Patients with severe liver failure, symptomatic liver failure; Hypersensitivity to Carvedilol or any of its ingredients. 4.2. Precautions for use Carvedilol should be used with caution in patients with congestive heart failure being treated with diuretics, digitalin or angiotensin-converting enzyme inhibitors. Use with caution in patients with uncontrolled or poorly controlled diabetes. Discontinue use of Carvedilol in case of signs of liver damage. Caution should be exercised when treating patients with anesthesia, patients with peripheral artery disease or thyrotoxic syndrome. In the absence of other antihypertensive agents, treatment with very small doses of carvedilol may be considered in hypertensive patients with chronic obstructive pulmonary disease. Avoid stopping Carvedilol suddenly (reduce the dose gradually over 1-2 weeks). A risk of cardiac arrhythmias may occur when Carvedilol is used concomitantly with anesthetic agents. For pregnant women: Carvedilol has been shown to cause clinical harm to the fetus. Therefore, the drug should only be used in the treatment of pregnant women when the desired benefits outweigh the risks and should be prescribed by a specialist. Note absolutely do not use the drug in the last 3 months of pregnancy or near delivery. Carvedilol can cause some unwanted effects on the fetus such as lowering blood pressure, bradycardia, lowering blood glucose, respiratory depression, lowering body temperature. For lactating women: Carvedilol is excreted in breast milk. Therefore, to limit the risk of harm to the baby, patients who are breastfeeding should not use the drug or are taking Carvedilol, they should stop breastfeeding.
5. Drug interactions
Carvedilol 6.25mg drug may cause some interactions as follows:
Concomitant use of Rifampicin and Carvedilol reduces the plasma concentration of Carvedilol by 70%; The effect of Carvedilol is reduced when used with the following drugs: Barbiturates, aluminum salts, Cholestyramine, Calcium salts, alpha-1 receptor blockers, Cholestyramine, Salicylate, Penicillin (Ampicillin), Sulfinpyrazone; Carvedilol enhances the effect of antidiabetic drugs, digoxin and calcium channel blockers; Clonidine interacts with carvedilol resulting in decreased heart rate and increased blood pressure[; The effect and bioavailability of Carvedilol is increased when co-administered with Cimetidine; Other drugs that can increase the concentration and effect of Carvedilol include Fluoxetin, Quinidine, Propafenin, Paroxetin; Carvedilol increases blood levels of Digoxin by 20% when taken at the same time. Drug interactions occur that reduce the therapeutic effect of Carvedilol, increasing the risk of unwanted effects. Therefore, patients need to inform the treating doctor of all medicines they are using (over-the-counter drugs, prescription drugs) and dietary supplements before being treated with Carvedilol to ensure safety and effectiveness. during treatment.
Carvedilol 6.25mg drug containing the active ingredient Carvedilol is indicated in the treatment of hypertension, heart failure and angina... To ensure effective treatment and avoid unwanted side effects, patients need to follow Follow the instructions of your doctor or pharmacist.
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