Primary hepatocellular carcinoma is cancer arising from the liver cells, the most common of all liver tumors. Hepatocellular carcinoma is the third leading cause of cancer-related death worldwide.

The liver plays a role in food digestion and energy storage. When liver cells become cancerous, the liver cannot function properly, leading to harmful and serious effects on the body.

The liver is the largest solid organ in the human body, lying to the right in the upper half of the abdomen and separated from the rib cage by the diaphragm. The average weight of an adult liver is about 1.2-1.6 kg. The liver performs many physiological functions in the body.