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Pivalone 1% has the main ingredient containing tixocortol pivalate, which is prepared in the form of a nasal spray suspension, packaged in a box of 1 plastic bottle of 10ml. Complying with indications, the dose of Pivalone 1% will help patients improve treatment efficiency and avoid unwanted side effects.
1. What is Pivalone?
1.1 Pharmacodynamics of Pivalone 1% Tixocortol pivalate in Pivalone 1% is a corticosteroid that does not have any systemic effects other than the effect at the site of administration.
Pivalone 1% will be absorbed through the mucous-secreting epithelial cells in the nasal mucosa by peristalsis of the pili on the cell surface.
1.2 Pivalone 1% Pharmacokinetics Studies conducted in animals and humans show that the active ingredient tixocortol pivalate in Pivalone 1% is extremely rapidly metabolized, so it will not cause any systemic effects.
Active ingredient Tixocortol pivalate can be well absorbed orally. However, even when a large amount (2 g) is ingested by the patient, only inactive metabolites, but no glucocorticoid effects, are found in the systemic circulation. This is due to the very rapid breakdown of the active ingredient tixocortol pivalate, mainly in the liver.
2. Indications of Pivalone 1%
Pivalone 1% is indicated in the treatment of inflammatory and allergic diseases in the nasopharyngeal area such as:
Allergic rhinitis; Acute and chronic congestive rhinitis; Vasomotor rhinitis.
3. Contraindications of Pivalone 1%
Pivalone 1% is contraindicated for:
People who are sensitive to the ingredients in Pivalone 1%; People with nosebleeds. People with severe superinfection on the spot.
4. Dosage and how to use Pivalone 1%
How to use: Pivalone 1% is used by spraying into the nose. Patients should shake the bottle of Pivalone 1% vigorously before each use. Then open the protective cap of the bottle and test spray vertically into the nose, while pressing firmly on the valve. Remember to close the lid after using the medicine.
Dosage: The patient sprays 1-2 times into each nostril. Spray 2-4 times a day.
How to deal with missed dose or overdose of Pivalone 1%:
In case of missed dose of Pivalone 1%, it is advisable to supplement as soon as possible. However, if it is almost time for the next dose, skip the missed dose of Pivalone 1% and use a new dose. When using Pivalone 1% drug overdose, the patient should stop the drug immediately and go to the nearest medical facility for timely treatment.
5. Undesirable effects of Pivalone 1%
When using Pivalone 1%, patients may experience unwanted effects such as:
Allergies; Angioedema ; Dry nasal mucosa; Nasal pain; Face edema. Although these side effects will disappear when Pivalone 1% is stopped, if they are encountered, the patient should also inform the doctor or pharmacist for appropriate treatment.
6. Notes when using Pivalone 1%
Need to clean the nose thoroughly before using Pivalone 1%. If signs of systemic infection are present, treatment with a systemic antibiotic should be considered instead of Pivalone 1%. Care should be taken when using Pivalone 1% for people with severe liver and kidney failure. Breastfeeding women should consult their doctor before taking Pivalone 1%. Absolutely do not use when Pivalone 1% has signs of discoloration, mold, watery or expired. Above is all information about Pivalone 1% drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Pivalone 1% at home because it may encounter unwanted side effects.
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