This is an automatically translated article.
There are many methods of birth control with varying degrees of effectiveness, the most effective of which is considered to be the oral contraceptive pill. An effective birth control product that is widely used by women today is a combination of Ethinyl Estradiol and Desogestrel called Regulon.
1. What is Regulon?
Regulon is a product of Gedeon Richter PLc Company, the composition includes 2 active ingredients, Ethinyl Estradiol 0.03mg and Desogestrel 0.15mg.
Regulon is used daily for the main purpose of contraception, each pack includes 21 pills and each box has 1 blister or 3 blisters. Regulon prepares white, round, biconvex, film-coated tablets, 6mm in diameter, imprinted with the letter P8 on one side and the letter RG on the other side.
2. Indications and contraindications of the drug Regulon
Regulon is indicated for the purpose of preventing pregnancy. However, this product is contraindicated for use in the following cases:
People with confirmed or suspected pregnancy; Patients with moderate to severe hypertension; Hyperlipoproteinemia; Presence or history of arterial thrombosis (such as myocardial infarction or cerebrovascular accident); People with risk factors for the formation of arteriovenous thrombosis; Personal or family history of thromboembolic events; People with vascular complications due to diabetes; Patients with or with a history of severe liver disease, cholestatic jaundice or hepatitis, history of gestational jaundice, steroid-induced jaundice, Rotor syndrome and Dubin-Johnson syndrome, hepatocellular tumors and disorders porphyrin metabolism; Gallstones; Confirmed or suspected estrogen-dependent tumor, endometrial hyperplasia, vaginal bleeding of unknown etiology; History of or current systemic lupus erythematosus ; History of pregnancy or previous steroid use with severe itching, genital herpes infection, otosclerosis; Hypersensitivity to any of the ingredients in Regulon.
3. Instructions for using the drug Regulon
Users should start taking Regulon on the first day of their menstrual cycle, maintain taking 1 tablet of Regulon daily for 21 days (preferably at the same time each day). After that is 7 consecutive days without taking the drug and usually during this time the user will have a period.
Continue the course with the same new Regulon pack, starting on the 8th day (after 7 days of not taking the previous pack) even if the user is still menstruating. Note that users must continuously repeat the above regimen until there is still a need for contraception.
3.1. Taking Regulon for the first time People who are taking Regulon for the first time should start taking the first pill on the first day of their menstrual cycle. In some cases, it is possible to start taking Regulon from day 2 to day 5 of the menstrual cycle, but this must be combined with a safe method of birth control during the first 7 days of the cycle. After the 5th day of the menstrual cycle, users should wait until the next cycle to start taking Regulon according to the instructions above.
3.2. Postpartum Regulon Use If the mother is not breastfeeding, she can start taking Regulon on the 21st day postpartum and no additional birth control is needed.
If you have had sex after giving birth, you should postpone taking Regulon until the first menstrual period. If Regulon is started more than 21 days after giving birth, the user needs to use another method of birth control for the first 7 days.
3.3. Using Regulon after a miscarriage or abortion After a miscarriage or abortion, users can start taking Regulon right away and do not need to apply other methods of contraception.
3.4. Switching from another birth control pill to Regulon In case of changing from a 21 or 22 day birth control pill to Regulon: The user must finish all the pills of the old pack, then continue taking the first pill of the pack. Regulon , which means there is no gap between these two types of birth control pills. You may not need to use another method of birth control then.
In case of changing from a 28-day birth control pill to a Regulon pill: The user takes the first pill of the Regulon pack after taking all the pills of the old birth control pill, there is no interval between the two pills. The patient does not need to wait until the start of a new menstrual period and does not need to use another method of contraception in this case.
In case of switching from a progesterone-only pill to a Regulon pill: The user starts taking Regulon on the first day of menstruation and does not need to use any other methods of birth control. If the user is not menstruating on a progesterone-only pill, they can start taking Regulon on any day of their cycle, but must use another method of birth control for the first 7 days.
3.5. Regulon Overdose and Treatment No serious adverse effects have been observed with Regulon overdosage, and therefore no treatment is required. However, if the user takes an overdose of Regulon when necessary, it is possible to wash the stomach and treat symptoms because there is no specific antidote.
If the user experiences vomiting and diarrhea after taking Regulon, the absorption of the drug may be impaired. If this condition clears up within 12 hours, the user takes another Regulon tablet from the backup pack, then takes the rest as directed. If vomiting persists for more than 12 hours, the user must apply another form of birth control for the duration of the gastrointestinal disturbance and maintain for at least 7 days thereafter.
3.6. Missed dose of Regulon and what to do If you forget to take Regulon at the prescribed time, the user must take a supplement within 12 hours, then return to the usual dosing schedule. In this case, there is no need to use additional methods of contraception.
