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Anti-thyroglobulin occurs when the immune system attacks the thyroid gland. The anti-thyroglobulin antibody test is indicated to check the level of antibodies in the blood, to assess the autoimmune status.
1. Antithyroglobulin . antibodies
The thyroid is a gland located in the neck that helps release hormones to control the body's metabolism. The thyroid gland makes a number of different proteins and that includes thyroglobulin. Thyroglobulin is used by the thyroid gland to make active thyroid hormones.When there is an autoimmune condition in the body, it disrupts the production of thyroglobulin and produces anti-thyroglobulin antibodies. An autoimmune condition occurs when the immune system produces antibodies that attack the body's own healthy cells. Therefore, high levels of anti-thyroglobulin antibodies in the blood may indicate an autoimmune condition.
2. Antithyroglobulin antibody test
Anti-thyroglobulin antibody test is usually ordered along with thyroglobulin test , for cases where there are symptoms of thyroid disorder such as:
Fatigue Unexplained weight gain Dry skin Constipation In addition , anti-thyroglobulin test is indicated in some cases such as:
Before surgery and periodically after surgery or I-131 treatment to assess the effectiveness of treatment and detect recurrence or metastasis of the cancerous tumor. differentiated thyroid cancer Growing goiter Enlarged thyroid gland Suspected autoimmune disorder. The patient will have a blood sample taken, and be careful not to eat or drink before the test. Stop some medications that can affect test results like warfarin, multivitamins,...
3. Meaning of test results
If the test result is negative, it means that there are no anti-thyroglobulin antibodies in the blood. If the result is positive, the body may experience some health problems such as:
Type 1 diabetes Pernicious anemia, decreased red blood cells due to vitamin B12 deficiency Collagen vascular disease such as: scleroderma, inflammation rheumatoid arthritis Thyroid cancer If high levels of anti-thyroglobulin antibodies in the blood can be a sign of a serious autoimmune disorder. In some cases, no cause can be found to cause a positive anti-thyroglobulin antibody test, the doctor will order health monitoring and order some other additional tests.
In short, anti-thyroglobulin antibodies appear when the body's immune system attacks healthy cells. Anti-thyroglobulin test is indicated to check the level of antibodies in the blood, to assess the body's autoimmune status.
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