This is an automatically translated article.
Cododamed drug has the main ingredient is Pregabalin. The drug is indicated in the treatment of anxiety disorders, pain relief, partial seizures. What is Cododamed drug, how to use it, let's find out the use of Cododamed through the article below.
1. What is Cododamed 75mg?
Manufacturer: Pharmaceutical Works Adamed Pharma Joint Stock Company.
Packing: Box of 4 blisters x 14 tablets.
Dosage form: Hard capsule.
Ingredients:
Pregabalin 75 mg. Excipients 1 capsule.
2. Uses of Cododamed
The effect of Pregabalin in the formula
Pregabalin has a similar structure to Gamma Butyric Acid (GABA). Binding to the subunit in the calcium line in the nervous system, replacing [3H] - Gabapentin helps the drug to have analgesic and anticonvulsant effects. This active substance does not act on the receptors or mechanism of action like other antiepileptic drugs. It is used to treat neuropathic conditions, fibromyalgia, and to treat onset seizures. It can be used alone or in combination with other drugs. 2.1 Indications The drug is used in the following cases:
Central and peripheral neuropathic pain. Generalized anxiety disorder. Adjunctive treatment of partial seizures (including secondary generalization). 2.2 How to use - Dosage How to use:
Take the tablet whole with an appropriate amount of water. Do not break, chew or crush tablets. Time of use:
+ Drink 2 times a day: morning, evening.
+ Drink 3 times / day: Morning, noon, evening.
+ The use of the drug does not depend on the meal.
Should be taken at a fixed time to ensure the effectiveness of the drug.
Dosage:
As prescribed by the doctor. Refer to the following dose:
- Take 150 mg/day, 2-3 times/day at the therapeutic dose. Increase dose by 300 mg/day after 3-7 days, to a maximum of 600 mg in the following week.
- When stopping the drug, it is necessary to gradually reduce the dose for at least 1 week.
- Kidney failure, the elderly: Drink 1-3 times/day. Dose based on renal creatinine clearance:
| Độ thanh thải Creatinin thận CC (ml/phút) | Liều dùng |
|---|---|
| < 15 | 25 mg/ngày, tối đa 75 mg/ngày |
| 5 ≤ CC < 30 | 25 - 50 mg/ngày, không quá 150 mg/ngày |
| 30 ≤ CC < 60 | Khởi đầu 75mg/ngày, tối đa 300 mg/ngày |
| CC ≥ 60 | 150 mg/ngày, tăng liều cao nhất 600 mg/ngày |
2.3 Missed dose, overdose and management Missed dose :
Make up if it is still far from the time of next dose. If it is almost time for your next dose, continue taking it as usual, do not take a double dose.
Overdose:
Symptoms: Confusion, restlessness, agitation, drowsiness, coma may occur.
Treatment: If unusual symptoms appear, contact your doctor or pharmacist immediately. Hemodialysis can remove the drug. Coordinating symptomatic treatment to support recovery.
3. Effects of the drug Cododamed
During treatment, some adverse reactions may occur:
Very common: Dizziness, drowsiness, headache.
Common : Upper respiratory tract infection, appetite, irritability, decreased libido, insomnia, confusion, loss of balance, memory impairment, paresthesia, visual impairment, double vision, vomiting, constipation, diarrhea diarrhea, bloating, cramps, back pain, joint pain, erectile dysfunction, edema.
Uncommon: Neutropenia, hypersensitivity, anorexia, hallucinations, depersonalization, syncope, myoclonic jerks, decreased reflexes, visual disturbances, dry eyes, increased visual acuity, tachycardia, atrial block 1st degree ventricle, abnormal blood pressure, difficulty breathing, nosebleeds, rash, joint swelling, dysuria, pain, fever, increased Creatin Phosphokinase, hypokalemia,...
Rare: Allergies, loss of reflexes conditions, seizures, dysosmia, keratitis, fluctuating vision, QT interval prolongation, pneumonia, ascites, pancreatitis, Stevens-Johnson syndrome, rhabdomyolysis, renal failure, amenorrhea, breast enlarged, leukopenia.
Immediately report to the doctor any side effects encountered for timely treatment.
4. Note when using the drug Cododamed
Contraindications:
Not to be used in case of hypersensitivity to any ingredient of Cododamed 75mg.
Note:
Use in pregnant women and lactating mothers
Pregnant women: Animal tests have shown teratogenic potential, however there are no adequate human evaluations . Weigh the benefits and risks, consult your doctor before taking.
Breastfeeding women: The drug can be excreted in breast milk, the effects of the drug on the newborn are not well understood. Breastfeeding should be discontinued while taking the drug.
People who drive and operate machines
The drug can cause dizziness, drowsiness, affecting the ability to drive and use machines. Be careful when participating in activities that require alertness and concentration.
Other notes:
Read the instructions carefully before using. There is not enough information on the safety and effectiveness for children under 18 years old, do not use the drug for these subjects. Do not discontinue current antiepileptic drugs as Pregabalin is used only as adjunctive therapy. Withdrawal symptoms may occur at the end of treatment, and this effect is usually dose related. Use caution when treating people with diabetes, the elderly, cardiovascular disease, spinal cord injury, encephalopathy and some other factors that increase the risk of side effects. People with Galactose intolerance, Lactase-converting enzyme deficiency, and poor absorption of Glucose - Galactose should not use the drug because it contains Lactose. There have been reports of behavioral disorders, suicidal thoughts during treatment. Patients need to be monitored for these signs, consulted to seek medical support in time.
5. Drug interactions
To date, only one notable interaction has been recorded: Pregabalin enhances the effect of central analgesics (Oxycodone, Ethanol, Lorazepam). There have been post-marketing reports of respiratory failure or coma during combination therapy. Inform the doctor about the drugs and functional foods being used for effective treatment. Storage
Store in a dry place, the temperature is below 30 degrees Celsius, protect from light. Keep out of reach of children.
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