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Drotaverine is used for the relief of menstrual pain, kidney stones, gallstones and gastrointestinal tract. Drotaverine is not recommended for use in children under 1 year of age and should be considered with pregnant women because of its effects on pregnancy.
1. What does Drotaverin do?
Drotaverine is an antispasmodic drug similar in structure to Papaverine. This is a phosphodiesterase 4 inhibitor with no anticholinergic properties. In animal models, Drotaverine has been shown to have a dose-dependent analgesic effect. According to one small study, Drotaverine was largely eliminated non-renal. As such, this ingredient has been used as an effective drug used to treat spasms or convulsions of smooth muscles in the stomach and heart. It is also used to relieve pain caused by irritable bowel syndrome , headaches , menstrual cycles , and to relieve cervical spasms during labor .
The uses of Drotaverine have been documented as an important treatment for pain relief. Specifically, when taking one tablet of Drotaverine 40mg, the patient will be relieved of pain caused by irritable bowel syndrome, headache, dysmenorrhea and cervical spasms during childbirth. In addition, Drotaverine also cures stomach pain, chest pain, gallstones, renal colic and some other diseases.
2. How to take Drotaverine
Drotaverine can be taken with or after meals as an oral tablet 3 times a day. Dosage in adults can be 40-80 mg, so manufacturers present it as Drotaverine 40mg, although this dose will vary with each individual's medical condition.
Children 1 to 6 years of age can be given an antispasmodic in a strength of 20 mg 3-4 times a day if taken orally. In children over 6 years of age, the dose is usually increased to 40 mg. This therapy helps restore cyclic AMP equilibrium to calcium ions at the site of contraction by blocking the enzyme phosphodiesterase IV in smooth muscle.
For the missed dose, there is absolutely no harm to the body if 1 or 2 doses of Drotaverine are accidentally missed. Although there is no problem with the missed dose, if it is not taken on time, it will not have the desired effect. Furthermore, sudden chemical changes in the body can occur if a dose is missed. So, if a dose is missed, your doctor may recommend taking a supplement as soon as possible.
On the contrary, in case of overdose, the patient should consult a doctor immediately. Restlessness, confusion, and dizziness are typical symptoms of overdose. Severity of symptoms may warrant consideration of the possibility of gastric lavage.
Drotaverine 40mg được chỉ định cho việc điều trị giảm đau bụng kinh, sỏi thận, sỏi mật và dạ dày-ruột
3. Side effects when taking Drotaverine
Some common and serious side effects of Drotaverine are:
Nausea; Vomiting; Dry mouth ; Changes in the rate of bowel movements; Dizzy; Headache; Shortness of breath; Skin allergies; Swelling of the face, lips, eyelids and tongue; Hypotension; Dizzy; Constipation; Sleep disorders ; Skin inflammation.
4. Drotaverine use warning for some special health conditions
4.1. Liver disease and Drotaverine Drotaverine 40 mg or lower should be used with caution in patients with impaired liver function. Appropriate dosage adjustment and safety monitoring are recommended if hepatic impairment becomes severe.
4.2. Drotaverine and pregnancy Pregnant women should not take Drotaverine unless absolutely necessary and the benefits outweigh the risks. Accordingly, before taking this medication, talk to your doctor. However, when indicated for obstetric purposes, drotaverine is a drug commonly used in late pregnancy. A prospective randomized study of 200 women in spontaneous labor was performed in 100 women who received 40 mg of drotaverine hydrochloride intravenously when the cervix was dilated > or = 3 cm, the remaining 100 women were included as controls. proof. The effect of the drug on the progression and outcome of labor has been documented as drotaverine is highly effective in reducing the duration of active labor by accelerating cervical dilation. Therefore, drotaverine works to reduce the rate of bleeding after trauma by reducing the rate of cervical tear, making it a safe drug for the mother as well as for the baby.
4.3. Drotaverine for breastfeeding women If you are breastfeeding, you should not take Drotaverine because the potential for adverse effects on the baby is very high. Consult your doctor about the possible dangers of using this medicine.
In a nutshell, Drotaverine is an antispasmodic drug used to relax smooth muscles such as the stomach and heart muscles. Knowing what Drotaverin does and using it properly will help soothe excessive bowel movements, headaches, menstrual pain, duodenal ulcers and reduce cervical spasms during childbirth. Drotaverine is also used to treat biliary dyskinesia, prostatic hypertrophy, and other vasomotor diseases, thereby improving function and quality of life for patients.
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