This is an automatically translated article.
The liver plays a role in digesting food and storing energy. When liver cells become cancerous, the liver cannot function properly, leading to harmful and serious effects on the body.
1. Causes of liver cancer
Liver cancer directly causes unknown, the cancer mechanism is due to a disorder in the genetic structure of the cell's nuclear DNA. Many risks can cause a disorder in the gene structure to cause mutations in the gene:
1.1 Cirrhosis Hepatocellular carcinoma is common in patients with cirrhosis. According to Vietnamese statistics, up to 80% of patients have hepatocellular cancer due to cirrhosis, of which the majority are cirrhosis caused by alcohol.
Most hepatocellular carcinomas develop on the background of liver cirrhosis, especially post-hepatitis cirrhosis. The annual incidence of HCC increases with the severity of liver damage: 0.5 - 1% with chronic hepatitis and cirrhosis.
1.2 Hepatitis B Virus Being infected with the hepatitis B virus increases the risk of developing liver cancer up to 100 times. Up to 80% of liver cancer cases in the world, up to 70% of Vietnam have liver cancer caused by hepatitis B virus. In each of the past years, an estimated 0.5% of people who are chronically infected with the hepatitis B virus develop hepatocellular carcinoma.
1.3 Hepatitis C virus Up to 50% of cases of hepatitis C virus infection in the US, up to 7% of cases in Vietnam have hepatitis C virus.
Relationship between hepatitis B virus and C virus for primary primary liver cancer. According to Vietnamese statistics, up to 81% of hepatocellular carcinoma patients appear to have antigens named HbSAg that are positive for HbSAg. According to statistics in the world in 2004, up to 60% of hepatocellular carcinoma rates are related to hepatitis B virus and 25% are related to hepatitis C virus.
1.4 Alcohol Alcohol is an important risk factor for liver cancer. Although alcohol does not directly cause cancer, it has an extremely toxic role, drinking alcohol for many years in a row shows results: cancer in the pharynx, nasopharynx, esophagus, larynx...
Drinking alcohol often, lasting for many years often causes cirrhosis, from which the foundation develops into hepatocellular cancer.
Alcoholism increases the risk of liver cancer. Regular alcohol consumption, beer consumption is a leading cause of cirrhosis, which accounts for 15% of hepatitis C virus cases.
1.5 Other metastatic diseases Iron overload disease, hereditary diseases of tyrosine plasma , a viral infection that causes chronic hepatitis.
1.6 Other causative factors Aflatoxin is caused by molds from peanuts and peas. Oral contraceptives. Androgenic steroids, thorotrast (contrast). Toxins: Carbon tetrachloride, Agent Orange Dioxin, Azo colorants or nitrosamines causing hepatocellular cancer in experiments.
2. People at high risk of liver cancer
Age: The older people are, the more likely they are to cause cancer. Gender: Men are more likely to develop hepatocellular carcinoma than women, with an average of one in two men developing liver cancer. Race and ethnicity: Asians and Pacific Islanders are more susceptible to hepatocellular carcinoma than Europeans. Other medical conditions: People with hepatitis B or hepatitis C have the highest risk of hepatocellular carcinoma. Obese people. People with cirrhosis of the liver. Metabolic diseases such as diabetes mellitus. Drink a lot of alcohol and smoke. Use steroids to increase strength and muscle mass. Long-term exposure to arsenic, aflatoxin, vinyl chloride, and thorium dioxide.
3. Prevention and treatment of hepatocellular cancer
Vaccination against hepatitis B virus is the most important measure. Stay away from toxic, potentially carcinogenic substances such as moldy, contaminated food. Limit alcohol, tobacco, and stimulants. Periodic health check-up every 6 months. Be physically active. A reasonable diet, limiting greasy foods, baked goods, adding fiber in fruits and vegetables. The methods of diagnosis of liver cancer today mainly include ultrasound examination, CT scan, pathology examination and selective hepatic angiography.
Actively go for regular health check-ups to be monitored, screened and screened by experts for liver cancer early, if any signs of the disease are detected, you should go to the medical center as soon as possible. The liver cancer screening and early detection package at Vinmec International General Hospital helps customers screen for liver cancer so that they can have appropriate and timely treatment.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.