Adverse drug interactions of Progermila

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Progermila is a drug commonly used to treat and prevent intestinal microflora disorders, endogenous vitamin malabsorption. To better understand the use of Progermila what is it? What are the harmful interactions of the drug Progermila? What is the correct way to drink? What points should you pay attention to when using? The following article will help you better understand the drug Progermila.

1. What is Progermila?


Progermila is a gastrointestinal drug - Drug Visa Number / Registration Number / ID: QLSP-903-15 is manufactured by CPC1 Pharmaceutical Joint Stock Company Hanoi - VIETNAM.
1.1. Dosage form: Oral suspension
1.2. Ingredients Bacillus Clausii 2 x 10^9 CFU/5ml
Distilled water just enough 5ml
1.3. Pharmacology and mechanism Anti-intestinal dysbacteriosis is due to the presence of anti-diarrheal bacteria and is therefore used to treat imbalances in the intestinal flora.
Mechanism of action:
When taking Bacillus clausii spores, thanks to their strong antagonism against chemical and physical agents, the drug passes through the gastric acid barrier intact, into the gastrointestinal tract. and transformed into metabolically active vegetative cells.
Thanks to the effect of Bacillus clausii, Bacillus clausii when taken orally contributes to the restoration of the intestinal microflora that has been changed due to many sources. Furthermore, because Bacillus clausii has the ability to produce some vitamins, especially B vitamins, it also contributes to vitamin deficiencies caused by the use of antibiotics and chemotherapy.
Bacillus clausii can induce nonspecific antibody production and has a detoxifying effect, which is closely related to the metabolic effects of Bacillus clausii. In addition, the high level of antibiotic resistance of bacterial strains through artificial selection, providing a therapeutic basis for the prevention of alteration or to re-establish the balance of the intestinal flora, occurs. occurs after the selective action of antibiotics, especially broad-spectrum antibiotics.
Due to its resistance to antibiotics, Bacillus clausii can be taken between two doses of antibiotics. The antibiotics mentioned include: penicillins, cephalosporins, tetracyclines, macrolides, aminoglycosides, novobiocin, chloramphenicol, thiamphenicol, lincomycin, isoniazid, cycloserine, rifampicin, nalidixic acid and pipemidic acid.
1.4. Pharmacokinetics Kinetics of absorption, distribution, metabolism and elimination of drugs to know how to choose the route of drug delivery (oral, intramuscular, intravenous injection, ...), the number of times of drug administration per day. , drug dosage depends on each case (age, disease state, physiological state...)

2. Uses of the drug Progermila


Indications Progermila 20 ampoules:
Treatment and prevention of intestinal microflora disorders and pathological endogenous vitamin malabsorption Adjuvant therapy to restore intestinal microflora affected when taking drugs antibiotics or chemotherapy Acute and chronic digestive disorders in children such as dyspepsia, abdominal distension, flatulence, raw stools, constipation, diarrhea, etc.

3. Adverse drug interactions of Progermila


So far there have been no records related to the use of this probiotic causing unwanted effects on children or any other subjects

4. Drug interactions


4.1. What other medicines does Progermila interact with? It is important to remember that drug interactions with other drugs are often quite complicated due to the influence of many ingredients in the drug. Studies or recommendations usually only state common interactions with use. Therefore, do not arbitrarily apply information about Progermila drug interactions if you are not a researcher, doctor or medical person.
4.2. Drug interactions Progermila with food, drink Consider using the drug together with alcohol, tobacco, alcoholic or fermented beverages. Factors that can change the composition of the drug. See details in the leaflet or consult your doctor or pharmacist for more details.

5. How to use Progermila effectively?


5.1. How to give probiotics Progermila to children? This suspension is also used orally, give it to your baby to drink directly from the tube, because this yeast is odorless and tasteless, so it is easy to drink and suitable for babies First, please separate the ampoule from the blister, check carefully, then shake well, screw the cap. Remember to shake well before giving it to your baby. In addition, you can also dilute it with water, milk, ... and then give it to your baby to use. However, according to the advice of skin experts, although bacillus clausii spores are present in Progermila Can withstand high temperatures but you still should not mix it with hot food After a period of storage, sometimes you see a white bite on the bottom of the tube, don't worry: it's not because of the medicine. 5.2. Dosage Dosage for adults: take 1-2 ampoules 1-2 times a day Dose for children: take 1 tube x 1-2 times a day 5.3. Overdose, missed dose and management What to do in case of overdose Progermila
Prescription drugs require a prescription from a doctor or pharmacist. Over-the-counter medicines require a leaflet from the manufacturer. Carefully read and follow the exact dose indicated on the prescription or medication leaflet. When taking an overdose of Progermila, you need to stop taking it, immediately notify your doctor or pharmacist when there are abnormal symptoms
Note to handle in case of overdose
Unusual manifestations of overdose need to notify the doctor or health care provider. In case of overdose Progermila has symptoms that require emergency: Call 911 immediately for guidance and help. Family members should bring medical records, all prescriptions/vials that have been used and are being used so that doctors can quickly diagnose and treat
What to do if a dose of Progermila is forgotten
Usually medicines can Take 1-2 hours longer than prescribed in the prescription. Unless there is a strict rule about the time of use, the medicine can be taken a few hours after forgetting. However, if the time is too far from the time you need to drink, you should not take it, which can be dangerous for the body. It is necessary to strictly adhere to or consult a doctor before making a decision.

6. Precautions and notes when using Progermila


6.1. Notes and cautions before taking Progermila The subjects that need to be noted before taking Progermila: the elderly, pregnant women, lactating women, children under 15 years old, people with liver failure, kidney failure, people who are allergic to any substance in the drug's ingredients... Or subjects with myasthenia gravis, hepatic coma, stomach ulcers.
6.2. Note during pregnancy Can pregnant women take Progermila?
Consider and consult your doctor or pharmacist before taking medicine. Even tested drugs still have risks when used.
6.3. Note the breastfeeding period Mothers need to carefully weigh the benefits and risks for mother and baby. Do not arbitrarily use the drug without carefully reading the instructions for use and instructions of the doctor to protect the mother and baby

7. Preservation of Progermila


Store in a cool, dry place, away from light, at a temperature below 30 degrees C
Read carefully the instructions for storing the drug on the package and the instruction sheet for Progermila. Check the expiry date of the medicine. When not in use, the drug should be collected and disposed of according to the instructions of the manufacturer or the person in charge of medicine. Conventional drugs are stored at room temperature, avoiding direct sunlight or high temperature, which can convert the ingredients in the drug.

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