What diseases does Topamax treat?

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What disease does topamax treat? What should be noted when using drugs to be safe and effective for health?

1. Overview of the outstanding features of Topamax drug

Topamax, also known as topiramate, is FDA approved for use as an antiepileptic or anticonvulsant. The age limit for using this medicine is also wide enough that adults and children over 2 years old who have a doctor's prescription can use the drug.
In addition, when using topamax can prevent migraine symptoms in adults and adolescents over 12 years of age. But medication is only able to prevent pain and reduce the amount of pain. According to many studies, the results show that the pain relief is only temporary, in fact the root cause is not addressed.
Also, a few uses of topamax are still being researched. Therefore, some of the benefits of the drug have yet to be found. You can also use them to treat problems not listed in the indications. But it's quite dangerous, so a doctor's advice and supervision is required.

2. Uses of topamax

What are the uses of Topamax? According to the indicated instructions, the drug topamax 25mg sold in pharmacies can be used for cases such as:
Treatment prescribed by a doctor for children over 6 years old and adults. The disease indicated for treatment may be with partial epilepsy or without symptoms of secondary generalized epilepsy. In some cases, this may be indicated if the seizure is leading to tonicity or primary complete convulsion. Use combination therapy for children over 2 years of age and adults with partial onset seizures. Some cases may or may not be accompanied by secondary complete seizures. It can also be used for seizures that result in complete seizures or secondary spasticity. In the treatment of epilepsy, such seizures are diagnosed in association with Lennox Gastaut syndrome. Migraine headaches in adults can be relieved with use. Therefore, when treating, some doctors will carefully evaluate the priority of the best approach. In case of force majeure, topamax can be used for treatment. Topamax is classified as a monosaccharide capable of substituting for sulphonamides. The charged particles will act over and over because of the suppression of the neutron, which is inhibited by topamax. According to the time-dependent trend, the impact on sodium will vary from state to state.
Topamax has the ability to increase the frequency of GABA receptors activated by y-aminobutyrate. At the same time, it also has the ability to create a stream of chloride ions that penetrate neurons from GABA. This is the activity of the substance capable of transmitting to the inhibitory nerve.
The body's ability to absorb Topamax is quite fast and effective. They do not have the ability to strongly induce enzymes or metabolize drugs without controlling the food intake each day. Therefore, it is not necessary to perform a test to determine the concentration of topiramate in the blood plasma.

The amount of topiramate bound to plasma proteins may be in the range of 13 - 17%. This is the mean volume of distribution equivalent to 0.08 - 0.55 l/kg topiramate when the indicated dose is at 100 - 1200 mg.
The amount of topiramate after taking into the body is not metabolized too much. Usually about 20% metabolized in healthy body. For patients who are prescribed an additional drug for epilepsy, the metabolic rate increases by 50%. This is because antiepileptic drugs can increase sensitivity to drug-metabolizing enzymes.
There are 6 groups of metabolites that can be directed to support topiramate's rapid metabolism. Metabolites are formed through daily bodily activities such as: hydrogenation, hydrolysis, sequestration of conjugated glucose, qualitatively by plasma, urine and faeces excretion.
For the human body, the kidney is the organ that performs the function of eliminating topiramate metabolism. This pathway is the major route, in addition to plasma clearance occurring. When conducting plasma clearance reached 20 - 30 ml/min for those already taking topamax.

3. Warnings to pay attention to before taking topamax drug treatment

3.1. Danger warning to be aware of According to some studies, topamax may inadvertently become the cause of vision problems. This problem is more serious than it is difficult to treat quickly and there is a risk of not being cured. Therefore, you need to monitor your health regularly and notify your doctor early if you find a sudden vision loss problem.
Based on experimental observations, topamax may affect perspiration. For children, when the sweat glands are not working properly, they will lead to a life-threatening increase in body temperature. When the body temperature is high, it will be able to make the body lose water, reduce electrolytes, affect the resistance. If you find it difficult to sweat along with dry hot skin and high fever, please notify your doctor soon for timely monitoring and treatment.
Negative psychological developments often occur with psychological patients. People with epilepsy often behave abnormally, but not many tend to act negatively. However, after using antiepileptic drugs, the risk of suicide may occur.
Abnormal changes in psychology are a warning of bad risks and out of control behavior. If during the course of taking the drug you feel abnormal psychological developments, please notify your doctor for early detection monitoring. While taking this medication, be sure to take it at regular intervals and do not change or stop it suddenly, causing seizures to increase.
3.2 Warning before using medicine to treat Topamax also known as topiramate an ingredient that can cause allergies when used. Therefore, you need to tell your doctor not to use them if your body is allergic. At the same time, it should not be used if the existing medical condition is high blood acid and people with diabetes have prescribed metformin. During treatment, you should tell your doctor if you have one of the following diseases so that the doctor can reconsider how to use topamax effectively and safely:
Diseases affecting vision or diseases causing glaucoma Pressure People who have diabetes or have high blood acid levels Are undergoing dialysis, are treated for kidney problems or have kidney stones Have respiratory problems or lung problems People is being treated for negative psychology, may be in a weak state. Patients at risk for depression or autism should consider eating disorders Illnesses resulting from impaired liver function Osteoporosis symptoms or findings, osteomalacia Growth problems have an unusual disorder Diarrhea appears

