Ibrance: ingredients, uses and notes when using

This is an automatically translated article.


Posted by Pharmacist Nguyen Mai Huong - Faculty of Pharmacy - Vinmec Times City International General Hospital

Ibrance is indicated for the treatment of hormone receptor-positive locally advanced or metastatic breast cancer – HR. To ensure the effectiveness of the treatment, the patient must strictly follow the instructions of the doctor.

1. The drug ibrance is the treatment of choice for breast cancer


Ibrance (Palbociclib) has been approved by the US Food and Drug Administration (FDA) in 3 strengths of 75 mg, 100 mg and 125 mg since 2015. To date, the drug has been approved in 97 countries and is chosen by more than 16,000 doctors to treat more than 280,000 breast cancer patients worldwide. Through preliminary clinical evidence, the drug can provide significant improvement over available treatments.
Available on the Vietnamese market from March 2021, Ibrance is a new choice of treating doctors that contributes to optimal results for breast cancer patients. Currently, Vinmec Times City and Vinmec Central Park are the first two hospitals nationwide to distribute Ibrance drugs, helping patients easily access the drug quickly and quickly.

2. What does Ibrance do?

Ibrance is indicated for the treatment of locally advanced or metastatic breast cancer with hormone receptor - HR positive, human epidermal growth factor receptor 2 - HER2 negative, in combination with an inhibitory drug. aromatase or fulvestrant in women who have received prior hormone therapy.
Accordingly, Ibrance has been shown to improve progression-free survival when combined with endocrine therapy.

3. How to use Ibrance?


The treatment with Ibrance is conducted and supervised by a specialist oncologist.
Recommended dose: Take Ibrance 125 mg, 1 tablet per day for 21 consecutive days followed by 7 days off treatment to form a complete cycle of 28 days.
Patients should swallow the tablet whole, do not chew, crush or open the tablet before swallowing. The drug should be taken with food, preferably with meals and at the same time between days.
Dosage of the drug can be adjusted based on the safety and tolerability of the individual patient.

Người bệnh cần nuốt thuốc Ibrance nguyên viên
Người bệnh cần nuốt thuốc Ibrance nguyên viên

4. Unwanted effects when taking Ibrance


The most common adverse reactions with drug use include decreased neutrophil count, decreased white blood cell count, infection, fatigue, nausea, stomatitis, anemia, hair loss, and diarrhea. ..
It is necessary to notify the doctor if you experience any unusual symptoms while taking the drug.

5. Notes when using Ibrance


If the patient vomits or misses a dose, absolutely do not take an additional dose on that day. The next dose is taken as usual.
In addition, patients should note that Ibrance should not be used with grapefruit juice or grapefruit juice because doing this may increase unwanted effects of the drug. Consult your Doctor or Pharmacist before using Ibrance with any other medicines.
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