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Phabacarb 25 belongs to the group of hemostatic drugs with the main ingredient carbazochrome, which is often used before surgical surgery and to treat capillary bleeding. So how does Phabacarb work?
1. Uses of Phabacarb 25
Phabacarb drug has the main ingredient containing carbazochrome sodium sulfonate which acts on the capillaries, inhibits the increase in capillary permeability and increases the strength of the vessel wall. This helps to somewhat shorten the bleeding time (hemostasis) without affecting the coagulation of the fibrinolytic system. In terms of pharmacokinetics, if 50 mg carbazochrome is given intravenously, the half-life of the plasma concentration is about 40 minutes, and when 150 mg of carbazochrome is given orally, the half-life is about 0.5-1. hours. The amount of carbazochrome sodium sulfonate excreted in the urine is consistent with plasma drug concentrations and peaks 0.5-1.5 hours after oral administration, and is excreted in the urine within 24 hours of oral administration.
Phabacarb is usually indicated in the following cases:
Hemostasis in preparation for surgery and treatment of capillary hemorrhage Patients with bleeding tendency due to decreased capillary resistance and increased capillary permeability Skin, mucosa and inner membrane bleeding, fundus hemorrhage, kidney failure and dysmenorrhea Abnormal bleeding during and after activity due to decreased capillary resistance Phabacarb is contraindicated in patients with a history of allergic reactions. reaction to carbazochrome sodium sulfonate or any of the ingredients in Phabacarb.
2. Dosage of Phabacarb
Phabacarb can be administered by injection or intravenous infusion. Depending on the subjects and treatment goals, the dosage of Phabacarb will be different, specifically as follows:
Adults: 25-100 mg/day, injection or infusion Oral: adults take 1-3 tablets /day, take 1 hour before meals and children from 30 months to 15 years old can take a dose of 1-2 tablets / day For the purpose of stopping bleeding before surgery, it can be used before and half an hour before surgery
3. Side effects of Phabacarb
In some patients when using Phabacarb, side effects may occur such as:
Hypersensitivity reactions: rash Anorexia, upset stomach,... When experiencing the above undesirable effects, it is necessary to Stop using the drug and notify your doctor immediately for treatment
4. Be careful when using Phabacarb
Some general notes when using Phabacarb drug include:
Caution when using Phabacarb drug for patients with a history of hypersensitivity to the drug Due to the elderly or having reduced physiological function, it should be cautious and reduced The dose of Phabacarb when used as well as close monitoring The urobilirubin test may become positive due to metabolites of carbazochrome sodium sulfonate. Phabacarb should only be used during pregnancy or lactation if clearly needed. Phabacarb 25 belongs to the group of hemostatic drugs, so before using it, patients should carefully read the instructions for use and consult a doctor and pharmacist. Using the right medicine for the right purpose will help the treatment process to be better.