If the user forgets to take one or more pills after more than 12 hours, the contraceptive effect of Regulon may be reduced. Users should take the last forgotten Regulon tablet, even if they have to take 2 pills in a day, and then return to their usual dosing schedule. This case requires the user to apply another method of birth control for the next 7 days.
4. Side effects of the drug Regulon
When using Regulon oral contraceptives, users are at risk of some unwanted effects:
Rare events related to Regulon use and the risk of venous thromboembolism, including infarction myocardial infarction, stroke, deep vein thrombosis or pulmonary embolism; Very rarely, Regulon can trigger a response in systemic lupus erythematosus; Vaginal bleeding without menstrual cycle, amenorrhea after taking Regulon drug; Regulon may alter cervical secretions, increase the size of fibroids, or worsen endometriosis; Regulon increases the risk of vaginal yeast infections (such as Candida); Tightness, pain, increase in size, or unusual discharge in the breast; Erythema nodosum, rash or pigmentation of the face; headache, migraine, personality changes, or depression; fluid retention causing edema, weight change, or impaired glucose tolerance;
5. Be careful when using the drug Regulon
Before using oral contraceptives such as Regulon, the user should conduct a general health examination and gynecological examination, including blood pressure measurement, blood test, breast examination and vaginal smear, then have may be repeated periodically during oral contraceptives.
During the period of taking Regulon, if the following symptoms appear, the drug must be stopped immediately, a non-hormonal method of contraception should be applied and a doctor should be consulted:
Blood clotting disorders, bleeding; History or symptoms of heart failure, kidney failure; Convulsions or a history of seizures; History or symptoms of migraine; History of gallstones; Having risk factors for estrogen-dependent tumors, estrogen-sensitive gynecological diseases such as fibroids and endometriosis; Diabetes mellitus; History or presentation of major depression; Sickle cell anemia; If the liver function test results are abnormal, the user needs to stop taking Regulon. When there are symptoms suggestive of thromboembolism, users should stop using Regulon immediately and consult a doctor for treatment:
Chest pain, spreading to the left arm; Respiratory failure, sudden shortness of breath; Unusually long-lasting headache, especially at first or worse than usual, or accompanied by symptoms such as sudden partial or complete loss of vision, double vision, aphasia, dizziness, lightheadedness severe dizziness, syncope with (or without) partial seizures, weakness with numbness affecting one side or the whole body, dyskinesia; The risk of blood clots increases when the user smokes, so do not smoke while using Regulon contraceptives, especially in people over 35 years of age. Regulon's contraceptive effectiveness may be reduced if, after several months of taking the pill, irregular, spotty, or extra-menstrual bleeding occurs. If a period is still absent by the end of the second cycle of Regulon or the menstrual disturbances have not resolved, the user should discontinue Regulon and rule out pregnancy before resuming oral contraceptives. .
Epidemiological studies show that the use of oral contraceptives (such as Regulon) in early pregnancy does not increase the risk of birth defects and is not teratogenic.
Regulon medicine can reduce lactation and change the composition of milk, in addition, Regulon also passes into breast milk, so it should not be used for this subject.
6. Regulon drug interactions
Some medications can interfere with the effectiveness of Regulon, including reducing the effectiveness of birth control or causing bleeding outside of the menstrual cycle. These drugs include:
Epilepsy drugs such as Primidon, Phenytoin, Barbiturates, Hydantoin, Carbamazepine, Topiramate...; TB medicines such as Rifampicin, Rifabutin, Isoniazid; Anti-inflammatory drugs such as Dexamethasone or Phenylbutazone; HIV medicines (including Ritonavir, Nelfinavir, Nevirapine, Efavirenz) or antibiotics (such as Ampicillin, Chloramphenicol, Neomycin, Nitrofurantoin, Penicillin V, Sulfonamide, Tetracycline); antifungal drugs such as Griseofulvin, Fluconazole, Itraconazole and Ketoconazole; Pulmonary hypertension medicine (Bosentan); Medicines for sleep disorders, anxiety, or migraines. Conversely, Regulon may affect the effect of other drugs, including:
Cyclosporin; Theophylline ; Metoprolol; Tricyclic antidepressants; Oral anticoagulants; Types of Vitamins; Glucocorticoids; Some benzodiazepine active ingredients such as Diazepam, Lorazepam, Alprazolam, Clorazepate, Flurazepam, Halazepam, Prazepam, Temazepam; Using Regulon with Troleandomycin (an antibiotic) may increase the risk of certain liver diseases.
Oral contraceptives such as Regulon may decrease glucose tolerance and increase the need for insulin or oral diabetes medications.
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