Antivic drug use

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1. What is Antivic?

What is Antivic? Antivic belongs to the group of drugs for pain caused by neurological diseases, with the main ingredient being Pregabalin 75mg. Pregabalin has analgesic and anticonvulsant effects.
Antivic is made in the form of hard capsules and is indicated for use in the following cases:
Treatment of central nervous system pain and peripheral neuropathic pain caused by damaged nerves causing pain lengthen. Treatment of partial seizures may or may not be accompanied by generalized seizures. In combination with other antiepileptic drugs for the adjuvant treatment of epilepsy in cases of uncontrolled disease. Treatment of generalized anxiety disorder.

2. How to use and dose Antivic

Antivic drugs are taken orally, take them with water, can be taken on an empty stomach or full. The average total dose is 150-600mg/day and is divided into 2-3 times a day.
Specific Antivic drug dosage is as follows:
Treatment of neuropathic pain: The initial dose is 150mg/day, divided into 2-3 times a day. The dose may be increased to 300 mg/day within 1 week depending on the patient's response and tolerability. Within the next 1 week, can continue to increase to 600mg/day. Supportive treatment of partial seizures: The initial dose is 150mg/day, after 7 days if the patient has a response, increase the dose of Antivic to 300mg/day, then continue to increase to 600mg/day. Treatment of generalized anxiety disorder: The total dose is in the range of 150-600mg/day, divided into 2-3 times a day. For appropriate dosing, the need for treatment should be assessed regularly. The initial dose may be 150 mg/day. After 1 week, depending on the patient's tolerability and response, the dose of Antivic should be adjusted to 300mg/day. After the next 1 week, the dose can be increased to 450 mg/day and then can be further increased to a maximum of 600 mg/day. Information on overdosage of Antivic is limited, with doses up to 800mg, no clinical adverse effects have been reported. Therefore, to date, there is no specific antidote for overdose.
When using an overdose of Antivic, the patient should be gastric lavage, induce vomiting, maintain the airway if indicated. In addition, it is necessary to apply symptomatic and supportive measures. If indicated, hemodialysis can be performed to remove the drug within 4 hours of dosing.

3. Side effects of Antivic drugs

Antivic drugs can cause some unwanted side effects with the frequency of occurrence as follows:
Common: Dizziness, headache, drowsiness, ataxia; double vision, blurred vision; peripheral edema, dry mouth, weight gain; joint pain, pain in the limbs, back pain, cramps , muscle tremors, cervical spasms; infection. Uncommon: Antivic rarely causes side effects such as dizziness, headache, fatigue, memory loss or loss, confusion, neuritis, attention disorders, language disorders, loss of coordination , disorientation, anxiety, stupor, depression, agitation, euphoria, depersonalization, abnormal thinking, abnormal sensations, fever, lethargy, lethargy, increased muscle tone. Antivic drugs rarely cause vision loss, conjunctivitis, visual disturbances, nystagmus; hearing loss, sinusitis, pharyngitis, laryngitis, bronchitis, shortness of breath; edema, chest pain, itching, bruising, facial edema; hypoglycemia, fluid retention; abdominal pain, flatulence, appetite, vomiting, constipation, gastroenteritis. Antivic drugs rarely cause urinary incontinence, polyuria, sexual impairment; thrombocytopenia, arthralgia, back pain, muscle weakness, myoclonus, muscle spasms, myasthenia gravis, myalgia, balance disorder, abnormal walking, cramps, paresthesia, increased CPK concentration; flu syndrome, allergic reactions. If you see any strange symptoms after taking Antivic, the patient should stop taking the drug and report it to the doctor immediately or go to a medical facility soon for a health check.
In some cases, side effects of blurred vision can go away on their own while the patient is still taking the drug, very rarely stopping the drug. An ophthalmologist should be examined if the patient has visual disturbances.
In particular, the patient must stop taking Antivic immediately if there is myopathy or the serum CPK level is 3 times higher than normal. People with heart disease, if they have symptoms of peripheral edema and weight gain, need to stop taking the drug immediately.

4. Some notes when using Antivic drugs

Some notes when using Antivic drugs are as follows:
Do not use Antivic in people with hypersensitivity to the ingredients of the drug. Do not arbitrarily buy and use Antivic drugs without the opinion or prescription of a doctor. If you notice any suspicious signs of an allergic reaction such as a rash on the skin, swelling of the face, mouth, tongue and throat, the patient should immediately notify the doctor. Elderly people need to be careful when taking Antivic, because the drug can increase the risk of falling because the drug causes side effects such as drowsiness, dizziness. If there are any signs related to vision such as blurred vision after taking Antivic, the patient should immediately report to the treating doctor or visit an ophthalmologist. People with diabetes may need to change their diabetes medication if taking Antivic causes them to gain weight. Patients should inform their doctor about a history of heart disease (if any) before taking Antivic, because the drug can cause heart failure, especially in elderly patients with cardiovascular disease. Tell the doctor if the patient has low urine output after taking the medicine. During the course of taking Antivic, patients should be closely monitored and monitored for symptoms of depression, insomnia, anxiety, abnormal behavior such as opposition, aggression, aggression or suicidal ideation. Antivic drugs in particular and anticonvulsants in general can increase the risk of this side effect. Concomitant use of Antivic with certain other drugs such as pain relievers can affect the digestive system and cause constipation, paralytic ileus or intestinal obstruction. At that time, the patient should immediately notify the doctor. Tell your doctor about your history of alcoholism or drug abuse before taking Antivic. While taking the drug, the patient should not exceed the prescribed dose. After taking the drug or stopping taking it for a short time, if the patient has a seizure, the patient should immediately notify the doctor. Patients should inform their doctor about a history of serious illness (if any, including kidney disease, liver disease) before taking Antivic, because the drug can cause brain function impairment. Elderly patients or have respiratory disorders, nervous system disorders, kidney failure should notify the doctor when having difficulty breathing or shallow breathing after taking Antivic so that the doctor can guide the use of the drug. Limit the activity of driving or operating, operating machinery while taking Antivic because the drug can cause drowsiness, dizziness, decreased concentration. Pregnant women should only use the drug after weighing the benefits and risks for the mother and the fetus, because the research information on this group of subjects is limited. Women of childbearing age must use contraception if taking Antivic. Breastfeeding women who want to take the drug must stop breastfeeding. It is necessary to examine and check the patient's hypersensitivity history before using Antivic, because the drug can cause angioedema, and to prepare emergency measures or means if the patient has angioedema. If the drug is to be discontinued, the dose should be reduced gradually over a minimum of one week, avoiding abrupt discontinuation. The use of Antivic is to relieve pain in patients with central or peripheral neuropathic pain and anticonvulsant in patients with partial epilepsy. Antivic can be combined with other antiepileptic drugs to support the treatment of epilepsy.
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