Pylokit is a gastrointestinal medication containing three main components: lansoprazole, tinidazole, and clarithromycin. It is indicated for the treatment of chronic gastritis with H. pylori infection and peptic ulcers. So, what are the uses of Pylokit?
1. What is Pylokit?
Pylokit is a gastrointestinal drug which is formulated in the form of tablets or capsules with the main ingredients including:
- Lansoprazole 30mg: A benzimidazole derivative with anti-secretory action in the stomach.
- Tinidazole 500mg: A 5-nitroimidazole compound with a longer duration of action than metronidazole, effective against protozoa and anaerobic bacteria. It is considered a highly effective drug against H. pylori due to its mechanism of action in destroying DNA chains or inhibiting DNA synthesis.
- Clarithromycin 250mg: Inhibits protein synthesis in susceptible bacteria by binding to the 50s ribosomal subunit. Clarithromycin is very effective against H. pylori, making it a rational choice in the treatment of H. pylori eradication.
2. Indications and contraindications of Pylokit
2.1 Indications of Pylokit
Indications of Pylokit include::
- Peptic ulcer
- Chronic gastritis
In addition to these uses, Pylokit may also be used to treat other medical conditions not listed above. Therefore, before dosing, please consult your doctor for advice to use the medication effectively.
2.2 Contraindications
Pylokit is contraindicated in patients who are hypersensitive to any component of the drug,
- Children
- Pregnant women
- Breastfeeding women
3. Instruction for use and dosage of Pylokit
3.1. Instruction for use
Pylokit is formulated in tablet form, so it is taken orally and 1 hour before meals or 2 hours after meals. You should take the medicine with a full glass of water to avoid irritating the stomach.
3.2. Dosage
The dosage of Pylokit will depend on the patient's condition and age. Patients should take 1 tablet of lansoprazole, 1 tablet of tinidazole, and 1 tablet of clarithromycin each time for 7 days, then maintain with lansoprazole 30mg/day for 3 weeks.
Please note that: The above dosage is for reference only. Patients should use
Pylokit regularly to get the most benefit from it. To use the drug safely, take Pylokit as instructed by your doctor, do not overdose, underdose, or use it for longer than prescribed. Absolutely do not abuse the drug for too long or increase the dosage of the drug without doctor’s advice.
4. Unwanted effects of Pylokit
Some possible unwanted effects of Pylokit include:
- Loss of appetite
- Nausea, vomiting
- Gastrointestinal discomfort
- Metallic taste and transient increase in liver enzymes
- Rash
- Itching
- Hives
Before prescribing, doctors always consider the benefits and effectiveness of Pylokit over the risk of side effects. However, some cases when using Pylokit may still experience adverse reactions. Therefore, when there are unusual signs after taking the drug, especially when there is a serious allergic reaction with accompanying signs such as difficulty in breathing, severe dizziness, swelling, rash or itching of the face, throat, tongue, ... In this case, patients need to notify the medical staff immediately for immediate intervention.
5. Some precautions of using Pylokit
Some precautions of using Pylokit include:
- Inform your doctor about any history of allergy to Pylokit or any other allergies. Pylokit may contain inactive ingredients of the drug and may cause allergic reactions or other serious problems.
- Report all medications you are using, including prescription, over-the-counter, herbal, and supplements, as well as foods, dyes, or preservatives.
- Use Pylokit with caution in patients with liver or kidney disease, exclude skin cancer, and avoid alcohol while taking the medication.
6. Management of missed dose and overdose of Pylokit
6.1. Missed dose
If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue taking the medication as scheduled. Do not double the dose.
6.2. Overdose
Overdosing on Pylokit can cause serious symptoms such as nausea, vomiting, abdominal pain, weakness, ... If you overdose, you should stop using the drug and go to a medical facility for examination and emergency treatment.
7. Drug interactions
Drug interactions can reduce the effectiveness of Pylokit or increase the effects of adverse reactions. Notify your doctor about all other medications you are taking, including vitamins, over-the-counter medications, prescription medications, and herbal products. Some drugs that may interact with Pylokit that patients need to pay attention to include:
- Theophylline
- Terfenadine
- Astemizole
- Itraconazole
- Cisapride
- Oral anticoagulants
- Iron
- Ampicillin
Store Pylokit at room temperature, away from light, and avoid damp places. Do not store Pylokit in damp places or in the freezer. Each type of drug has different storage methods, so please read the instructions for storing Pylokit on the packaging carefully, or ask your pharmacist. Keep Pylokit out of the reach of children and pets. When the drug is damaged and can no longer be used or has expired, dispose of the drug according to the correct procedure.
In summary, Pylokit is a gastrointestinal drug containing three main components: lansoprazole, tinidazole, and clarithromycin, indicated for the treatment of chronic gastritis with H. pylori infection and peptic ulcers. However, Pylokit can cause some side effects and drug interactions, so inform your doctor about all the medications you are using to reduce the risk of side effects and at the same time increase the effectiveness of the treatment.
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