People with high blood acid levels are diagnosed if using topamax will push the acid level higher. At that time, the body will be heavily affected in the hard part, making bones weak and at risk of causing kidney stones. For children in the developmental stage, using topamax is at risk of growth disorders, and the fetus received through the mother will be seriously affected. To be safe, you need to conduct blood tests and check your pregnancy status to consider using the drug.
When using anticonvulsant drugs, the patient will have a feeling of being ignored. For pregnant women, doctors will regularly monitor and check the growth of the fetus periodically if there is an indication to use topamax. The symptoms may appear early but are not clear, so the family should pay attention to be alert when the patient has abnormalities in order to promptly treat and come up with a reasonable plan.
Women who are pregnant, if using topamax, can have problems with birth defects such as cleft palate, cleft lip, some of which can lead to organ abnormalities or abnormal development. . In addition, anticonvulsants such as topamax should not be used during pregnancy because convulsions are dangerous for both the child and the mother. If you are pregnant, tell your doctor for advice and support.
Although pregnant women need to be treated with topamax when they have a seizure problem, it shows that the drug's effectiveness only affects the seizure problem and has no other side effects, but it should not be subjective. Your doctor will give you advice and consider other safer medications. Therefore, it is not possible to arbitrarily use or stop using topamax without consulting a doctor.
In addition, the effectiveness of oral contraceptives may be reduced if topamax is used together. If you need an effective birth control while taking topamax, choose a non-hormonal method to be sure. For those who are nursing and breast-feeding should avoid using topamax without the permission of the doctor.

4. Instructions for using the drug topamax

The best way to use topamax is when advised and prescribed by a doctor. Dosage instructions and dosage should be discussed with your doctor first. While using, it is necessary to adhere to the dosage and avoid abrupt stop without a new indication.
The drug can be taken with or without food. This depends on the individual situation. But absolutely do not chew or crush the topamax tablet. You need to swallow the capsule whole.
Each dose of topiramate is tailored to the child's weight. This will ensure that the dose is balanced for each child as their weight changes. You may experience problems such as kidney stones or electrolyte imbalance while taking this medicine. Therefore, drink plenty of water each time you take the medicine.
During the course of using topamax, conducting regular blood tests is a way to monitor health safety. If you have surgery, tell your doctor if you have had previous treatment with topamax. Antiepileptic or anticonvulsant drugs can affect the results of surgery, so please notify the doctor as soon as possible.
During the time you are prescribed topamax, absolutely do not stop using the drug on your own even if you feel your body is stable. Discontinuing the drug completely can cause seizures that come on suddenly. If you are taking medication and your convulsions don't go away and get worse, tell your doctor right away.
Topamax medicine to ensure its use needs to be preserved very well. The temperature environment needs to be cool, hidden, and not high-frequency light generating high heat. At the same time, each dose of medicine is stored in the box and you need to make sure it is tightly closed after each use.
If you miss a dose, you can take the medicine within 6 hours from the last time you need to take it. Then you can change the usage schedule to balance. If the number of missed doses is too much, you need to notify your doctor for advice and help promptly.
When using the drug overdose, you may experience problems such as: drowsiness, psychological phobia, impaired speech reflexes, convulsions or fainting. Pay attention to the symptoms to detect and report to your doctor. Alcohol should not be used with topamax because they can make seizures worse.
The keto diet often increases fat intake and reduces protein and carbohydrates which can put you at an increased risk of kidney stones. So you need to pay attention to your activities and eating if you are using topamax for treatment. In addition, you need to avoid strenuous or dangerous activities such as climbing, swimming. The disease can appear suddenly when you are active and cause serious effects.

5. Side effects and filling to avoid when using topamax

Side effects when using the drug topamax treatment can be caused by allergies or serious skin reactions. Most of the time, when side effects occur, the patient will be abnormal with fever, difficulty breathing or swelling. If you experience any of the following symptoms, please notify your doctor immediately for assistance:
Skin rash appears Disturbance of vision causing eye pain, redness or impaired vision Difficulty keeping focus, impaired memory loss or cognitive disturbances Elevated body temperature with a feeling of dryness on the skin and decreased perspiration Occurrence of severe pain in the back or side or difficulty urinating Unstable heartbeat, fatigue Fatigue with loss of appetite or shortness of breath Frequent fainting with fatigue and vomiting with no apparent cause These symptoms are also common side effects that may be encountered during the treatment of Topamax. This is not all but the side effects of the drug, so you need to monitor if you find your body is not good or your condition does not improve, you should report it soon to get help from your doctor.

6. Drugs that are likely to interact with the ingredients that make topamax

If taking topamax treatment with other drugs, there is a possibility that you will have a craving for sleep and sleep more. In such a situation, it is necessary to inform the doctor immediately to avoid the use of sleeping pills, pain relievers or muscle relaxants. More importantly, drugs to treat mental illness should be consulted by a doctor carefully before being used with topamax to treat illness.
If you are prescribed topamax, tell your doctor what drugs you are taking. For the following drugs you should stop if prescribed topamax to avoid reducing their effectiveness: birth control pills, glaucoma medications, valproic acid.....
There are many drugs that have the risk of interacting with topmax. Therefore, you need to consult your doctor carefully as well as inform the medications you are taking and your personal medical history. When your doctor is well informed, he or she will be able to make the best decision that works best for you.
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